Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank Disease ID
1 ABC transporters 💬
 [1] ABCC8 💬 Repaglinide 💬 Repaglinide [4]  6 , 21, 46, 299 💬
2 ABC transporters 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
3 ABC transporters 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
4 ABC transporters 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
5 ABC transporters 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
6 ABC transporters 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
7 ABC transporters 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
8 Acute myeloid leukemia 💬
 [1] RARA 💬 Fenretinide 💬 Fenretinide [1] 299 💬
9 Adherens junction 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
10 Adherens junction 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
11 Adherens junction 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
12 Adipocytokine signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
13 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
14 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
15 Adrenergic signaling in cardiomyocytes 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
16 Adrenergic signaling in cardiomyocytes 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
17 Adrenergic signaling in cardiomyocytes 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
18 AGE-RAGE signaling pathway in diabetic complications 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
19 Alcoholic liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
20 Alcoholism 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
21 Alcoholism 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
22 Alcoholism 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
23 Aldosterone synthesis and secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
24 Aldosterone synthesis and secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
25 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
26 Aldosterone synthesis and secretion 💬
 [1] PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
27 Aldosterone-regulated sodium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
28 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
29 Aldosterone-regulated sodium reabsorption 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
30 Aldosterone-regulated sodium reabsorption 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
31 Alzheimer disease 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
32 Alzheimer disease 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
33 Alzheimer disease 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
34 Alzheimer disease 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
35 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
36 Alzheimer disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
37 Alzheimer disease 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
38 Amoebiasis 💬
 [2] IL1R1, IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
39 Amphetamine addiction 💬
 [1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
40 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
41 Amphetamine addiction 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
42 AMPK signaling pathway 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
43 AMPK signaling pathway 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
44 AMPK signaling pathway 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
45 AMPK signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
46 AMPK signaling pathway 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
47 AMPK signaling pathway 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
48 AMPK signaling pathway 💬
 [1] HMGCR 💬 Atorvastatin 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
49 AMPK signaling pathway 💬
 [1] HMGCR 💬 Rosuvastatin 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
50 AMPK signaling pathway 💬
 [1] HMGCR 💬 Simvastatin 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
51 AMPK signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
52 AMPK signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
53 AMPK signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
54 AMPK signaling pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
55 AMPK signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
56 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
57 Amyotrophic lateral sclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
58 Apelin signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
59 Apelin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
60 Apelin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
61 Apelin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
62 Apoptosis 💬
 [1] CTSC 💬 Brensocatib 💬 Brensocatib [1] 299 💬
63 Arachidonic acid metabolism 💬
 [2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
64 Asthma 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
65 Autophagy - animal 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
66 Autophagy - animal 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
67 Axon guidance 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
68 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
69 Axon guidance 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
70 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
71 B cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
72 Bile secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
73 Bile secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
74 Bile secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
75 Bile secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
76 Bile secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
77 Bile secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
78 Bile secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
79 Bile secretion 💬
 [1] HMGCR 💬 Atorvastatin 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
80 Bile secretion 💬
 [1] HMGCR 💬 Rosuvastatin 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
81 Bile secretion 💬
 [1] HMGCR 💬 Simvastatin 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
82 Bile secretion 💬
 [1] NR1H4 💬 Ursodiol 💬 Ursodeoxycholic acid [14]  6 ,  8 , 20, 46, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬
