DR info

Clinical trials : 245 / Drugs : 318 - (DrugBank : 86) / Drug target genes : 44 - Drug target pathways : 166

Aplastic anemia and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
60	Aplastic anemia	-
46	Malignant rheumatoid arthritis	27.190
285	Fanconi anemia	24.679
65	Primary immunodeficiency	24.286
13	Multiple sclerosis/Neuromyelitis optica	23.827
49	Systemic lupus erythematosus	22.307
96	Crohn disease	20.222
284	Diamond-Blackfan anemia	17.581
19	Lysosomal storage disease	13.696
283	Acquired pure red cell aplasia	13.393
53	Sjogren syndrome	13.333
164	Oculocutaneous albinism	13.160
97	Ulcerative colitis	13.136
51	Scleroderma	12.451
11	Myasthenia gravis	11.829
41	Giant cell arteritis	10.898
62	Paroxysmal nocturnal hemoglobinuria	10.889
45	Eosinophilic granulomatosis with Polyangiitis	10.507
55	Relapsing polychondritis	10.323
40	Takayasu arteritis	9.893
326	Osteopetrosis	9.857
63	Idiopathic thrombocytopenic purpura	9.617
85	Idiopathic interstitial pneumonia	9.584
28	Systemic amyloidosis	9.487
50	Dermatomyositis	9.397
107	Juvenile idiopathic arthritis	9.143
234	Peroxisomal disease (except Adrenoleukodystrophy)	8.730
162	Pemphigoid	8.626
228	Bronchiolitis obliterans	8.626
42	Polyarteritis nodosa	8.512
64	Thrombotic thrombocytopenic purpura	8.463
93	Primary biliary cholangitis	8.400
20	Adrenoleukodystrophy	8.104
35	Pemphigus	8.104
286	Hereditary sideroblastic anemia	8.000
222	Primary nephrotic syndrome	7.728
95	Autoimmune hepatitis	7.581
61	Autoimmune hemolytic anemia	7.543
56	Behcet disease	7.265
2	Amyotrophic lateral sclerosis	7.017
66	IgA nephropathy	6.367
39	Toxic epidermal necrolysis	6.234
38	Stevens-Johnson syndrome	6.171
224	Purpura nephritis	6.171
151	Rasmussen encephalitis	6.000
36	Epidermolysis bullosa	5.528
84	Sarcoidosis	5.447
299	Cystic fibrosis	5.239
113	Muscular dystrophy	5.172
271	Ankylosing spondylitis	5.059
302	Leber hereditary optic neuropathy	5.000
300	IgG4-related disease	4.978
269	Pyogenic arthritis	4.978
44	Wegener granulomatosis	4.959
331	Idiopathic multicentric castleman disease	4.839
6	Parkinson disease	4.645
160	Congenital ichthyosis	4.402
26	HTLV-1-associated myelopathy	4.386
226	Interstitial cystitis with Hunners ulcer	4.276
43	Microscopic polyangiitis	4.083
158	Tuberous sclerosis	3.747
274	Osteogenesis Imperfecta	3.061
227	Osler disease	2.942
270	Chronic recurrent multifocal osteomyelitis	2.794
83	Addison disease	2.794
94	Primary sclerosing cholangitis	2.481
34	Neurofibromatosis	2.119
77	Growth hormone secreting pituitary adenoma	2.000
16	Crow-Fukase syndrome	1.886
256	Muscle glycogenosis	1.853
76	Pituitary gonadotropin secretion hyperthyroidism	1.607
81	Congenital adrenal hyperplasia	1.587
14	Chronic inflammatory demyelinating polyneuropathy	1.587
86	Pulmonary arterial hypertension	1.575
58	Hypertrophic cardiomyopathy	1.500
90	Retinitis pigmentosa	1.487
229	Autoimmune pulmonary alveolar proteinosis	1.365
172	Hypophosphatasia	1.365
127	Frontotemporal lobar degeneration	1.146
235	Hypoparathyroidism	1.048
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
317	Trifunctional protein deficiency	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000