DR info

Clinical trials : 2,630 / Drugs : 1,459 - (DrugBank : 265) / Drug target genes : 144 - Drug target pathways : 202

Ulcerative colitis and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)

ID	Diseases (Sorted by score)	Score
97	Ulcerative colitis	-
96	Crohn disease	91.853
13	Multiple sclerosis/Neuromyelitis optica	89.503
46	Malignant rheumatoid arthritis	82.158
6	Parkinson disease	79.226
2	Amyotrophic lateral sclerosis	51.216
8	Huntington disease	43.315
156	Rett syndrome	37.287
140	Dorabe syndrome	36.735
144	Lennox-Gastaut syndrome	36.225
21	Mitochondrial disease	35.709
84	Sarcoidosis	34.778
49	Systemic lupus erythematosus	34.003
206	Fragile X syndrome	33.960
107	Juvenile idiopathic arthritis	33.351
298	Hereditary pancreatitis	31.508
193	Prader-Willi syndrome	30.888
18	Spinocerebellar degeneration	30.613
50	Dermatomyositis	29.266
70	Spinal stenosis	28.650
231	Alpha-1-antitrypsin deficiency	28.225
17	Multiple system atrophy	27.480
271	Ankylosing spondylitis	25.078
158	Tuberous sclerosis	25.037
36	Epidermolysis bullosa	24.711
3	Spinal muscular atrophy	23.421
51	Scleroderma	23.361
226	Interstitial cystitis with Hunners ulcer	23.022
5	Progressive supranuclear palsy	22.800
41	Giant cell arteritis	21.488
98	Eosinophilic gastrointestinal disease	20.860
299	Cystic fibrosis	20.144
65	Primary immunodeficiency	19.838
205	Fragile X syndrome related disease	19.766
145	West syndrome	18.553
53	Sjogren syndrome	18.071
56	Behcet disease	17.343
34	Neurofibromatosis	16.297
113	Muscular dystrophy	16.169
272	Fibrodysplasia ossificans progressiva	16.030
152	PCDH19 related syndrome	16.000
162	Pemphigoid	15.795
201	Angelman syndrome	15.139
40	Takayasu arteritis	15.046
78	Hypopituitarism	14.922
86	Pulmonary arterial hypertension	14.247
203	22q11.2 deletion syndrome	14.000
265	Lipodystrophy	13.159
60	Aplastic anemia	13.136
58	Hypertrophic cardiomyopathy	12.948
75	Cushing disease	12.689
93	Primary biliary cholangitis	12.627
22	Moyamoya disease	12.381
155	Acquired aphasia with convulsive disorder	12.032
269	Pyogenic arthritis	11.424
85	Idiopathic interstitial pneumonia	11.071
296	Biliary atresia	10.443
63	Idiopathic thrombocytopenic purpura	10.443
66	IgA nephropathy	10.358
55	Relapsing polychondritis	10.154
222	Primary nephrotic syndrome	10.098
38	Stevens-Johnson syndrome	9.801
45	Eosinophilic granulomatosis with Polyangiitis	9.717
160	Congenital ichthyosis	9.717
284	Diamond-Blackfan anemia	9.408
285	Fanconi anemia	9.369
44	Wegener granulomatosis	8.498
164	Oculocutaneous albinism	8.477
224	Purpura nephritis	8.292
95	Autoimmune hepatitis	7.950
11	Myasthenia gravis	7.680
37	Generalised pustular psoriasis	7.603
127	Frontotemporal lobar degeneration	7.474
28	Systemic amyloidosis	7.267
90	Retinitis pigmentosa	7.218
42	Polyarteritis nodosa	7.091
256	Muscle glycogenosis	7.074
19	Lysosomal storage disease	7.061
283	Acquired pure red cell aplasia	7.051
286	Hereditary sideroblastic anemia	6.168
151	Rasmussen encephalitis	6.000
10	Charcot-Marie-Tooth disease	5.940
81	Congenital adrenal hyperplasia	5.483
236	Pseudohypoparathyroidism	5.350
302	Leber hereditary optic neuropathy	5.000
294	Congenital diaphragmatic hernia	5.000
20	Adrenoleukodystrophy	4.927
35	Pemphigus	4.927
43	Microscopic polyangiitis	4.763
39	Toxic epidermal necrolysis	4.579
228	Bronchiolitis obliterans	4.231
326	Osteopetrosis	4.224
62	Paroxysmal nocturnal hemoglobinuria	4.181
168	Ehlers-Danlos syndrome	4.084
246	Methylmalonic acidemia	4.002
225	Congenital nephrogenic diabetes insipidus	3.800
67	Polycystic kidney disease	3.785
167	Marfan syndrome	3.701
94	Primary sclerosing cholangitis	3.628
25	Progressive multifocal leukoencephalopathy	3.621
300	IgG4-related disease	3.449
15	Inclusion body myositis	3.387
64	Thrombotic thrombocytopenic purpura	3.255
26	HTLV-1-associated myelopathy	3.147
234	Peroxisomal disease (except Adrenoleukodystrophy)	3.126
171	Wilson disease	3.000
310	Congenital anomalies syndrome	3.000
229	Autoimmune pulmonary alveolar proteinosis	3.000
114	Non-dystrophic myotonia syndrome	2.932
215	Tetralogy of Fallot	2.932
179	Williams syndrome	2.855
4	Primary lateral sclerosis	2.795
274	Osteogenesis Imperfecta	2.715
218	Alport syndrome	2.704
1	Spinal and bulbar muscular atrophy	2.587
251	Urea cycle disorder	2.266
91	Budd-Chiari syndrome	2.266
202	Smith-Magenis syndrome	2.266
61	Autoimmune hemolytic anemia	2.207
77	Growth hormone secreting pituitary adenoma	2.000
268	Nakajo-Nishimura syndrome	2.000
325	Hereditary autoinflammatory syndrome	2.000
337	Homocystinuria	2.000
263	Cerebrotendinous xanthomatosis	2.000
257	Hepatic glycogenosis	2.000
282	Congenital dyserythropoietic anemia	2.000
120	Hereditary dystonia	2.000
227	Osler disease	1.751
149	Hemiconvulsion hemiplegia epilepsy syndrome	1.594
270	Chronic recurrent multifocal osteomyelitis	1.531
288	Autoimmune acquired coagulation factor deficiency	1.515
172	Hypophosphatasia	1.343
88	Chronic thromboembolic pulmonary hypertension	1.308
280	Huge arteriovenous malformation with cervicofacial or limb lesion	1.223
301	Macular dystrophy	1.042
57	Idiopathic dilated cardiomyopathy	1.042
79	Homozygous familial hypercholesterolemia	1.042
106	Cryopyrin-associated periodic syndrome	1.014
235	Hypoparathyroidism	1.014
71	Idiopathic osteonecrosis of the femoral head	1.014
317	Trifunctional protein deficiency	1.000
52	Mixed connective tissue disease	1.000
220	Rapidly progressive glomerulonephritis	1.000
30	Distal myopathy	1.000