83 Breast cancer 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
84 Breast cancer 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
85 Breast cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
86 Breast cancer 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
87 Breast cancer 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
88 Breast cancer 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
89 Breast cancer 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
90 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
91 C-type lectin receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
92 C-type lectin receptor signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
93 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
94 Calcium signaling pathway 💬
 [4] ADORA2B, PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
95 Calcium signaling pathway 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
96 Calcium signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
97 Calcium signaling pathway 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
98 Calcium signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
99 Calcium signaling pathway 💬
 [2] AVPR1A, AVPR1B 💬 Terlipressin 💬 Terlipressin [1] 299 💬
100 Calcium signaling pathway 💬
 [4] CHRM1, CHRM2, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
101 Calcium signaling pathway 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
102 Calcium signaling pathway 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
103 Calcium signaling pathway 💬
 [2] DRD1, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
104 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
105 Calcium signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
106 Calcium signaling pathway 💬
 [1] PTGFR 💬 Tafluprost 💬 Tafluprost [1] 299 💬
107 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
108 cAMP signaling pathway 💬
 [8] ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
109 cAMP signaling pathway 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
110 cAMP signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
111 cAMP signaling pathway 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
112 cAMP signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
113 cAMP signaling pathway 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
114 cAMP signaling pathway 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
115 cAMP signaling pathway 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
116 cAMP signaling pathway 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
117 cAMP signaling pathway 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
118 cAMP signaling pathway 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
119 cAMP signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
120 cAMP signaling pathway 💬
 [1] CHRM2 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
121 cAMP signaling pathway 💬
 [3] DRD1, DRD2, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
122 cAMP signaling pathway 💬
 [1] GLP1R 💬 Dulaglutide 💬 Dulaglutide [2] 13, 299 💬
123 cAMP signaling pathway 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
124 Carbohydrate digestion and absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
125 Cardiac muscle contraction 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
126 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
127 Cellular senescence 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
128 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
129 cGMP-PKG signaling pathway 💬
 [4] ADORA1, PDE2A, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
130 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
131 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
132 cGMP-PKG signaling pathway 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
133 cGMP-PKG signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
134 cGMP-PKG signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
135 cGMP-PKG signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
136 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
137 cGMP-PKG signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
138 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Sildenafil 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
139 cGMP-PKG signaling pathway 💬
 [1] PDE5A 💬 Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬
140 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
141 cGMP-PKG signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
142 Chagas disease 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
143 Chemical carcinogenesis - DNA adducts 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
144 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
145 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
146 Chemical carcinogenesis - receptor activation 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
147 Chemical carcinogenesis - receptor activation 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
148 Chemical carcinogenesis - receptor activation 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
149 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
150 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
151 Chemical carcinogenesis - receptor activation 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
152 Chemical carcinogenesis - receptor activation 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
153 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 Calcifediol 💬 Calcifediol [2] 113, 299 💬
154 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 Cholecalciferol 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
155 Chemical carcinogenesis - receptor activation 💬
 [1] VDR 💬 Ergocalciferol 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
156 Chemokine signaling pathway 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
157 Chemokine signaling pathway 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
158 Cholinergic synapse 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
159 Cholinergic synapse 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
160 Circadian entrainment 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
161 Circadian rhythm 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
