Acthar ( DrugBank: - )
9 diseases
| 告示番号 | 疾患名（ページ内リンク） | 臨床試験数 |
|---|---|---|
| 2 | 筋萎縮性側索硬化症 | 2 |
| 13 | 多発性硬化症／視神経脊髄炎 | 12 |
| 14 | 慢性炎症性脱髄性多発神経炎／多巣性運動ニューロパチー | 1 |
| 46 | 悪性関節リウマチ | 7 |
| 49 | 全身性エリテマトーデス | 4 |
| 50 | 皮膚筋炎／多発性筋炎 | 3 |
| 66 | IgA腎症 | 2 |
| 84 | サルコイドーシス | 7 |
| 222 | 一次性ネフローゼ症候群 | 6 |
2. 筋萎縮性側索硬化症
臨床試験数 : 645 / 薬物数 : 589 - (DrugBank : 163) / 標的遺伝子数 : 150 - 標的パスウェイ数 : 225
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03068754 (ClinicalTrials.gov) | June 22, 2017 | 23/2/2017 | Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS) | A Multicenter, Double Blind, Placebo Controlled Study to Assess the Efficacy and Safety of H.P. Acthar® Gel in the Treatment of Subjects With Amyotrophic Lateral Sclerosis | Amyotrophic Lateral Sclerosis | Drug: Acthar;Drug: Placebo | Mallinckrodt | NULL | Terminated | 18 Years | 75 Years | All | 143 | Phase 2/Phase 3 | United States;Argentina;Canada;Chile;Colombia;Mexico;Peru |
| 2 | NCT01906658 (ClinicalTrials.gov) | July 2013 | 15/7/2013 | A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis | A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral Sclerosis | Amyotrophic Lateral Sclerosis | Drug: Repository corticotropin injection | Mallinckrodt | NULL | Completed | 18 Years | 80 Years | All | 43 | Phase 2 | United States |
13. 多発性硬化症／視神経脊髄炎
臨床試験数 : 3,340 / 薬物数 : 2,163 - (DrugBank : 383) / 標的遺伝子数 : 241 - 標的パスウェイ数 : 238
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03126760 (ClinicalTrials.gov) | May 22, 2017 | 4/4/2017 | Pilot Study to Assess the Efficacy & Safety of H.P. Acthar® Gel in Subjects With Relapsing-remitting Multiple Sclerosis | A Multicenter, Randomized, Double Blind, Placebo Controlled Parallel Group, Pilot Study to Assess the Efficacy and Safety of H.P. Acthar® Gel in Subjects With Relapsing-remitting Multiple Sclerosis | Relapsing, Remitting Multiple Sclerosis | Drug: Repository Corticotropin Injection;Drug: Placebo | Mallinckrodt | NULL | Terminated | 18 Years | N/A | All | 35 | Phase 4 | United States |
| 2 | NCT03021317 (ClinicalTrials.gov) | February 2017 | 12/1/2017 | Effects of ACTHAR on Advanced MRI Surrogate Markers of Disease Activity and on Comprehensive Immune Signature During MS Relapses | Effects of ACTHAR on Advanced MRI Surrogate Markers of Disease Activity and on Comprehensive Immune Signature During MS Relapses | Multiple Sclerosis | Drug: ACTHar | University of Chicago | NULL | Not yet recruiting | 18 Years | N/A | All | 18 | Phase 4 | NULL |
| 3 | NCT02446886 (ClinicalTrials.gov) | June 2016 | 7/5/2015 | Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS | Adrenocorticotropic Hormone (ACTH) Effects on Myelination in Subjects With MS | Multiple Sclerosis | Drug: Adrenocorticotropic hormone (ACTH) gel (H.P. Acthar®) | Weill Medical College of Cornell University | Mallinckrodt | Completed | 18 Years | N/A | All | 15 | Phase 4 | United States |
| 4 | NCT02315872 (ClinicalTrials.gov) | May 22, 2015 | 9/12/2014 | ACTH for Fatigue in Multiple Sclerosis Patients | The Effect of ACTH (Acthar) on Measures of Chronic Fatigue in Patients With Relapsing Multiple Sclerosis. | Multiple Sclerosis, Relapsing-Remitting | Drug: ACTH;Drug: Placebo | Providence Health & Services | Mallinckrodt | Completed | 18 Years | 65 Years | All | 8 | Phase 3 | United States |
