Mecasermin ( DrugBank: Mecasermin )

5 diseases

ID	Disease name (Link within this page)	Number of trials
78	Hypopituitarism	4
96	Crohn disease	1
168	Ehlers-Danlos syndrome	1
265	Lipodystrophy	1
299	Cystic fibrosis	1

78. Hypopituitarism

Clinical trials : 492 / Drugs : 341 - (DrugBank : 47) / Drug target genes : 45 - Drug target pathways : 100

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-020742-10-GB (EUCTR)	09/05/2011	04/11/2010	Recombinant Human Insulin-like Growth Factor (rhIGF-1) and Growth Hormone (rhGH) Combination Therapy ...	Recombinant Human Insulin-like Growth Factor (rhIGF-1) and Growth Hormone (rhGH) Combination Therapy ...	Pre-Pubertal Children with Idiopathic Growth Hormone Deficiency MedDRA version: 12.1;Level: LLT;Clas ...	Trade Name: NutropinAq 10 mg/2 ml INN or Proposed INN: Somatropin Trade Name: INCRELEX 10 mg/ml INN or ...	Ipsen Pharma	NULL	Not Recruiting	Female: yes Male: yes	63	Phase 2	Finland;United Kingdom;Spain;Sweden
2	EUCTR2010-020742-10-ES (EUCTR)	01/04/2011	07/01/2011	Tratamiento combinado con factor de crecimiento insulínico tipo I recombinante (rhIGFI) y hormona de ...	Tratamiento combinado con factor de crecimiento insulínico tipo I recombinante (rhIGFI) y hormona de ...	Niños pre-puberales con déficit idiopático de hormona de crecimiento MedDRA version: 12.1;Level: LLT ...	Trade Name: NUTROPINAq 10 mg/2 ml (30 UI), solución inyectable INN or Proposed INN: SOMATROPINA Other ...	Ipsen Pharma	NULL	Not Recruiting	Female: yes Male: yes	63		Finland;United Kingdom;Spain;Sweden
3	EUCTR2010-020742-10-SE (EUCTR)	23/02/2011	19/11/2010	Comparison of efficacy and safety of Nutropin (rhGH) associated with Increlex (rhIGF-1) vs Nutropin ...	Recombinant Human Insulin-like Growth Factor (rhIGF-1) and Growth Hormone (rhGH) Combination Therapy ...	Pre-Pubertal Children with Idiopathic Growth Hormone Deficiency and with poor response after one yea ...	Trade Name: NutropinAq 10 mg/2 ml INN or Proposed INN: Somatropin Trade Name: INCRELEX 10 mg/ml INN or ...	Ipsen Pharma	NULL	Not Recruiting	Female: yes Male: yes	63	Phase 2	Finland;United Kingdom;Spain;Sweden
4	EUCTR2010-020742-10-FI (EUCTR)	10/01/2011	22/11/2010	Comparison of efficacy and safety of Nutropin (rhGH) associated with Increlex (rhIGF-1) vs Nutropin ...	Recombinant Human Insulin-like Growth Factor (rhIGF-1) and Growth Hormone (rhGH) Combination Therapy ...	Pre-Pubertal Children with Idiopathic Growth Hormone Deficiency and with poor response after one yea ...	Trade Name: NutropinAq 10 mg/2 ml INN or Proposed INN: Somatropin Trade Name: INCRELEX 10 mg/ml INN or ...	Ipsen Pharma	NULL	Not Recruiting	Female: yes Male: yes	63	Phase 2	Finland;United Kingdom;Spain;Sweden

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96. Crohn disease

Clinical trials : 2,442 / Drugs : 1,278 - (DrugBank : 248) / Drug target genes : 142 - Drug target pathways : 209

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2010-022215-19-GB (EUCTR)	21/07/2011	23/06/2011	Combined growth hormone and IGF1 therapy in paediatric Crohn'd disease	A Pharmacokinetic Study Of The Combined Use Of Recombinant Human GH And IGF-1 In Children With Infla ...	Impaired growth in Paediatric Crohn's disease MedDRA version: 14.1;Level: LLT;Classification code 10 ...	Trade Name: Increlex Product Name: Increlex 10mg/ml solution for injection INN or Proposed INN: Mecase ...	Greater Glasgow & Clyde NHS	NULL	Not Recruiting			Female: yes Male: yes	24	Phase 2	United Kingdom

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168. Ehlers-Danlos syndrome

Clinical trials : 13 / Drugs : 21 - (DrugBank : 11) / Drug target genes : 11 - Drug target pathways : 103

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01446783 (ClinicalTrials.gov)	September 2011	27/9/2011	IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos Patients	IGF-I Stimulation of Collagen Synthesis in Ehlers-Danlos Patients	Ehlers-Danlos Syndrome, Classic	Drug: mecasermin;Drug: Saline	Bispebjerg Hospital	NULL	Completed	18 Years	N/A	Both	15	N/A	Denmark

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265. Lipodystrophy

Clinical trials : 112 / Drugs : 155 - (DrugBank : 55) / Drug target genes : 25 - Drug target pathways : 97

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01329744 (ClinicalTrials.gov)	June 2011	4/4/2011	Effects of IGF-I in HIV Metabolic Disease	Effects of Recombinant IGF-I in HIV Associated Metabolic Disease	HIV Lipodystrophy	Drug: mecasermin;Drug: Placebo control	University of Texas Southwestern Medical Center	NULL	Terminated	18 Years	60 Years	Both	16	Phase 1	United States

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299. Cystic fibrosis

Clinical trials : 1,695 / Drugs : 1,527 - (DrugBank : 268) / Drug target genes : 111 - Drug target pathways : 174

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-002719-27-IT (EUCTR)	30/12/2011	13/03/2012	EFFECT OF RECOMBINANT HUMAN INSULIN-LIKE GROWTH FACTOR-I ON GLUCOSE TOLERANCE AND AS PREVENTION TOWA ...	GLUCOSE METABOLISM AND INFLAMMATORY PARAMETERS UNDER IGF-I TREATMENT IN CYSTIC FIBROSIS - RH-IGF-I I ...	PATIENTS WITH CYSTIC FIBROSIS MedDRA version: 14.1;Level: PT;Classification code 10011766;Term: Cyst ...	Trade Name: INCRELEX*SC 1FL 4ML 10MG/ML INN or Proposed INN: MECASERMIN	AZIENDA OSPEDALIERA DI PARMA	NULL	Not Recruiting			Female: yes Male: yes	20		Italy

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