162 Cocaine addiction 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
163 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
164 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
165 Collecting duct acid secretion 💬
 [2] ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
166 Complement and coagulation cascades 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬
167 Complement and coagulation cascades 💬
 [1] SERPINC1 💬 Adomiparin 💬 Heparin [11] 47, 60, 70, 84, 107, 224, 226, 280, 299, 316, 317 💬
168 Coronavirus disease - COVID-19 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
169 Cortisol synthesis and secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
170 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
171 Cortisol synthesis and secretion 💬
 [2] PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
172 Cushing syndrome 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
173 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
174 Cushing syndrome 💬
 [3] PDE11A, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
175 Cytokine-cytokine receptor interaction 💬
 [1] CSF2RA 💬 Molgramostim 💬 Molgramostim [3] 97, 229, 299 💬
176 Cytokine-cytokine receptor interaction 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
177 Cytokine-cytokine receptor interaction 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
178 Cytokine-cytokine receptor interaction 💬
 [1] GHR 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
179 Cytokine-cytokine receptor interaction 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
180 Cytokine-cytokine receptor interaction 💬
 [2] IL1R1, IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
181 Cytokine-cytokine receptor interaction 💬
 [1] IL5RA 💬 Benralizumab 💬 Benralizumab [5] 44, 45, 98, 162, 299 💬
182 Cytokine-cytokine receptor interaction 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
183 Diabetic cardiomyopathy 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
184 Diabetic cardiomyopathy 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
185 Diabetic cardiomyopathy 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
186 Dopaminergic synapse 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
187 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
188 Dopaminergic synapse 💬
 [3] PPP3CA, PPP3CB, PPP3CC 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
189 EGFR tyrosine kinase inhibitor resistance 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
190 Endocrine and other factor-regulated calcium reabsorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
191 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
192 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
193 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 Calcifediol 💬 Calcifediol [2] 113, 299 💬
194 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 Cholecalciferol 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
195 Endocrine and other factor-regulated calcium reabsorption 💬
 [1] VDR 💬 Ergocalciferol 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
196 Endocrine resistance 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
197 Endocrine resistance 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
198 Endocrine resistance 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
199 Endocytosis 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
200 Endocytosis 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
201 Endocytosis 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
202 Epithelial cell signaling in Helicobacter pylori infection 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
203 Estrogen signaling pathway 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
204 Estrogen signaling pathway 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
205 Estrogen signaling pathway 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
206 Estrogen signaling pathway 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
207 Estrogen signaling pathway 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
208 Estrogen signaling pathway 💬
 [1] RARA 💬 Fenretinide 💬 Fenretinide [1] 299 💬
209 Fc epsilon RI signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
210 Fluid shear stress and atherosclerosis 💬
 [2] IL1R1, IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
211 Fluid shear stress and atherosclerosis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
212 Focal adhesion 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
213 FoxO signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
214 FoxO signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
215 FoxO signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
216 FoxO signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
217 GABAergic synapse 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
218 Gap junction 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
219 Gap junction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
220 Gastric acid secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
221 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
222 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
223 Gastric acid secretion 💬
 [2] ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
224 Gastric acid secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
225 Gastric acid secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
226 Gastric acid secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
227 Gastric acid secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
228 Gastric acid secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
229 Gastric acid secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
230 Gastric acid secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
231 Gastric acid secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
232 Gastric cancer 💬
 [1] RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬
233 Glioma 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
234 Glucagon signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
235 Glucagon signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
236 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
237 Glucagon signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
