Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 Acute myeloid leukemia 💬
 [1] RARA 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
2 Autoimmune thyroid disease 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
3 Cell adhesion molecules 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
4 Cell adhesion molecules 💬
 [1] PDCD1 💬 Nivolumab 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
5 Estrogen signaling pathway 💬
 [1] RARA 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
6 Gastric cancer 💬
 [1] RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
7 Melanogenesis 💬
 [1] MC1R 💬 Afamelanotide 💬 Afamelanotide [3] 159, 161, 254 💬
8 Neuroactive ligand-receptor interaction 💬
 [1] MC1R 💬 Afamelanotide 💬 Afamelanotide [3] 159, 161, 254 💬
9 Non-small cell lung cancer 💬
 [1] RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
10 Pathways in cancer 💬
 [2] RARA, RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
11 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [1] PDCD1 💬 Nivolumab 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
12 Rheumatoid arthritis 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
13 Small cell lung cancer 💬
 [1] RARB 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
14 T cell receptor signaling pathway 💬
 [1] CTLA4 💬 Ipilimumab 💬 Ipilimumab [1] 159 💬
15 T cell receptor signaling pathway 💬
 [1] PDCD1 💬 Nivolumab 💬 Nivolumab [12] 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
16 Th17 cell differentiation 💬
 [1] RARA 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬
17 Transcriptional misregulation in cancer 💬
 [1] RARA 💬 Isotretinoin 💬 Isotretinoin [4] 36, 39, 159, 160 💬

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