DR info

Clinical trials : 126 / Drugs : 135 - (DrugBank : 42) / Drug target genes : 46 - Drug target pathways : 162

Hypertrophic cardiomyopathy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
58	Hypertrophic cardiomyopathy	-
13	Multiple sclerosis/Neuromyelitis optica	22.617
46	Malignant rheumatoid arthritis	20.574
6	Parkinson disease	19.292
51	Scleroderma	16.825
86	Pulmonary arterial hypertension	16.016
96	Crohn disease	15.928
97	Ulcerative colitis	12.948
113	Muscular dystrophy	12.288
222	Primary nephrotic syndrome	12.158
2	Amyotrophic lateral sclerosis	10.630
226	Interstitial cystitis with Hunners ulcer	9.914
85	Idiopathic interstitial pneumonia	9.724
28	Systemic amyloidosis	8.849
38	Stevens-Johnson syndrome	8.739
107	Juvenile idiopathic arthritis	8.615
34	Neurofibromatosis	8.166
50	Dermatomyositis	7.910
164	Oculocutaneous albinism	7.145
70	Spinal stenosis	7.031
84	Sarcoidosis	6.574
65	Primary immunodeficiency	6.406
299	Cystic fibrosis	6.299
151	Rasmussen encephalitis	6.000
298	Hereditary pancreatitis	5.846
67	Polycystic kidney disease	5.842
127	Frontotemporal lobar degeneration	5.700
168	Ehlers-Danlos syndrome	5.671
228	Bronchiolitis obliterans	5.347
167	Marfan syndrome	5.206
90	Retinitis pigmentosa	5.204
302	Leber hereditary optic neuropathy	5.000
256	Muscle glycogenosis	4.637
11	Myasthenia gravis	4.594
36	Epidermolysis bullosa	4.424
57	Idiopathic dilated cardiomyopathy	4.250
53	Sjogren syndrome	4.217
269	Pyogenic arthritis	3.811
224	Purpura nephritis	3.811
227	Osler disease	3.652
193	Prader-Willi syndrome	3.636
39	Toxic epidermal necrolysis	3.614
66	IgA nephropathy	3.568
158	Tuberous sclerosis	3.568
26	HTLV-1-associated myelopathy	3.419
272	Fibrodysplasia ossificans progressiva	3.385
55	Relapsing polychondritis	3.375
160	Congenital ichthyosis	3.346
286	Hereditary sideroblastic anemia	3.320
5	Progressive supranuclear palsy	3.301
156	Rett syndrome	3.111
140	Dorabe syndrome	3.059
144	Lennox-Gastaut syndrome	3.031
210	Single Ventricle	3.000
41	Giant cell arteritis	2.949
56	Behcet disease	2.815
218	Alport syndrome	2.778
49	Systemic lupus erythematosus	2.778
1	Spinal and bulbar muscular atrophy	2.760
10	Charcot-Marie-Tooth disease	2.557
63	Idiopathic thrombocytopenic purpura	2.519
45	Eosinophilic granulomatosis with Polyangiitis	2.500
215	Tetralogy of Fallot	2.500
225	Congenital nephrogenic diabetes insipidus	2.416
95	Autoimmune hepatitis	2.408
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.387
81	Congenital adrenal hyperplasia	2.387
162	Pemphigoid	2.289
231	Alpha-1-antitrypsin deficiency	2.217
93	Primary biliary cholangitis	2.217
17	Multiple system atrophy	2.208
284	Diamond-Blackfan anemia	2.182
20	Adrenoleukodystrophy	2.182
274	Osteogenesis Imperfecta	2.121
280	Huge arteriovenous malformation with cervicofacial or limb lesion	2.121
19	Lysosomal storage disease	2.106
40	Takayasu arteritis	2.010
337	Homocystinuria	2.000
8	Huntington disease	1.968
169	Menkes disease	1.963
170	Occipital horn syndrome	1.963
42	Polyarteritis nodosa	1.962
64	Thrombotic thrombocytopenic purpura	1.921
326	Osteopetrosis	1.921
22	Moyamoya disease	1.875
149	Hemiconvulsion hemiplegia epilepsy syndrome	1.838
285	Fanconi anemia	1.800
114	Non-dystrophic myotonia syndrome	1.765
283	Acquired pure red cell aplasia	1.765
62	Paroxysmal nocturnal hemoglobinuria	1.587
60	Aplastic anemia	1.500
88	Chronic thromboembolic pulmonary hypertension	1.462
61	Autoimmune hemolytic anemia	1.417
102	Rubinstein-Taybi syndrome	1.393
89	Lymphangioleiomyomatosis	1.350
206	Fragile X syndrome	1.333
331	Idiopathic multicentric castleman disease	1.243
118	Myelomeningocele	1.242
288	Autoimmune acquired coagulation factor deficiency	1.148
271	Ankylosing spondylitis	1.067
106	Cryopyrin-associated periodic syndrome	1.042
251	Urea cycle disorder	1.042
108	TNF receptor-associated periodic syndrome	1.000
267	Hyper-IgD syndrome	1.000