238 Glucagon signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
239 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
240 Glutamatergic synapse 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
241 GnRH secretion 💬
 [1] ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
242 GnRH secretion 💬
 [1] KCNJ11 💬 Repaglinide 💬 Repaglinide [4]  6 , 21, 46, 299 💬
243 Growth hormone synthesis, secretion and action 💬
 [1] GHR 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
244 Hematopoietic cell lineage 💬
 [1] CSF2RA 💬 Molgramostim 💬 Molgramostim [3] 97, 229, 299 💬
245 Hematopoietic cell lineage 💬
 [2] IL1R1, IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
246 Hematopoietic cell lineage 💬
 [1] IL5RA 💬 Benralizumab 💬 Benralizumab [5] 44, 45, 98, 162, 299 💬
247 Hepatocellular carcinoma 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
248 Herpes simplex virus 1 infection 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
249 HIF-1 signaling pathway 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
250 HIF-1 signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
251 HIF-1 signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
252 HIF-1 signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
253 Human cytomegalovirus infection 💬
 [1] CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
254 Human cytomegalovirus infection 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
255 Human cytomegalovirus infection 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
256 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
257 Human cytomegalovirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
258 Human cytomegalovirus infection 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
259 Human immunodeficiency virus 1 infection 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
260 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
261 Human immunodeficiency virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
262 Human papillomavirus infection 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
263 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
264 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
265 Human T-cell leukemia virus 1 infection 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
266 Human T-cell leukemia virus 1 infection 💬
 [2] IL1R1, IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
267 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
268 Human T-cell leukemia virus 1 infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
269 Huntington disease 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
270 Hypertrophic cardiomyopathy 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
271 IL-17 signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
272 Inflammatory bowel disease 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
273 Inflammatory mediator regulation of TRP channels 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
274 Influenza A 💬
 [1] FDPS 💬 Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
275 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
276 Influenza A 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
277 Influenza A 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
278 Influenza A 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬
279 Insulin resistance 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
280 Insulin resistance 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
281 Insulin resistance 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
282 Insulin secretion 💬
 [2] ABCC8, KCNJ11 💬 Repaglinide 💬 Repaglinide [4]  6 , 21, 46, 299 💬
283 Insulin secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
284 Insulin secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
285 Insulin secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
286 Insulin secretion 💬
 [1] GLP1R 💬 Dulaglutide 💬 Dulaglutide [2] 13, 299 💬
287 Insulin signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
288 Insulin signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
289 Insulin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
290 Insulin signaling pathway 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
291 Insulin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
292 Intestinal immune network for IgA production 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
293 JAK-STAT signaling pathway 💬
 [1] CSF2RA 💬 Molgramostim 💬 Molgramostim [3] 97, 229, 299 💬
294 JAK-STAT signaling pathway 💬
 [1] GHR 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
295 JAK-STAT signaling pathway 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
296 JAK-STAT signaling pathway 💬
 [1] IL5RA 💬 Benralizumab 💬 Benralizumab [5] 44, 45, 98, 162, 299 💬
297 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] IFNGR1 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
298 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
299 Kaposi sarcoma-associated herpesvirus infection 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
300 Kaposi sarcoma-associated herpesvirus infection 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
301 Leishmaniasis 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
302 Leishmaniasis 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
303 Leukocyte transendothelial migration 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
304 Lipid and atherosclerosis 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
305 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
306 Lipid and atherosclerosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
307 Long-term depression 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
308 Long-term depression 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
309 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
310 Long-term potentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
311 Longevity regulating pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
312 Longevity regulating pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
313 Longevity regulating pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
314 Longevity regulating pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
315 Longevity regulating pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
