13. Multiple sclerosis/Neuromyelitis optica Clinical trials / Disease details

Clinical trials : 3,340 / Drugs : 2,163 - (DrugBank : 383) / Drug target genes : 241 - Drug target pathways : 238

20 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-005947-22-IT (EUCTR)	17/11/2021	12/10/2021	Effect of siponimod on progressive multiple sclerosis	Effect of siponimod on relevant imaging and immunological hallmarks of progressive multiple sclerosi ...	Active progressive MS course after an initial relapse clinical course MedDRA version: 21.1;Level: PT ...	Product Name: Siponimod 2 mg Product Code: [Siponimod] INN or Proposed INN: Siponimod Product Name: Sipo ...	AZIENDA OSPEDALIERA UNIVERSITARIA INTEGRATA VERONA	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	60	Phase 4	Italy
2	EUCTR2012-003056-36-FR (EUCTR)	06/10/2015	19/06/2013	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 16.0;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530		United States;Portugal;Estonia;Slovakia;Greece;Spain;Ireland;Israel;Russian Federation;Switzerland;I ...
3	EUCTR2012-003056-36-IE (EUCTR)	31/05/2013	06/09/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	United States;Portugal;Estonia;Slovakia;Greece;Spain;Ireland;Israel;Russian Federation;Switzerland;I ...
4	EUCTR2012-003056-36-GB (EUCTR)	08/04/2013	02/10/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	Portugal;United States;Estonia;Slovakia;Greece;Spain;Ireland;Russian Federation;Israel;Switzerland;I ...
5	EUCTR2012-003056-36-BG (EUCTR)	20/03/2013	06/02/2013	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	Portugal;United States;Estonia;Slovakia;Greece;Spain;Ireland;Russian Federation;Israel;Switzerland;I ...
6	EUCTR2012-003056-36-PL (EUCTR)	18/03/2013	20/12/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	Portugal;United States;Estonia;Slovakia;Greece;Spain;Ireland;Russian Federation;Israel;Switzerland;I ...
7	EUCTR2012-003056-36-BE (EUCTR)	21/01/2013	19/11/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	United States;Portugal;Estonia;Slovakia;Greece;Spain;Ireland;Israel;Russian Federation;Switzerland;I ...
8	EUCTR2012-003056-36-GR (EUCTR)	15/01/2013	23/10/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	United States;Portugal;Estonia;Slovakia;Greece;Spain;Ireland;Israel;Russian Federation;Switzerland;I ...
9	EUCTR2012-003056-36-LT (EUCTR)	21/12/2012	29/10/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 21.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530	Phase 3	Portugal;United States;Estonia;Slovakia;Greece;Spain;Ireland;Russian Federation;Israel;Switzerland;I ...
10	EUCTR2012-003056-36-LV (EUCTR)	18/12/2012	18/10/2012	Study of efficacy, safety and tolerability data for BAF312 compared to placebo in patients with seco ...	A multicenter, randomized, double-blind, parallel-group, placebo-controlled variable treatment durat ...	Secondary progressive multiple sclerosis MedDRA version: 14.1;Level: PT;Classification code 10063400 ...	Product Name: Siponimod 2 mg tablet Product Code: BAF312A INN or Proposed INN: Siponimod Other descripti ...	Novartis Pharma Services AG	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	1530		United States;Portugal;Estonia;Slovakia;Greece;Spain;Ireland;Israel;Russian Federation;Switzerland;I ...

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