| 5 | NCT02258217 (ClinicalTrials.gov) | June 2014 | 2/10/2014 | Tolerability of Acthar for the Treatment of Multiple Sclerosis in Relapses (TAMS) | Tolerability of Acthar for the Treatment of Multiple Sclerosis Relapses (TAMS) | Relapsing Remitting Multiple Sclerosis | Drug: Acthar | OhioHealth | NULL | Completed | 18 Years | N/A | All | 30 | N/A | United States |
| 6 | NCT01906684 (ClinicalTrials.gov) | August 2013 | 19/7/2013 | Comprehensive Analysis of Relapse in Multiple Sclerosis | Comprehensive Analysis of Relapse in Multiple Sclerosis | Multiple Sclerosis | Drug: Acthar Gel | Tanner Foundation for Multiple Sclerosis | Questcor Pharmaceuticals, Inc.;Auburn University MRI Research Center;iReportoire Inc | Not yet recruiting | 19 Years | 65 Years | Both | 20 | N/A | United States |
| 7 | NCT02290444 (ClinicalTrials.gov) | August 2013 | 23/10/2014 | Effects of Acthar on Recovery From Cognitive Relapses in MS | Effects of Adrenocorticotropic Hormone (ACTHAR Gel) on Recovery From Cognitive Relapses in Multiple Sclerosis | Multiple Sclerosis | Drug: Adrenocorticotropic Hormone | State University of New York at Buffalo | NULL | Completed | 18 Years | 65 Years | All | 64 | Phase 3 | United States |
| 8 | NCT01900093 (ClinicalTrials.gov) | July 2013 | 11/7/2013 | Evaluation of the Response to Acthar Gel Therapy in Patients Who Failed Intravenous Methylprednisolone (IVMP) for MS Relapses | An Open-Label Prospective Proof-Of-Concept Trial to Evaluate the Response to Acthar Gel Therapy in Patients With Multiple Sclerosis (MS) Relapses Who Have Failed To Make an Adequate Recovery After Treatment With High-Dose Intravenous Methylprednisolone | Multiple Sclerosis | Drug: Acthar Gel | Aaron Miller | Mallinckrodt | Recruiting | 18 Years | 65 Years | All | 10 | N/A | United States |
| 9 | NCT01838174 (ClinicalTrials.gov) | May 2013 | 18/4/2013 | A Trial of Neuroprotection With ACTH in Acute Optic Neuritis | A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis | Multiple Sclerosis | Drug: ACTHAR Gel (ACTH);Drug: IV methylprednisolone (steroids) | University of Colorado, Denver | Mallinckrodt;University of Pennsylvania | Terminated | 18 Years | 55 Years | All | 100 | Phase 4 | United States |
| 10 | NCT01888354 (ClinicalTrials.gov) | April 2013 | 16/5/2013 | Pilot Clinical Trial of ACTHar Gel 14 Days Subcutaneous (SQ)Versus ACTHar Gel Five Days SQ for the Treatment of MS Exacerbations | Pilot Clinical Trial of ACTHar Gel 14 Days Subcutaneous (SQ) Versus ACTHar Gel Five Days SQ for the Treatment of MS Exacerbations | Multiple Sclerosis (MS) | Drug: H.P. Acthar Gel (repository corticotropin injection) | The University of Texas Health Science Center, Houston | NULL | Completed | 18 Years | 55 Years | Both | 25 | Phase 4 | United States |
| 11 | NCT01049451 (ClinicalTrials.gov) | November 2009 | 13/1/2010 | Pulse ACTH vs. MP for MS | Comparison of Monthly Pulse ACTH (Acthar Gel) Therapy With Methylprednisolone (MP, Solumedrol) for Long-Term Treatment of Multiple Sclerosis (MS) as an Add on Therapy to Beta-interferons (Avonex, Betaseron or Rebif) | Multiple Sclerosis | Drug: ACTH;Drug: Methylprednisolone | University of Southern California | NULL | Completed | 18 Years | 65 Years | All | 23 | Phase 1 | United States |
| 12 | NCT00854750 (ClinicalTrials.gov) | May 2009 | 27/2/2009 | Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis | Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis | Multiple Sclerosis | Drug: ACTHAR | Elliot Frohman | Questcor Pharmaceuticals, Inc. | Terminated | 18 Years | 65 Years | Both | 1 | Phase 4 | United States |
14. 慢性炎症性脱髄性多発神経炎／多巣性運動ニューロパチー
臨床試験数 : 175 / 薬物数 : 161 - (DrugBank : 41) / 標的遺伝子数 : 13 - 標的パスウェイ数 : 24
