98. Eosinophilic gastrointestinal disease Disease details / Clinical trials / Drug dev / DR info
Clinical trials : 172 / Drugs : 149 - (DrugBank : 39) / Drug target genes : 38 - Drug target pathways : 135
Eosinophilic gastrointestinal disease and other diseases between which drug repositioning (DR) might occur (Sakate and Kimura 2021) . Circle size: Number of drugs, Line breadth: Score (Drug repositionability)
| ID | Diseases (Sorted by score) | Score |
|---|---|---|
| 98 | Eosinophilic gastrointestinal disease | - |
| 13 | Multiple sclerosis/Neuromyelitis optica | 32.204 |
| 2 | Amyotrophic lateral sclerosis | 23.355 |
| 6 | Parkinson disease | 23.236 |
| 96 | Crohn disease | 21.977 |
| 97 | Ulcerative colitis | 20.860 |
| 46 | Malignant rheumatoid arthritis | 20.466 |
| 296 | Biliary atresia | 16.789 |
| 152 | PCDH19 related syndrome | 16.000 |
| 156 | Rett syndrome | 15.919 |
| 298 | Hereditary pancreatitis | 14.815 |
| 145 | West syndrome | 14.634 |
| 5 | Progressive supranuclear palsy | 14.066 |
| 205 | Fragile X syndrome related disease | 13.816 |
| 201 | Angelman syndrome | 13.339 |
| 17 | Multiple system atrophy | 13.115 |
| 18 | Spinocerebellar degeneration | 13.109 |
| 158 | Tuberous sclerosis | 13.095 |
| 36 | Epidermolysis bullosa | 12.758 |
| 84 | Sarcoidosis | 12.255 |
| 272 | Fibrodysplasia ossificans progressiva | 12.248 |
| 8 | Huntington disease | 12.195 |
| 75 | Cushing disease | 11.929 |
| 22 | Moyamoya disease | 11.819 |
| 21 | Mitochondrial disease | 11.770 |
| 155 | Acquired aphasia with convulsive disorder | 11.627 |
| 34 | Neurofibromatosis | 11.031 |
| 231 | Alpha-1-antitrypsin deficiency | 10.704 |
| 70 | Spinal stenosis | 10.656 |
| 140 | Dorabe syndrome | 10.573 |
| 144 | Lennox-Gastaut syndrome | 10.501 |
| 193 | Prader-Willi syndrome | 10.366 |
| 3 | Spinal muscular atrophy | 10.241 |
| 206 | Fragile X syndrome | 10.182 |
| 299 | Cystic fibrosis | 5.324 |
| 86 | Pulmonary arterial hypertension | 5.276 |
| 19 | Lysosomal storage disease | 3.535 |
| 254 | Porphyria | 3.334 |
| 53 | Sjogren syndrome | 3.125 |
| 226 | Interstitial cystitis with Hunners ulcer | 2.963 |
| 85 | Idiopathic interstitial pneumonia | 2.614 |
| 162 | Pemphigoid | 2.426 |
| 26 | HTLV-1-associated myelopathy | 2.264 |
| 65 | Primary immunodeficiency | 2.133 |
| 51 | Scleroderma | 2.017 |
| 282 | Congenital dyserythropoietic anemia | 2.000 |
| 222 | Primary nephrotic syndrome | 1.861 |
| 49 | Systemic lupus erythematosus | 1.552 |
| 61 | Autoimmune hemolytic anemia | 1.488 |
| 107 | Juvenile idiopathic arthritis | 1.469 |
| 300 | IgG4-related disease | 1.353 |
| 228 | Bronchiolitis obliterans | 1.275 |
| 45 | Eosinophilic granulomatosis with Polyangiitis | 1.192 |
| 271 | Ankylosing spondylitis | 1.145 |
| 63 | Idiopathic thrombocytopenic purpura | 1.098 |
| 50 | Dermatomyositis | 1.067 |
| 235 | Hypoparathyroidism | 1.049 |
| 71 | Idiopathic osteonecrosis of the femoral head | 1.049 |
| 35 | Pemphigus | 1.047 |
| 137 | Focal cortical dysplasia | 1.000 |
| 192 | Cockayne syndrome | 1.000 |
| 277 | Lymphangiomatosis | 1.000 |
| 281 | Klippel-Trenaunay-Weber syndrome | 1.000 |
| 220 | Rapidly progressive glomerulonephritis | 1.000 |
| 30 | Distal myopathy | 1.000 |