171. Wilson disease Clinical trials / Disease details

Clinical trials : 79 / Drugs : 77 - (DrugBank : 17) / Drug target genes : 6 - Drug target pathways : 30

21 trials found

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2020-004604-33-PL (EUCTR)	16/11/2021	04/06/2021	Multicentre, open-label study to investigate the effects Cufence has, the effects the body has on Cu ...	Open label, Multicenter, Prospective Study to Characterize the Pharmacokinetics and Pharmacodynamics ...	Wilson Disease MedDRA version: 22.1;Level: PT;Classification code 10019819;Term: Hepato-lenticular d ...	Trade Name: Cufence (trientine dihydrochloride) Product Name: Cufence (trientine dihydrochloride) INN or ...	Univar Solutions, B.V.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	50	Phase 4	Poland;Denmark;Germany
2	EUCTR2020-004604-33-DK (EUCTR)	08/10/2021	11/03/2021	Multicentre, open-label study to investigate the effects Cufence has, the effects the body has on Cu ...	Open label, Multicenter, Prospective Study to Characterize the Pharmacokinetics and Pharmacodynamics ...	Wilson Disease MedDRA version: 22.1;Level: PT;Classification code 10019819;Term: Hepato-lenticular d ...	Trade Name: Cufence (trientine dihydrochloride) Product Name: Cufence (trientine dihydrochloride) INN or ...	Univar Solutions, B.V.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	50	Phase 4	Poland;Denmark;Germany
3	EUCTR2020-005832-31-DK (EUCTR)	13/04/2021	01/02/2021	The effect of ALXN1840 on uptake of copper in the liver as measured by copper PET/CT scan.	Efficacy of ALXN1840 on human hepatic copper uptake quantified with 64CuCl2 PET/CT-scan. - ALXN1840- ...	Healthy Volunteers (Wilson's disease) MedDRA version: 22.0;Level: SOC;Classification code 10022891;T ...	Trade Name: Cuprior 150 mg INN or Proposed INN: TRIENTINE DIHYDROCHLORIDE Other descriptive name: Cuprio ...	Alexion Pharmaceuticals Inc.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	32	Phase 2	Denmark
4	EUCTR2020-004604-33-DE (EUCTR)	23/02/2021	17/12/2020	Multicentre, open-label study to investigate the effects Cufence has, the effects the body has on Cu ...	Open label, Multicenter, Prospective Study to Characterize the Pharmacokinetics and Pharmacodynamics ...	Wilson Disease MedDRA version: 22.1;Level: PT;Classification code 10019819;Term: Hepato-lenticular d ...	Trade Name: Cufence (trientine dihydrochloride) Product Name: Cufence (trientine dihydrochloride) INN or ...	Univar Solutions, B.V.	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	50	Phase 4	France;Poland;Denmark;Germany
5	EUCTR2017-004135-36-NL (EUCTR)	30/03/2020	16/10/2019	Study to Evaluate the Efficacy and Safety of ALXN1840 in pPtients with Wilson Disease.	A Phase 3, Randomized, Rater-Blinded, Multi-Center Study To Evaluate The Efficacy And Safety Of ALXN ...	Wilson Disease MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;S ...	Product Name: ALXN1840 INN or Proposed INN: Not applied Other descriptive name: BIS-CHOLINE TETRATHIOM ...	Alexion Pharmaceuticals, Inc	NULL	Not Recruiting			Female: yes Male: yes	180	Phase 3	United States;Portugal;Serbia;Taiwan;Hong Kong;Greece;Spain;Israel;Russian Federation;Colombia;Italy ...
6	EUCTR2017-004135-36-PT (EUCTR)	13/01/2020	26/03/2019	A Phase 3 clinical study to Evaluate the Efficacy and Safety of ALXN1840 in adult and adolescent pat ...	A Phase 3, Randomized, Rater-Blinded, Multi-Center Study To Evaluate The Efficacy And Safety Of ALXN ...	Wilson Disease MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;S ...	Product Name: ALXN1840 INN or Proposed INN: Not applied Other descriptive name: BIS-CHOLINE TETRATHIOM ...	Alexion Pharmaceuticals, Inc	NULL	Not Recruiting			Female: yes Male: yes	180	Phase 3	United States;Portugal;Serbia;Hong Kong;Taiwan;Spain;Israel;Russian Federation;Colombia;France;Denma ...
7	EUCTR2017-004135-36-SE (EUCTR)	29/10/2019	16/04/2019	A Phase 3 clinical study to Evaluate the Efficacy and Safety of ALXN1840 in adult and adolescent pat ...	A Phase 3, Randomized, Rater-Blinded, Multi-Center Study To Evaluate The Efficacy And Safety Of ALXN ...	Wilson Disease MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;S ...	Product Name: ALXN1840 INN or Proposed INN: Not applied Other descriptive name: BIS-CHOLINE TETRATHIOM ...	Alexion Pharmaceuticals, Inc	NULL	Not Recruiting			Female: yes Male: yes	180	Phase 3	Serbia;United States;Portugal;Taiwan;Hong Kong;Spain;Russian Federation;Israel;Colombia;France;Austr ...
8	EUCTR2017-004135-36-DK (EUCTR)	16/10/2019	05/08/2019	A Phase 3 clinical study to Evaluate the Efficacy and Safety of ALXN1840 in adult and adolescent pat ...	A Phase 3, Randomized, Rater-Blinded, Multi-Center Study To Evaluate The Efficacy And Safety Of ALXN ...	Wilson Disease MedDRA version: 20.0;Level: LLT;Classification code 10047988;Term: Wilson's disease;S ...	Product Name: ALXN1840 INN or Proposed INN: tiomolibdic acid Other descriptive name: BIS-CHOLINE TETRA ...	Alexion Pharmaceuticals, Inc	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	180	Phase 3	Serbia;United States;Portugal;Taiwan;Hong Kong;Spain;Israel;Russian Federation;Colombia;France;Austr ...
9	EUCTR2017-004135-36-FR (EUCTR)	14/09/2018	15/01/2018	A Phase 3 clinical study to Evaluate the Efficacy and Safety of WTX101 in adult patients who suffer ...	A Phase 3, Randomised, Rater-Blinded, Multi-Centre Study to Evaluate the Efficacy and Safety of WTX1 ...	Wilson Disease;Therapeutic area: Body processes [G] - Metabolic Phenomena [G03]	Product Name: WTX101 Product Code: WTX101 INN or Proposed INN: Not applied Other descriptive name: BIS- ...	Wilson Therapeutics AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	102	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): no Therapeutic confirmatory - (P ...	United States;Portugal;Spain;Austria;Israel;United Kingdom;Italy;France;Czech Republic;Hungary;Belgi ...
10	EUCTR2017-004135-36-ES (EUCTR)	27/04/2018	22/01/2018	A Phase 3 clinical study to Evaluate the Efficacy and Safety of WTX101 in adult patients who suffer ...	A Phase 3, Randomised, Rater-Blinded, Multi-Centre Study to Evaluate the Efficacy and Safety of WTX1 ...	Wilson Disease;Therapeutic area: Body processes [G] - Metabolic Phenomena [G03]	Product Name: WTX101 Product Code: WTX101 INN or Proposed INN: Not applied Other descriptive name: BIS- ...	Wilson Therapeutics AB	NULL	Authorised-recruitment may be ongoing or finished			Female: yes Male: yes	102	Phase 3	France;United States;Hungary;Czech Republic;Poland;Spain;Austria;Israel;Germany;Italy;United Kingdom ...

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