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02574962 (ClinicalTrials.gov) | August 2015 | 30/8/2015 | Pilot Study of Acthar® Gel in Chronic Inflammatory Demyelinating Neuropathy | Pilot Study of Acthar® Gel in Chronic Inflammatory Demyelinating Neuropathy | Chronic Inflammatory Demyelinating Polyneuropathy | Drug: H.P. Acthar® Gel | Mamatha Pasnoor, MD | Mallinckrodt | Withdrawn | 18 Years | N/A | Both | 0 | Phase 2 | United States |
46. 悪性関節リウマチ
臨床試験数 : 4,356 / 薬物数 : 2,567 - (DrugBank : 415) / 標的遺伝子数 : 192 - 標的パスウェイ数 : 228
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03511625 (ClinicalTrials.gov) | October 2, 2018 | 10/4/2018 | The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis | The Effects of Acthar on Synovial Inflammation in Rheumatoid Arthritis: A Pilot Study | Rheumatoid Arthritis | Drug: Acthar Injectable Product;Drug: Depo medrol | Attune Health Research, Inc. | Mallinckrodt | Active, not recruiting | 18 Years | N/A | All | 6 | Phase 3 | United States |
| 2 | NCT02541955 (ClinicalTrials.gov) | July 20, 2017 | 1/9/2015 | Use of Acthar in Rheumatoid Arthritis (RA) Related Flares | Use of Acthar in Rheumatoid Arthritis Related Flares | Rheumatoid Arthritis (RA) | Drug: Acthar | Veena Ranganath, MD, MS | NULL | Recruiting | 18 Years | N/A | All | 40 | Phase 4 | United States |
| 3 | NCT03082573 (ClinicalTrials.gov) | March 3, 2017 | 13/3/2017 | Efficacy, Radiographic and Laboratory Changes in Refractory Rheumatoid Arthritis Patients Treated With H.P. Acthar Gel | Open-label, Pilot Protocol of Patients With Rheumatoid Arthritis Who Were Treated With H.P. Acthar Gel After an Incomplete Response to Combinations of DMARDs and Biologic DMRADs | Rheumatoid Arthritis | Drug: H.P. Acthar gel | Iraj Sabahi Research Inc. | Mallinckrodt | Recruiting | 21 Years | N/A | All | 30 | Phase 4 | United States |
| 4 | NCT02919761 (ClinicalTrials.gov) | November 7, 2016 | 26/9/2016 | Safety and Effectiveness of Acthar Gel in Participants With Rheumatoid Arthritis | A Multicenter, 2 Part Study to Assess the Efficacy and Safety of Acthar Gel in Subjects With Rheumatoid Arthritis With Persistently Active Disease Despite Dual-DMARD Treatment | Arthritis, Rheumatoid | Drug: Acthar Gel;Drug: Placebo | Mallinckrodt | NULL | Completed | 18 Years | N/A | All | 259 | Phase 4 | United States;Argentina;Mexico;Peru;Puerto Rico;Colombia |
| 5 | NCT02030028 (ClinicalTrials.gov) | November 2014 | 6/1/2014 | ACTH Gel Therapy in Rheumatoid Arthritis | Open Label Study to Evaluate Efficacy and Safety of Short-Term, Adjunctive Adrenocorticotropic Hormone (ACTH) Gel in Rheumatoid Arthritis | Rheumatoid Arthritis | Drug: ACTHAR gel | Dana Ascherman | Mallinckrodt | Completed | 18 Years | 100 Years | All | 20 | N/A | United States |
| 6 | NCT01984268 (ClinicalTrials.gov) | June 2014 | 8/11/2013 | ACTHAR for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate | Adenocorticotrophic Hormone for Acute Treatment of Rheumatoid Arthritis Patients With Inadequate Response to Methotrexate | Rheumatoid Arthritis | Drug: ACTHAR | Dartmouth-Hitchcock Medical Center | Mallinckrodt | Recruiting | 18 Years | 70 Years | Both | 60 | Phase 2 | United States |
| 7 | NCT02434757 (ClinicalTrials.gov) | February 2014 | 30/4/2015 | Addition of H.P. Acthar Gel to Treatment Regimen of Patients With Rheumatoid Arthritis | Addition of H. P Acthar Gel to Treatment Regimen of Patients With Rheumatoid Arthritis Inadequately Controlled With Biologic Disease-Modifying Antirheumatic Drugs | Rheumatoid Arthritis | Drug: H.P. Acthar Gel | Ronald J. Rapoport, MD | Questcor Pharmaceuticals, Inc. | Recruiting | 18 Years | N/A | Both | 10 | N/A | United States |
