DR info

Clinical trials : 147 / Drugs : 176 - (DrugBank : 43) / Drug target genes : 49 - Drug target pathways : 110

Retinitis pigmentosa and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
90	Retinitis pigmentosa	-
13	Multiple sclerosis/Neuromyelitis optica	35.338
6	Parkinson disease	21.490
86	Pulmonary arterial hypertension	16.969
2	Amyotrophic lateral sclerosis	14.535
115	Hereditary periodic paralysis	13.000
154	Epilepsy with continuous spikes and waves during slow sleep	13.000
230	Alveolar hypoventilation syndrome	11.778
114	Non-dystrophic myotonia syndrome	10.347
225	Congenital nephrogenic diabetes insipidus	8.667
155	Acquired aphasia with convulsive disorder	7.730
26	HTLV-1-associated myelopathy	7.684
97	Ulcerative colitis	7.218
65	Primary immunodeficiency	7.140
102	Rubinstein-Taybi syndrome	7.000
299	Cystic fibrosis	6.218
226	Interstitial cystitis with Hunners ulcer	6.188
39	Toxic epidermal necrolysis	6.174
85	Idiopathic interstitial pneumonia	6.169
164	Oculocutaneous albinism	6.137
96	Crohn disease	5.521
222	Primary nephrotic syndrome	5.484
58	Hypertrophic cardiomyopathy	5.204
140	Dorabe syndrome	5.204
4	Primary lateral sclerosis	5.133
302	Leber hereditary optic neuropathy	5.000
233	Wolfram syndrome	4.818
5	Progressive supranuclear palsy	4.612
50	Dermatomyositis	4.424
151	Rasmussen encephalitis	4.252
46	Malignant rheumatoid arthritis	4.120
51	Scleroderma	3.901
62	Paroxysmal nocturnal hemoglobinuria	3.856
224	Purpura nephritis	3.800
331	Idiopathic multicentric castleman disease	3.786
20	Adrenoleukodystrophy	3.740
34	Neurofibromatosis	3.548
113	Muscular dystrophy	3.390
160	Congenital ichthyosis	3.333
283	Acquired pure red cell aplasia	3.333
286	Hereditary sideroblastic anemia	3.316
127	Frontotemporal lobar degeneration	3.306
49	Systemic lupus erythematosus	3.293
89	Lymphangioleiomyomatosis	3.289
11	Myasthenia gravis	3.122
7	Corticobasal degeneration	3.005
323	Aromatic L-amino acid decarboxylase deficiency	3.000
107	Juvenile idiopathic arthritis	2.925
284	Diamond-Blackfan anemia	2.909
53	Sjogren syndrome	2.855
38	Stevens-Johnson syndrome	2.841
269	Pyogenic arthritis	2.841
17	Multiple system atrophy	2.737
74	Prolactin secreting pituitary adenoma	2.709
64	Thrombotic thrombocytopenic purpura	2.709
70	Spinal stenosis	2.655
63	Idiopathic thrombocytopenic purpura	2.496
45	Eosinophilic granulomatosis with Polyangiitis	2.490
215	Tetralogy of Fallot	2.490
144	Lennox-Gastaut syndrome	2.399
95	Autoimmune hepatitis	2.397
81	Congenital adrenal hyperplasia	2.381
55	Relapsing polychondritis	2.381
234	Peroxisomal disease (except Adrenoleukodystrophy)	2.381
256	Muscle glycogenosis	2.355
3	Spinal muscular atrophy	2.317
309	Progressive myoclonus epilepsy	2.296
66	IgA nephropathy	2.200
201	Angelman syndrome	2.171
212	Tricuspid atresia	2.163
274	Osteogenesis Imperfecta	2.114
227	Osler disease	2.108
40	Takayasu arteritis	1.998
61	Autoimmune hemolytic anemia	1.998
42	Polyarteritis nodosa	1.950
8	Huntington disease	1.944
326	Osteopetrosis	1.913
166	Pseudoxanthoma elasticum	1.873
36	Epidermolysis bullosa	1.857
149	Hemiconvulsion hemiplegia epilepsy syndrome	1.831
193	Prader-Willi syndrome	1.824
167	Marfan syndrome	1.796
285	Fanconi anemia	1.788
41	Giant cell arteritis	1.692
162	Pemphigoid	1.692
228	Bronchiolitis obliterans	1.692
93	Primary biliary cholangitis	1.637
158	Tuberous sclerosis	1.637
56	Behcet disease	1.612
156	Rett syndrome	1.545
60	Aplastic anemia	1.487
280	Huge arteriovenous malformation with cervicofacial or limb lesion	1.376
118	Myelomeningocele	1.240
28	Systemic amyloidosis	1.213
19	Lysosomal storage disease	1.193
288	Autoimmune acquired coagulation factor deficiency	1.143
169	Menkes disease	1.122
170	Occipital horn syndrome	1.122
254	Porphyria	1.100
37	Generalised pustular psoriasis	1.061
202	Smith-Magenis syndrome	1.041
78	Hypopituitarism	1.020
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000