DR info

Clinical trials : 492 / Drugs : 341 - (DrugBank : 47) / Drug target genes : 45 - Drug target pathways : 100

Hypopituitarism and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
78	Hypopituitarism	-
13	Multiple sclerosis/Neuromyelitis optica	28.783
46	Malignant rheumatoid arthritis	23.376
96	Crohn disease	20.820
6	Parkinson disease	20.639
2	Amyotrophic lateral sclerosis	18.206
21	Mitochondrial disease	17.395
97	Ulcerative colitis	14.922
299	Cystic fibrosis	12.424
265	Lipodystrophy	12.084
226	Interstitial cystitis with Hunners ulcer	10.355
113	Muscular dystrophy	8.579
49	Systemic lupus erythematosus	8.124
8	Huntington disease	7.758
236	Pseudohypoparathyroidism	7.287
70	Spinal stenosis	6.479
206	Fragile X syndrome	6.046
215	Tetralogy of Fallot	5.420
63	Idiopathic thrombocytopenic purpura	4.767
212	Tricuspid atresia	4.705
246	Methylmalonic acidemia	4.535
107	Juvenile idiopathic arthritis	4.495
3	Spinal muscular atrophy	4.462
65	Primary immunodeficiency	4.436
85	Idiopathic interstitial pneumonia	4.331
17	Multiple system atrophy	4.238
4	Primary lateral sclerosis	4.211
5	Progressive supranuclear palsy	4.146
75	Cushing disease	3.519
271	Ankylosing spondylitis	3.412
323	Aromatic L-amino acid decarboxylase deficiency	3.000
127	Frontotemporal lobar degeneration	2.764
205	Fragile X syndrome related disease	2.762
74	Prolactin secreting pituitary adenoma	2.761
156	Rett syndrome	2.678
84	Sarcoidosis	2.627
18	Spinocerebellar degeneration	2.618
86	Pulmonary arterial hypertension	2.485
81	Congenital adrenal hyperplasia	2.415
51	Scleroderma	2.411
251	Urea cycle disorder	2.301
203	22q11.2 deletion syndrome	2.151
11	Myasthenia gravis	2.029
337	Homocystinuria	2.000
139	Congenital cerebral hypomyelination	2.000
120	Hereditary dystonia	2.000
50	Dermatomyositis	1.972
294	Congenital diaphragmatic hernia	1.882
211	Hypoplastic left heart syndrome	1.882
222	Primary nephrotic syndrome	1.789
67	Polycystic kidney disease	1.636
83	Addison disease	1.602
124	Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy	1.602
193	Prader-Willi syndrome	1.428
280	Huge arteriovenous malformation with cervicofacial or limb lesion	1.403
171	Wilson disease	1.364
80	Resistance to thyroid hormone	1.364
22	Moyamoya disease	1.360
210	Single Ventricle	1.261
118	Myelomeningocele	1.253
162	Pemphigoid	1.240
56	Behcet disease	1.184
34	Neurofibromatosis	1.176
288	Autoimmune acquired coagulation factor deficiency	1.172
169	Menkes disease	1.136
170	Occipital horn syndrome	1.136
90	Retinitis pigmentosa	1.020
232	Carney complex	1.000
191	Werner syndrome	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000