NNC 0151-0000-0000 ( DrugBank: - )

2 diseases

ID	Disease name (Link within this page)	Number of trials
46	Malignant rheumatoid arthritis	6
49	Systemic lupus erythematosus	2

46. Malignant rheumatoid arthritis

Clinical trials : 4,356 / Drugs : 2,567 - (DrugBank : 415) / Drug target genes : 192 - Drug target pathways : 228

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2009-011791-30-HU (EUCTR)	14/03/2012	19/01/2012	A multiple dose trial of NNC 0151-0000-0000 in subjects with rheumatoid arthritis	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC0151-0000-0000 in subjects ...	Rheumatoid arthritis MedDRA version: 14.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: NNC151-0000 Product Code: NNC0151-0000-0000 Other descriptive name: Anti-C5aR	Novo Nordisk A/S	NULL	Not Recruiting			Female: yes Male: yes	48		Czech Republic;Hungary;Poland;Ukraine;Romania;Denmark;Russian Federation;Germany;United Kingdom
2	NCT01223911 (ClinicalTrials.gov)	January 2011	14/10/2010	A Multiple Dose Trial of NNC 0151-0000-0000 in Subjects With Rheumatoid Arthritis	A Randomised, Double-blind, Placebo-controlled, Multiple Dose Trial of NNC 0151-0000-0000in Subjects ...	Inflammation;Rheumatoid Arthritis	Drug: NNC 0151-0000-0000;Drug: placebo	Novo Nordisk A/S	NULL	Completed	18 Years	75 Years	All	34	Phase 2	Czech Republic;Denmark;Hungary;Poland;Romania;United Kingdom
3	EUCTR2009-011791-30-CZ (EUCTR)	18/11/2010	02/08/2010	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	Rheumatoid arthritis MedDRA version: 15.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: NNC151-0000 Product Code: NNC0151-0000-0000 Other descriptive name: Anti-C5aR	Novo Nordisk A/S	NULL	Not Recruiting			Female: yes Male: yes	48		Hungary;Czech Republic;Poland;Ukraine;Romania;Denmark;Russian Federation;Germany;United Kingdom
4	EUCTR2009-011791-30-DK (EUCTR)	22/09/2010	12/11/2009	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	Rheumatoid arthritis MedDRA version: 14.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: NNC151-0000 Product Code: NNC0151-0000-0000 Other descriptive name: Anti-C5aR	Novo Nordisk A/S	NULL	Not Recruiting			Female: yes Male: yes	48		Hungary;Czech Republic;Poland;Ukraine;Romania;Denmark;Russian Federation;Germany;United Kingdom
5	EUCTR2009-011791-30-GB (EUCTR)	14/04/2010	14/10/2009	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	A randomised, double-blind, placebo-controlled, multiple dose trial of NNC 0151-0000-0000in subjects ...	Rheumatoid arthritis MedDRA version: 14.1;Level: PT;Classification code 10039073;Term: Rheumatoid ar ...	Product Name: NNC151-0000 Product Code: NNC0151-0000-0000 Other descriptive name: Anti-C5aR	Novo Nordisk A/S	NULL	Not Recruiting			Female: yes Male: yes	48	Human pharmacology (Phase 1): no Therapeutic exploratory (Phase 2): yes Therapeutic confirmatory - ( ...	Hungary;Czech Republic;Poland;Ukraine;Romania;Denmark;Russian Federation;Germany;United Kingdom
6	NCT02151409 (ClinicalTrials.gov)	June 2008	28/5/2014	Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects	A Randomised, Double-blind, Placebo-controlled, Single-dose, Dose-escalation Trial of Anti-C5aR Anti ...	Inflammation;Systemic Lupus Erythematosus;Rheumatoid Arthritis;Healthy	Drug: NNC 0151-0000-0000;Drug: placebo	Novo Nordisk A/S	NULL	Completed	18 Years	55 Years	Male	60	Phase 1	Netherlands

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49. Systemic lupus erythematosus

Clinical trials : 993 / Drugs : 702 - (DrugBank : 184) / Drug target genes : 116 - Drug target pathways : 200

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01018238 (ClinicalTrials.gov)	November 2009	16/11/2009	An Investigation of NNC 0151-0000-0000 in Subjects With Systemic Lupus Erythematosus (SLE)	A Multiple Dose, Randomised, Double-blind, Placebo-controlled, Multiple Site Study of Anti-C5a Recep ...	Inflammation;Systemic Lupus Erythematosus	Drug: NNC 0151-0000-0000;Drug: placebo	Novo Nordisk A/S	NULL	Withdrawn	18 Years	65 Years	Both	0	Phase 1	United States
2	NCT02151409 (ClinicalTrials.gov)	June 2008	28/5/2014	Dose-escalation Trial of Anti-C5aR Antibody in Healthy Subjects	A Randomised, Double-blind, Placebo-controlled, Single-dose, Dose-escalation Trial of Anti-C5aR Anti ...	Inflammation;Systemic Lupus Erythematosus;Rheumatoid Arthritis;Healthy	Drug: NNC 0151-0000-0000;Drug: placebo	Novo Nordisk A/S	NULL	Completed	18 Years	55 Years	Male	60	Phase 1	Netherlands

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