316 Longevity regulating pathway - multiple species 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
317 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
318 Longevity regulating pathway - multiple species 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
319 Longevity regulating pathway - multiple species 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
320 Lysosome 💬
 [1] CTSC 💬 Brensocatib 💬 Brensocatib [1] 299 💬
321 MAPK signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
322 MAPK signaling pathway 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
323 MAPK signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
324 MAPK signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
325 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
326 MAPK signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
327 Melanoma 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
328 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
329 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
330 Metabolic pathways 💬
 [2] ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
331 Metabolic pathways 💬
 [1] FDPS 💬 Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
332 Metabolic pathways 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
333 Metabolic pathways 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
334 Metabolic pathways 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
335 Metabolic pathways 💬
 [1] HMGCR 💬 Atorvastatin 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
336 Metabolic pathways 💬
 [1] HMGCR 💬 Rosuvastatin 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
337 Metabolic pathways 💬
 [1] HMGCR 💬 Simvastatin 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
338 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
339 Metabolic pathways 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
340 Metabolic pathways 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
341 Metabolic pathways 💬
 [1] PDE5A 💬 Sildenafil 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
342 Metabolic pathways 💬
 [1] PDE5A 💬 Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬
343 Metabolic pathways 💬
 [2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
344 Metabolic pathways 💬
 [1] UGCG 💬 Miglustat 💬 Miglustat [3] 19, 256, 299 💬
345 MicroRNAs in cancer 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
346 Mineral absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
347 Mineral absorption 💬
 [1] CLCN2 💬 Lubiprostone 💬 Lubiprostone [4]  6 , 13, 290, 299 💬
348 Mineral absorption 💬
 [1] VDR 💬 Calcifediol 💬 Calcifediol [2] 113, 299 💬
349 Mineral absorption 💬
 [1] VDR 💬 Cholecalciferol 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
350 Mineral absorption 💬
 [1] VDR 💬 Ergocalciferol 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
351 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
352 Morphine addiction 💬
 [17] ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
353 Morphine addiction 💬
 [1] DRD1 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
354 Morphine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
355 Morphine addiction 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
356 mTOR signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
357 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
358 mTOR signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
359 mTOR signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
360 Natural killer cell mediated cytotoxicity 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
361 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
362 Natural killer cell mediated cytotoxicity 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
363 Necroptosis 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
364 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
365 Neuroactive ligand-receptor interaction 💬
 [2] ADORA1, ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
366 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
367 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
368 Neuroactive ligand-receptor interaction 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
369 Neuroactive ligand-receptor interaction 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
370 Neuroactive ligand-receptor interaction 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 Terlipressin 💬 Terlipressin [1] 299 💬
371 Neuroactive ligand-receptor interaction 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
372 Neuroactive ligand-receptor interaction 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
373 Neuroactive ligand-receptor interaction 💬
 [1] CNR2 💬 Lenabasum 💬 Ajulemic acid [3] 50, 51, 299 💬
374 Neuroactive ligand-receptor interaction 💬
 [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
375 Neuroactive ligand-receptor interaction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
376 Neuroactive ligand-receptor interaction 💬
 [1] GHR 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
377 Neuroactive ligand-receptor interaction 💬
 [1] GLP1R 💬 Dulaglutide 💬 Dulaglutide [2] 13, 299 💬
378 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Budesonide 💬 Budesonide [9] 66, 93, 94, 95, 96, 97, 98, 228, 299 💬
379 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Dexamethasone 💬 Dexamethasone [22] 13, 14, 16, 28, 35, 46, 53, 63, 64, 65, 70, 81, 84, 96, 97, 162, 222, 235, 257, 283, 296, 299 💬
380 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Fluticasone 💬 Fluticasone [3] 98, 228, 299 💬
381 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Hydrocortisone 💬 Hydrocortisone [10]  6 , 41, 46, 53, 75, 78, 81, 83, 97, 299 💬
382 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Prednisolone 💬 Prednisolone [42]  3 , 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 107, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬
383 Neuroactive ligand-receptor interaction 💬
 [1] NR3C1 💬 Prednisone 💬 Prednisone [45]  2 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 95, 96, 97, 113, 162, 164, 205, 222, 224, 228, 283, 284, 288, 299, 300, 307, 331 💬
384 Neuroactive ligand-receptor interaction 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬
385 Neuroactive ligand-receptor interaction 💬
 [1] PTGFR 💬 Tafluprost 💬 Tafluprost [1] 299 💬
