DR info

Clinical trials : 298 / Drugs : 252 - (DrugBank : 59) / Drug target genes : 35 - Drug target pathways : 115

Primary biliary cholangitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
93	Primary biliary cholangitis	-
46	Malignant rheumatoid arthritis	31.451
49	Systemic lupus erythematosus	30.027
65	Primary immunodeficiency	25.630
51	Scleroderma	20.853
56	Behcet disease	18.822
42	Polyarteritis nodosa	18.022
96	Crohn disease	17.535
41	Giant cell arteritis	12.761
162	Pemphigoid	12.761
97	Ulcerative colitis	12.627
50	Dermatomyositis	12.536
53	Sjogren syndrome	12.118
85	Idiopathic interstitial pneumonia	10.847
28	Systemic amyloidosis	10.509
95	Autoimmune hepatitis	10.420
2	Amyotrophic lateral sclerosis	10.172
26	HTLV-1-associated myelopathy	9.812
284	Diamond-Blackfan anemia	9.657
160	Congenital ichthyosis	9.371
11	Myasthenia gravis	9.286
40	Takayasu arteritis	9.078
269	Pyogenic arthritis	8.989
55	Relapsing polychondritis	8.810
222	Primary nephrotic syndrome	8.536
271	Ankylosing spondylitis	8.468
60	Aplastic anemia	8.400
285	Fanconi anemia	8.370
19	Lysosomal storage disease	8.292
331	Idiopathic multicentric castleman disease	8.255
45	Eosinophilic granulomatosis with Polyangiitis	8.067
283	Acquired pure red cell aplasia	8.067
84	Sarcoidosis	7.997
164	Oculocutaneous albinism	7.953
107	Juvenile idiopathic arthritis	7.862
13	Multiple sclerosis/Neuromyelitis optica	7.837
66	IgA nephropathy	6.818
266	Familial mediterranean fever	6.612
224	Purpura nephritis	6.326
286	Hereditary sideroblastic anemia	6.300
44	Wegener granulomatosis	6.259
62	Paroxysmal nocturnal hemoglobinuria	6.259
20	Adrenoleukodystrophy	6.104
234	Peroxisomal disease (except Adrenoleukodystrophy)	5.943
274	Osteogenesis Imperfecta	5.355
34	Neurofibromatosis	5.202
210	Single Ventricle	5.089
228	Bronchiolitis obliterans	5.022
302	Leber hereditary optic neuropathy	5.000
61	Autoimmune hemolytic anemia	4.721
6	Parkinson disease	4.618
94	Primary sclerosing cholangitis	4.427
299	Cystic fibrosis	4.321
151	Rasmussen encephalitis	4.286
64	Thrombotic thrombocytopenic purpura	3.850
326	Osteopetrosis	3.850
39	Toxic epidermal necrolysis	3.740
43	Microscopic polyangiitis	3.159
38	Stevens-Johnson syndrome	3.017
300	IgG4-related disease	3.017
63	Idiopathic thrombocytopenic purpura	2.926
36	Epidermolysis bullosa	2.836
113	Muscular dystrophy	2.665
226	Interstitial cystitis with Hunners ulcer	2.600
35	Pemphigus	2.384
58	Hypertrophic cardiomyopathy	2.217
265	Lipodystrophy	2.176
79	Homozygous familial hypercholesterolemia	2.032
268	Nakajo-Nishimura syndrome	2.000
325	Hereditary autoinflammatory syndrome	2.000
263	Cerebrotendinous xanthomatosis	2.000
257	Hepatic glycogenosis	2.000
158	Tuberous sclerosis	1.881
227	Osler disease	1.646
90	Retinitis pigmentosa	1.637
270	Chronic recurrent multifocal osteomyelitis	1.629
256	Muscle glycogenosis	1.406
310	Congenital anomalies syndrome	1.371
229	Autoimmune pulmonary alveolar proteinosis	1.371
172	Hypophosphatasia	1.371
333	Hutchinson-Gilford syndrome	1.057
324	Methylglutaconic aciduria	1.000
260	Sitosterolemia	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000