Isotretinoin ( DrugBank: Isotretinoin )

4 diseases

ID	Disease name (Link within this page)	Number of trials
36	Epidermolysis bullosa	1
39	Toxic epidermal necrolysis	1
159	Xeroderma pigmentosum	1
160	Congenital ichthyosis	1

36. Epidermolysis bullosa

Clinical trials : 163 / Drugs : 185 - (DrugBank : 46) / Drug target genes : 50 - Drug target pathways : 125

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00014729 (ClinicalTrials.gov)	October 2000	10/4/2001	Phase I Study of Isotretinoin in Patients With Recessive Dystrophic Epidermolysis Bullosa		Epidermolysis Bullosa	Drug: isotretinoin	University of North Carolina	NULL	Completed	15 Years	N/A	Both	20	Phase 1	NULL

Clinical trials : 13 / Drugs : 19 - (DrugBank : 8) / Drug target genes : 11 - Drug target pathways : 103

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02795143 (ClinicalTrials.gov)	November 2016	6/6/2016	Evaluating the Effect of Isotretinoinin Regulatory T-cell Function in Adverse Cutaneous Drug Eruptio ...	Evaluating the Effect of Isotretinoinin Regulatory T-cell Function in Adverse Cutaneous Drug Eruptio ...	Toxic Epidermal Necrolysis	Drug: Isotretinoin;Other: Placebo	Massachusetts General Hospital	NULL	Recruiting	18 Years	69 Years	Both	40	N/A	United States

Clinical trials : 11 / Drugs : 17 - (DrugBank : 5) / Drug target genes : 5 - Drug target pathways : 15

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00025012 (ClinicalTrials.gov)	June 1991	11/10/2001	Isotretinoin in Preventing Skin Cancer	Use Of Isotretinion For Prevention Of Skin Cancer In Patients With Xeroderma Pigmentosum Or Nevoid B ...	Melanoma (Skin);Non-melanomatous Skin Cancer	Drug: isotretinoin	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)	NULL	Completed	2 Years	N/A	Both		N/A	United States

Clinical trials : 42 / Drugs : 71 - (DrugBank : 21) / Drug target genes : 18 - Drug target pathways : 112

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04154293 (ClinicalTrials.gov)	December 3, 2019	1/11/2019	A Vehicle Controlled Study to Evaluate Safety and Efficacy of Topical TMB-001 for Treatment of Conge ...	A Randomized, Parallel, Double-Blind, Vehicle Controlled Study to Evaluate the Safety and Efficacy o ...	Congenital Ichthyosis	Drug: Isotretinoin;Other: Vehicle	Timber Pharmceuticals LLC	NULL	Completed	9 Years	N/A	All	34	Phase 2	United States;Australia