49. 全身性エリテマトーデス
臨床試験数 : 993 / 薬物数 : 702 - (DrugBank : 184) / 標的遺伝子数 : 116 - 標的パスウェイ数 : 200
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02953821 (ClinicalTrials.gov) | December 16, 2016 | 1/11/2016 | Acthar Gel for Active Systemic Lupus Erythematosus (SLE) | A Multicenter, Randomized, Double Blind, Placebo Controlled Study to Assess the Efficacy and Safety of Acthar Gel in Subjects With Persistently Active Systemic Lupus Erythematosus Despite Moderate Dose Corticosteroids | Lupus Erythematosus, Systemic | Drug: Acthar Gel;Drug: Placebo Gel | Mallinckrodt | NULL | Completed | 18 Years | N/A | All | 172 | Phase 4 | United States;Argentina;Chile;Mexico;Peru;Colombia |
| 2 | NCT02779153 (ClinicalTrials.gov) | October 2016 | 18/5/2016 | Acthar SLE (Systemic Lupus Erythematosus) | Efficacy, Safety, and Steroid Sparing Effect of Acthar in Patients With Hematologic Manifestations of Systemic Lupus Erythematosus | Systemic Lupus Erythematosus (SLE);Repository Corticotropin Injection | Drug: Acthar low dose (40 U);Drug: Acthar high dose (80 U) | NYU Langone Health | Mallinckrodt | Withdrawn | 18 Years | N/A | All | 0 | Phase 4 | United States |
| 3 | NCT01753401 (ClinicalTrials.gov) | January 2013 | 17/12/2012 | Acthar for the Treatment of Systemic Lupus Erythematosus (SLE) in Patients With a History of Persistently Active Disease | A Two-part Study Exploring the Efficacy, Safety, and Pharmacodynamics of Acthar in Systemic Lupus Erythematosus Patients With a History of Persistently Active Disease | Systemic Lupus Erythematosus (SLE) | Drug: Acthar;Drug: Placebo;Drug: Steroid Drug | Mallinckrodt | NULL | Completed | 18 Years | N/A | All | 38 | Phase 4 | United States |
| 4 | NCT01769937 (ClinicalTrials.gov) | October 2012 | 15/1/2013 | Open-label Trial of Acthar Gel in Subjects With Moderate to Severe Active Systemic Lupus Erythematosus | A Single-site, Investigator Initiated Open-Label Trial of H.P. Acthar Gel (Repository Corticotropin Injection)an Adrenocorticotropic Hormone (ACTH) Analogue in Subjects With Moderately to Severely Active Systemic Lupus Erythematosus (SLE) | Lupus Erythematosus Systemic Exacerbation | Drug: H.P. Acthar Gel | Fiechtner, Justus J., M.D., P.C. | NULL | Completed | 18 Years | 75 Years | Both | 10 | Phase 4 | United States |
50. 皮膚筋炎／多発性筋炎
臨床試験数 : 194 / 薬物数 : 244 - (DrugBank : 89) / 標的遺伝子数 : 50 - 標的パスウェイ数 : 151
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02245841 (ClinicalTrials.gov) | June 15, 2015 | 11/9/2014 | Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis | Efficacy and Safety of H.P. Acthar Gel for the Treatment of Refractory Cutaneous Manifestations of Dermatomyositis | Dermatomyositis;Juvenile Dermatomyositis | Drug: H.P. Acthar Gel | The Cleveland Clinic | Mallinckrodt | Completed | 18 Years | N/A | All | 15 | Phase 4 | United States |
| 2 | NCT01906372 (ClinicalTrials.gov) | September 2013 | 5/7/2013 | Acthar in Treatment of Refractory Dermatomyositis and Polymyositis | Open Label Proof of Concept Study to Evaluate Efficacy and Safety of Adrenocorticotropic Hormone Gel in Refractory Dermatomyositis or Polymyositis | Dermatomyositis;Polymyositis | Drug: Adrenocorticotropic Hormone Gel | Rohit Aggarwal, MD | Mallinckrodt | Completed | 18 Years | N/A | All | 12 | Phase 2 | United States |