386 NF-kappa B signaling pathway 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
387 NF-kappa B signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
388 NF-kappa B signaling pathway 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
389 Nicotine addiction 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
390 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
391 Non-alcoholic fatty liver disease 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
392 Non-alcoholic fatty liver disease 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
393 Non-alcoholic fatty liver disease 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
394 Non-small cell lung cancer 💬
 [1] RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬
395 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
396 Olfactory transduction 💬
 [4] PDE1A, PDE1B, PDE1C, PDE2A 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
397 Oocyte meiosis 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
398 Oocyte meiosis 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
399 Oocyte meiosis 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
400 Oocyte meiosis 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
401 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
402 Oocyte meiosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
403 Osteoclast differentiation 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
404 Osteoclast differentiation 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
405 Osteoclast differentiation 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
406 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
407 Osteoclast differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
408 Osteoclast differentiation 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
409 Ovarian steroidogenesis 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
410 Ovarian steroidogenesis 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
411 Ovarian steroidogenesis 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
412 Ovarian steroidogenesis 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
413 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 Esomeprazole 💬 Esomeprazole [8] 13, 46, 86, 98, 107, 113, 298, 299 💬
414 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 Lansoprazole 💬 Lansoprazole [7] 63, 71, 85, 98, 166, 222, 299 💬
415 Oxidative phosphorylation 💬
 [2] ATP4A, ATP4B 💬 Omeprazole 💬 Omeprazole [14]  6 ,  8 , 21, 46, 51, 85, 96, 97, 225, 271, 282, 294, 298, 299 💬
416 Oxytocin signaling pathway 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
417 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
418 Oxytocin signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
419 Oxytocin signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
420 Oxytocin signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
421 Pancreatic secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
422 Pancreatic secretion 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
423 Pancreatic secretion 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
424 Pancreatic secretion 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
425 Pancreatic secretion 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
426 Pancreatic secretion 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
427 Pancreatic secretion 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
428 Pancreatic secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
429 Pancreatic secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
430 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
431 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
432 Parathyroid hormone synthesis, secretion and action 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
433 Parathyroid hormone synthesis, secretion and action 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
434 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 Calcifediol 💬 Calcifediol [2] 113, 299 💬
435 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 Cholecalciferol 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
436 Parathyroid hormone synthesis, secretion and action 💬
 [1] VDR 💬 Ergocalciferol 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
437 Parkinson disease 💬
 [2] DRD1, DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
438 Pathogenic Escherichia coli infection 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
439 Pathways in cancer 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
440 Pathways in cancer 💬
 [1] CSF2RA 💬 Molgramostim 💬 Molgramostim [3] 97, 229, 299 💬
441 Pathways in cancer 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
442 Pathways in cancer 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
443 Pathways in cancer 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
444 Pathways in cancer 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
445 Pathways in cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
446 Pathways in cancer 💬
 [1] IL5RA 💬 Benralizumab 💬 Benralizumab [5] 44, 45, 98, 162, 299 💬
447 Pathways in cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
448 Pathways in cancer 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
449 Pathways in cancer 💬
 [2] RARA, RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬
450 Pathways of neurodegeneration - multiple diseases 💬
 [3] CHRM1, CHRM3, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
451 Pathways of neurodegeneration - multiple diseases 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
452 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
453 Pathways of neurodegeneration - multiple diseases 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
454 Pathways of neurodegeneration - multiple diseases 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
455 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
456 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
457 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
458 Phospholipase D signaling pathway 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
459 Phospholipase D signaling pathway 💬
 [3] AVPR1A, AVPR1B, AVPR2 💬 Terlipressin 💬 Terlipressin [1] 299 💬
460 Phospholipase D signaling pathway 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
