Mesenchymal stem cell based therapy for the treatment of osteogenesis imperfecta
Mesenchymal stem cell based therapy for the treatment of osteogenesis imperfecta - TERCELOI
Osteogenesis imperfecta (OI) is a rare genetic disorder with increased bone fragility of varying severity. In the majority of patients the disease is caused by mutations in collagen type I. Severe OI is characterized by osteopenia, frequent fractures, progressive deformity, short stature, loss of mobility, chronic pain and can lead to premature death. At present a cure does not exist.;Therapeutic area: Body processes [G] - Cell Physiological Phenomena [G04] Osteogenesis imperfecta (OI) is a rare genetic disorder with increased bone fragility of varying sev ...