| 3 | NCT01637064 (ClinicalTrials.gov) | April 2013 | 6/7/2012 | Dermatomyositis and Polymyositis Registry | Acthar Dermatomyositis and Polymyositis Treatment | Dermatomyositis;Polymyositis | Drug: Acthar | Phoenix Neurological Associates, LTD | NULL | Enrolling by invitation | 18 Years | 85 Years | Both | 100 | N/A | United States |
66. IgA腎症
臨床試験数 : 275 / 薬物数 : 258 - (DrugBank : 82) / 標的遺伝子数 : 36 - 標的パスウェイ数 : 140
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02282930 (ClinicalTrials.gov) | March 2015 | 31/10/2014 | Pilot Study of ACTH in the Treatment of Immunoglobulin A (IgA) Nephropathy at High Risk of Progression | An Open-Label Pilot Study of ACTH in the Treatment of IgA Nephropathy at High Risk of Progression | Progressive IgA Nephropathy;Proteinuria | Drug: ACTH (Acthar) Gel | Mayo Clinic | Mallinckrodt | Completed | 18 Years | N/A | All | 20 | Phase 3 | United States |
| 2 | NCT02382523 (ClinicalTrials.gov) | February 2015 | 9/1/2015 | Acthar on Proteinuria in IgA Nephropathy Patients | Impact of Acthar on Proteinuria and Disease Progression in IgA Nephropathy Patients With Nephrotic Range Proteinuria | IgA Nephropathy;Proteinuria | Drug: Acthar 80 unit injection | Baylor College of Medicine | NULL | Withdrawn | 18 Years | N/A | All | 0 | Phase 4 | United States |
84. サルコイドーシス
臨床試験数 : 149 / 薬物数 : 202 - (DrugBank : 78) / 標的遺伝子数 : 66 - 標的パスウェイ数 : 169
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02523092 (ClinicalTrials.gov) | October 2020 | 10/8/2015 | Use of CXCL9 as a Biomarker of Acthar Efficacy | Use of CXCL9 as a Biomarker of Acthar Efficacy | Sarcoidosis | Drug: Acthar gel | University of California, San Francisco | Mallinckrodt | Not yet recruiting | 18 Years | 65 Years | All | 14 | Phase 4 | United States |
| 2 | NCT02920710 (ClinicalTrials.gov) | February 1, 2019 | 29/9/2016 | ACTHAR Therapy for Central Nervous System Sarcoidosis | ACTHAR Therapy for Central Nervous System Sarcoidosis | Sarcoidosis | Drug: Repository Corticotropin Injection | The Cleveland Clinic | Mallinckrodt | Withdrawn | N/A | N/A | All | 0 | Phase 4 | United States |
| 3 | NCT03320070 (ClinicalTrials.gov) | February 21, 2018 | 20/10/2017 | Acthar Gel in Participants With Pulmonary Sarcoidosis | A Multicenter, Randomized, Double Blind, Placebo Controlled Exploratory Study to Assess the Efficacy and Safety of Acthar Gel in Subjects With Pulmonary Sarcoidosis | Sarcoidosis, Pulmonary | Drug: Acthar Gel;Drug: Placebo | Mallinckrodt | NULL | Completed | 18 Years | 90 Years | All | 55 | Phase 4 | United States |
| 4 | NCT02298491 (ClinicalTrials.gov) | May 2016 | 14/11/2014 | CNS Sarcoidosis and Acthar Gel | Clinical Biomarkers of Disease Activity and Treatment Responses in Patients With CNS Sarcoidosis Treated With H.P. Acthar Gel | CNS Sarcoidosis | Drug: H.P. Acthar Gel | University of Maryland, Baltimore | Mallinckrodt | Completed | N/A | N/A | All | 4 | Phase 4 | United States |
| 5 | NCT02348905 (ClinicalTrials.gov) | March 2015 | 20/6/2014 | ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial | ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial | Sarcoidosis;Cutaneous Sarcoidosis | Drug: ACTHAR Gel 40 units twice weekly;Drug: ACTHAR Gel 80 units twice weekly. | Albany Medical College | NULL | Not yet recruiting | 18 Years | N/A | Both | 10 | Phase 2/Phase 3 | United States |