461 Phospholipase D signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
462 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
463 Phospholipase D signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
464 Phospholipase D signaling pathway 💬
 [1] PTGFR 💬 Tafluprost 💬 Tafluprost [1] 299 💬
465 PI3K-Akt signaling pathway 💬
 [2] CHRM1, CHRM2 💬 Atropine 💬 Atropine [2]  2 , 299 💬
466 PI3K-Akt signaling pathway 💬
 [1] CHRM2 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
467 PI3K-Akt signaling pathway 💬
 [2] GHR, IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
468 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
469 PI3K-Akt signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
470 PI3K-Akt signaling pathway 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
471 Platelet activation 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
472 Platelet activation 💬
 [1] PTGS1 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
473 PPAR signaling pathway 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
474 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
475 Prion disease 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
476 Progesterone-mediated oocyte maturation 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
477 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
478 Progesterone-mediated oocyte maturation 💬
 [1] PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
479 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Norethindrone 💬 Norethisterone [4] 13, 46, 49, 299 💬
480 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Norgestimate 💬 Norgestimate [1] 299 💬
481 Progesterone-mediated oocyte maturation 💬
 [1] PGR 💬 Progesterone 💬 Progesterone [2] 76, 299 💬
482 Prolactin signaling pathway 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
483 Prolactin signaling pathway 💬
 [2] ESR1, ESR2 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
484 Prolactin signaling pathway 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
485 Prostate cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
486 Prostate cancer 💬
 [1] IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
487 Protein digestion and absorption 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
488 Protein digestion and absorption 💬
 [1] DPP4 💬 Saxagliptin 💬 Saxagliptin [1] 299 💬
489 Protein digestion and absorption 💬
 [1] DPP4 💬 Sitagliptin 💬 Sitagliptin [4]  6 , 75, 233, 299 💬
490 Proteoglycans in cancer 💬
 [1] ESR1 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
491 Proteoglycans in cancer 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
492 Proteoglycans in cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
493 Proximal tubule bicarbonate reclamation 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
494 Purine metabolism 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
495 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
496 Purine metabolism 💬
 [16] PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
497 Purine metabolism 💬
 [4] PDE4A, PDE4B, PDE4C, PDE4D 💬 Roflumilast 💬 Roflumilast [4] 84, 97, 206, 299 💬
498 Purine metabolism 💬
 [1] PDE5A 💬 Sildenafil 💬 Sildenafil [17]  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
499 Purine metabolism 💬
 [1] PDE5A 💬 Vardenafil 💬 Vardenafil [3] 13, 86, 299 💬
500 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
501 Rap1 signaling pathway 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
502 Rap1 signaling pathway 💬
 [1] DRD2 💬 Dopamine 💬 Dopamine [4]  6 ,  7 , 74, 299 💬
503 Rap1 signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
504 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
505 Rap1 signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
506 Ras signaling pathway 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
507 Ras signaling pathway 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
508 Ras signaling pathway 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
509 Regulation of actin cytoskeleton 💬
 [5] CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 💬 Atropine 💬 Atropine [2]  2 , 299 💬
510 Regulation of actin cytoskeleton 💬
 [2] CHRM2, CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
511 Regulation of actin cytoskeleton 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
512 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
513 Regulation of lipolysis in adipocytes 💬
 [2] ADORA1, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
514 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
515 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
516 Regulation of lipolysis in adipocytes 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
517 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
518 Regulation of lipolysis in adipocytes 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
519 Regulation of lipolysis in adipocytes 💬
 [2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
520 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
521 Renin secretion 💬
 [6] ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
522 Renin secretion 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
523 Renin secretion 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
524 Renin secretion 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
525 Renin secretion 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
526 Renin secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
527 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
528 Renin secretion 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
529 Renin-angiotensin system 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
530 Retrograde endocannabinoid signaling 💬
 [16] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
531 Retrograde endocannabinoid signaling 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
532 Rheumatoid arthritis 💬
 [1] TNFSF11 💬 Denosumab 💬 Denosumab [8] 46, 50, 70, 93, 95, 96, 274, 299 💬
533 Salivary secretion 💬
 [1] ADRB2 💬 Formoterol 💬 Formoterol [3] 85, 228, 299 💬
534 Salivary secretion 💬
 [1] ADRB2 💬 Albuterol 💬 Salbutamol [12]  3 , 11, 12, 13, 49, 85, 86, 89, 111, 113, 256, 299 💬
535 Salivary secretion 💬
 [1] ADRB2 💬 Salmeterol 💬 Salmeterol [1] 299 💬
