DR info

Clinical trials : 275 / Drugs : 258 - (DrugBank : 82) / Drug target genes : 36 - Drug target pathways : 140

IgA nephropathy and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
66	IgA nephropathy	-
46	Malignant rheumatoid arthritis	21.729
13	Multiple sclerosis/Neuromyelitis optica	21.455
49	Systemic lupus erythematosus	20.839
222	Primary nephrotic syndrome	18.088
96	Crohn disease	13.650
224	Purpura nephritis	13.440
61	Autoimmune hemolytic anemia	11.571
19	Lysosomal storage disease	10.411
97	Ulcerative colitis	10.358
6	Parkinson disease	10.094
51	Scleroderma	9.572
283	Acquired pure red cell aplasia	9.371
162	Pemphigoid	9.164
85	Idiopathic interstitial pneumonia	8.718
2	Amyotrophic lateral sclerosis	8.122
50	Dermatomyositis	8.050
62	Paroxysmal nocturnal hemoglobinuria	7.408
11	Myasthenia gravis	7.189
228	Bronchiolitis obliterans	6.982
65	Primary immunodeficiency	6.907
93	Primary biliary cholangitis	6.818
60	Aplastic anemia	6.367
63	Idiopathic thrombocytopenic purpura	6.217
284	Diamond-Blackfan anemia	6.104
64	Thrombotic thrombocytopenic purpura	6.075
107	Juvenile idiopathic arthritis	5.934
53	Sjogren syndrome	5.835
56	Behcet disease	5.762
113	Muscular dystrophy	5.718
45	Eosinophilic granulomatosis with Polyangiitis	5.657
95	Autoimmune hepatitis	5.481
285	Fanconi anemia	5.238
36	Epidermolysis bullosa	5.150
299	Cystic fibrosis	5.100
41	Giant cell arteritis	5.022
302	Leber hereditary optic neuropathy	5.000
164	Oculocutaneous albinism	4.958
28	Systemic amyloidosis	4.714
234	Peroxisomal disease (except Adrenoleukodystrophy)	4.667
42	Polyarteritis nodosa	4.629
84	Sarcoidosis	4.469
86	Pulmonary arterial hypertension	4.287
151	Rasmussen encephalitis	4.286
218	Alport syndrome	4.286
274	Osteogenesis Imperfecta	4.200
20	Adrenoleukodystrophy	4.073
269	Pyogenic arthritis	4.013
226	Interstitial cystitis with Hunners ulcer	3.973
39	Toxic epidermal necrolysis	3.740
58	Hypertrophic cardiomyopathy	3.568
55	Relapsing polychondritis	3.514
286	Hereditary sideroblastic anemia	3.393
158	Tuberous sclerosis	3.239
43	Microscopic polyangiitis	3.159
26	HTLV-1-associated myelopathy	3.128
271	Ankylosing spondylitis	3.033
38	Stevens-Johnson syndrome	3.017
300	IgG4-related disease	3.017
109	Atypical hemolytic uremic syndrome	3.000
40	Takayasu arteritis	2.968
326	Osteopetrosis	2.893
160	Congenital ichthyosis	2.686
44	Wegener granulomatosis	2.449
35	Pemphigus	2.384
90	Retinitis pigmentosa	2.200
17	Multiple system atrophy	2.043
257	Hepatic glycogenosis	2.000
16	Crow-Fukase syndrome	1.903
211	Hypoplastic left heart syndrome	1.903
94	Primary sclerosing cholangitis	1.842
227	Osler disease	1.646
14	Chronic inflammatory demyelinating polyneuropathy	1.638
83	Addison disease	1.629
88	Chronic thromboembolic pulmonary hypertension	1.547
288	Autoimmune acquired coagulation factor deficiency	1.244
57	Idiopathic dilated cardiomyopathy	1.171
167	Marfan syndrome	1.080
75	Cushing disease	1.060
333	Hutchinson-Gilford syndrome	1.057
91	Budd-Chiari syndrome	1.057
235	Hypoparathyroidism	1.057
137	Focal cortical dysplasia	1.000
192	Cockayne syndrome	1.000
277	Lymphangiomatosis	1.000
281	Klippel-Trenaunay-Weber syndrome	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000