| 6 | NCT02155803 (ClinicalTrials.gov) | February 2015 | 30/5/2014 | ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study | ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study | Sarcoidosis;Hypercalcemia Due to Sarcoidosis | Drug: ACTHAR Gel (adrenocorticotropic hormone) | Albany Medical College | NULL | Not yet recruiting | 18 Years | N/A | Both | 10 | Phase 2/Phase 3 | United States |
| 7 | NCT02188017 (ClinicalTrials.gov) | June 2014 | 24/4/2014 | Acthar Gel for Chronic Pulmonary Sarcoidosis (ACPS) | ACTHAR Gel for Chronic Pulmonary Sarcoidosis (ACPS) | Sarcoidosis;Pulmonary Sarcoidosis | Drug: Acthar gel | University of Cincinnati | Mallinckrodt | Recruiting | 18 Years | 90 Years | Both | 20 | Phase 4 | United States |
222. 一次性ネフローゼ症候群
臨床試験数 : 310 / 薬物数 : 295 - (DrugBank : 117) / 標的遺伝子数 : 63 - 標的パスウェイ数 : 194
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT02399462 (ClinicalTrials.gov) | March 2021 | 8/1/2015 | Acthar for Treatment of Post-transplant FSGS | Acthar for Treatment of Post-transplant FSGS | FSGS;Renal Transplantation;Kidney Transplantation | Drug: Acthar | University of North Carolina, Chapel Hill | Mallinckrodt | Withdrawn | 18 Years | N/A | All | 0 | Phase 4 | United States |
| 2 | NCT02683889 (ClinicalTrials.gov) | February 1, 2019 | 5/2/2016 | Use of Acthar in Patients With FSGS That Will be Undergoing Renal Transplantation | The Use of Acthar (ACTH) in Patients With Focal Segmental Glomerulosclerosis (FSGS) Who Have Developed Chronic Kidney Disease Stage V (CKD) or End Stage Renal Disease (ESRD) and Are Undergoing a Renal Transplant | FSGS | Drug: Acthar | University of Colorado, Denver | NULL | Recruiting | 18 Years | 80 Years | All | 20 | Phase 3 | United States |
| 3 | NCT03025828 (ClinicalTrials.gov) | March 19, 2018 | 17/1/2017 | Adrenocorticotropic Hormone in Membranous Nephropathy | Changes in Autoreactive Memory B Cells as Biomarker of Response to Adrenocorticotropic Hormone in Patients With Membranous Nephropathy | Membranous Nephropathy | Drug: ACTHar | Icahn School of Medicine at Mount Sinai | NULL | Completed | 18 Years | 70 Years | All | 5 | Phase 4 | United States |
| 4 | NCT02633046 (ClinicalTrials.gov) | October 10, 2016 | 15/12/2015 | Acthar for Treatment-Resistant or Treatment-Intolerant Proteinuria | Treatment of Proteinuria Due to Treatment Resistant or Treatment Intolerant Idiopathic Focal Segmental Glomerulosclerosis: A Prospective Study of Acthar (PODOCYTE) | Idiopathic Focal Segmental Glomerulosclerosis | Drug: Acthar Gel | Mallinckrodt ARD LLC | NULL | Completed | 18 Years | N/A | All | 63 | Phase 4 | United States;Argentina;Australia;Chile;Mexico;Peru;Turkey;Canada;Hong Kong;New Zealand;Puerto Rico |
| 5 | NCT01386554 (ClinicalTrials.gov) | August 2011 | 29/6/2011 | Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients | A Randomized, Placebo-Controlled, Parallel-Group, Double-Blind Study of H.P. Acthar Gel (Acthar) in Treatment-Resistant Subjects With Persistent Proteinuria and Nephrotic Syndrome Due to Idiopathic Membranous Nephropathy (iMN) | Proteinuria;Idiopathic Membranous Nephropathy | Drug: Repository Corticotropin Injection;Drug: Placebo | Mallinckrodt | NULL | Completed | 18 Years | N/A | All | 60 | Phase 4 | United States;Canada;Chile;Mexico;Turkey |
| 6 | NCT01155141 (ClinicalTrials.gov) | September 2009 | 29/6/2010 | Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTH | Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTH | Kidney Diseases | Drug: H.P. Acthar Gel | Stanford University | Mallinckrodt | Completed | 16 Years | 65 Years | All | 15 | Phase 4 | United States |