DR info

Clinical trials : 95 / Drugs : 169 - (DrugBank : 61) / Drug target genes : 68 - Drug target pathways : 90

Spinal stenosis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
70	Spinal stenosis	-
46	Malignant rheumatoid arthritis	50.084
6	Parkinson disease	50.043
13	Multiple sclerosis/Neuromyelitis optica	49.301
96	Crohn disease	40.060
298	Hereditary pancreatitis	30.751
2	Amyotrophic lateral sclerosis	30.457
97	Ulcerative colitis	28.650
22	Moyamoya disease	28.000
5	Progressive supranuclear palsy	26.138
8	Huntington disease	24.188
17	Multiple system atrophy	24.163
231	Alpha-1-antitrypsin deficiency	23.353
21	Mitochondrial disease	22.774
206	Fragile X syndrome	22.727
156	Rett syndrome	21.179
205	Fragile X syndrome related disease	20.240
36	Epidermolysis bullosa	19.837
193	Prader-Willi syndrome	19.492
140	Dorabe syndrome	18.778
144	Lennox-Gastaut syndrome	17.393
3	Spinal muscular atrophy	16.795
272	Fibrodysplasia ossificans progressiva	16.783
152	PCDH19 related syndrome	16.000
18	Spinocerebellar degeneration	15.674
158	Tuberous sclerosis	15.273
34	Neurofibromatosis	14.952
226	Interstitial cystitis with Hunners ulcer	14.455
201	Angelman syndrome	14.132
113	Muscular dystrophy	13.857
296	Biliary atresia	13.364
84	Sarcoidosis	13.197
145	West syndrome	12.325
51	Scleroderma	11.065
98	Eosinophilic gastrointestinal disease	10.656
155	Acquired aphasia with convulsive disorder	10.566
86	Pulmonary arterial hypertension	10.560
215	Tetralogy of Fallot	10.100
169	Menkes disease	9.000
170	Occipital horn syndrome	9.000
127	Frontotemporal lobar degeneration	8.727
75	Cushing disease	8.710
58	Hypertrophic cardiomyopathy	7.031
78	Hypopituitarism	6.479
118	Myelomeningocele	6.218
10	Charcot-Marie-Tooth disease	6.083
11	Myasthenia gravis	5.576
85	Idiopathic interstitial pneumonia	5.165
167	Marfan syndrome	5.123
288	Autoimmune acquired coagulation factor deficiency	5.114
280	Huge arteriovenous malformation with cervicofacial or limb lesion	4.987
4	Primary lateral sclerosis	4.909
107	Juvenile idiopathic arthritis	4.448
168	Ehlers-Danlos syndrome	4.182
28	Systemic amyloidosis	3.967
1	Spinal and bulbar muscular atrophy	3.818
256	Muscle glycogenosis	3.484
323	Aromatic L-amino acid decarboxylase deficiency	3.000
57	Idiopathic dilated cardiomyopathy	2.946
210	Single Ventricle	2.727
38	Stevens-Johnson syndrome	2.727
90	Retinitis pigmentosa	2.655
67	Polycystic kidney disease	2.450
271	Ankylosing spondylitis	2.341
81	Congenital adrenal hyperplasia	2.304
251	Urea cycle disorder	2.284
235	Hypoparathyroidism	2.284
49	Systemic lupus erythematosus	2.259
203	22q11.2 deletion syndrome	2.029
337	Homocystinuria	2.000
299	Cystic fibrosis	1.956
278	Huge lymphatic malformation with cervicofacial lesion	1.855
114	Non-dystrophic myotonia syndrome	1.662
254	Porphyria	1.595
65	Primary immunodeficiency	1.595
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy	1.568
47	Buerger disease	1.568
53	Sjogren syndrome	1.539
43	Microscopic polyangiitis	1.316
300	IgG4-related disease	1.244
212	Tricuspid atresia	1.210
45	Eosinophilic granulomatosis with Polyangiitis	1.077
19	Lysosomal storage disease	1.020
111	Congenital myopathy	1.000
317	Trifunctional protein deficiency	1.000
68	Ossification of the ligamentum flavum	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000