536 Salivary secretion 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
537 Salivary secretion 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
538 Salivary secretion 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
539 Salivary secretion 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
540 Serotonergic synapse 💬
 [3] GABRB1, GABRB2, GABRB3 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
541 Serotonergic synapse 💬
 [2] PTGS1, PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
542 Serotonergic synapse 💬
 [1] SLC6A4 💬 Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
543 Shigellosis 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
544 Signaling pathways regulating pluripotency of stem cells 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
545 Small cell lung cancer 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
546 Small cell lung cancer 💬
 [1] RARB 💬 Fenretinide 💬 Fenretinide [1] 299 💬
547 Sphingolipid metabolism 💬
 [1] UGCG 💬 Miglustat 💬 Miglustat [3] 19, 256, 299 💬
548 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
549 Sphingolipid signaling pathway 💬
 [1] ADORA1 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
550 Sphingolipid signaling pathway 💬
 [1] FCER1A 💬 Omalizumab 💬 Omalizumab [7] 46, 53, 65, 98, 162, 226, 299 💬
551 Staphylococcus aureus infection 💬
 [1] PLG 💬 Tranexamic acid 💬 Tranexamic acid [7] 46, 70, 215, 227, 274, 288, 299 💬
552 Synaptic vesicle cycle 💬
 [2] SLC6A2, SLC6A4 💬 Amitriptyline 💬 Amitriptyline [4] 78, 97, 226, 299 💬
553 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
554 T cell receptor signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
555 Taste transduction 💬
 [1] CHRM3 💬 Atropine 💬 Atropine [2]  2 , 299 💬
556 Taste transduction 💬
 [1] CHRM3 💬 Pilocarpine 💬 Pilocarpine [3]  6 , 53, 299 💬
557 Taste transduction 💬
 [6] GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 💬 Midazolam 💬 Midazolam [12]  2 ,  3 ,  6 , 13, 21, 46, 70, 96, 97, 272, 298, 299 💬
558 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
559 Taste transduction 💬
 [3] PDE1A, PDE1B, PDE1C 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
560 Taste transduction 💬
 [3] SCNN1A, SCNN1B, SCNN1G 💬 Amiloride 💬 Amiloride [4] 13, 67, 225, 299 💬
561 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 Alendronic acid 💬 Alendronic acid [7] 19, 41, 46, 50, 271, 274, 299 💬
562 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
563 Terpenoid backbone biosynthesis 💬
 [1] FDPS 💬 Zoledronic acid 💬 Zoledronic acid [13]  5 ,  6 , 13, 17, 46, 65, 93, 95, 96, 270, 274, 299, 333 💬
564 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 Atorvastatin 💬 Atorvastatin [19] 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬
565 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 Rosuvastatin 💬 Rosuvastatin [11]  6 , 18, 46, 49, 51, 56, 79, 96, 97, 271, 299 💬
566 Terpenoid backbone biosynthesis 💬
 [1] HMGCR 💬 Simvastatin 💬 Simvastatin [21]  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
567 Th1 and Th2 cell differentiation 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
568 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
569 Th1 and Th2 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
570 Th17 cell differentiation 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
571 Th17 cell differentiation 💬
 [1] IL1R1 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
572 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
573 Th17 cell differentiation 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
574 Th17 cell differentiation 💬
 [1] RARA 💬 Fenretinide 💬 Fenretinide [1] 299 💬
575 Thermogenesis 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
576 Thermogenesis 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
577 Thyroid cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
578 Thyroid hormone signaling pathway 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
579 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 Estradiol 💬 Estradiol [7] 13, 46, 49, 65, 76, 226, 299 💬
580 Thyroid hormone signaling pathway 💬
 [1] ESR1 💬 Ethinyl estradiol 💬 Ethinylestradiol [4] 13, 46, 49, 299 💬
581 Thyroid hormone synthesis 💬
 [4] ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬 Digitoxin 💬 Digitoxin [1] 299 💬
582 Tight junction 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
583 Tight junction 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
584 Tight junction 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
585 Tight junction 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
586 Tight junction 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
587 Tight junction 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
588 Tight junction 💬
 [2] PRKAA1, PRKAA2 💬 Metformin 💬 Metformin [25]  2 ,  6 ,  8 , 13, 46, 49, 60, 65, 67, 75, 77, 81, 86, 97, 113, 127, 158, 206, 218, 225, 233, 265, 285, 299, 301 💬
589 TNF signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
590 Toxoplasmosis 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
591 Transcriptional misregulation in cancer 💬
 [1] IGF1R 💬 Mecasermin 💬 Mecasermin [6] 65, 78, 96, 168, 265, 299 💬
592 Transcriptional misregulation in cancer 💬
 [1] IL1R2 💬 Anakinra 💬 Anakinra [18]  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
593 Transcriptional misregulation in cancer 💬
 [1] PPARG 💬 Pioglitazone 💬 Pioglitazone [17]  2 ,  6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬
594 Transcriptional misregulation in cancer 💬
 [1] RARA 💬 Fenretinide 💬 Fenretinide [1] 299 💬
595 Tuberculosis 💬
 [2] IFNGR1, IFNGR2 💬 Interferon gamma-1b 💬 Interferon gamma-1b [7] 18, 65, 85, 228, 299, 301, 326 💬
596 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
597 Tuberculosis 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
598 Tuberculosis 💬
 [1] VDR 💬 Calcifediol 💬 Calcifediol [2] 113, 299 💬
599 Tuberculosis 💬
 [1] VDR 💬 Cholecalciferol 💬 Cholecalciferol [24]  6 , 13, 19, 20, 28, 34, 46, 49, 51, 53, 56, 60, 65, 84, 85, 96, 97, 98, 162, 202, 228, 271, 298, 299 💬
600 Tuberculosis 💬
 [1] VDR 💬 Ergocalciferol 💬 Ergocalciferol [6] 46, 49, 84, 96, 97, 299 💬
601 Type II diabetes mellitus 💬
 [2] ABCC8, KCNJ11 💬 Repaglinide 💬 Repaglinide [4]  6 , 21, 46, 299 💬
602 Type II diabetes mellitus 💬
 [1] INSR 💬 Insulin detemir 💬 Insulin detemir [1] 299 💬
603 Type II diabetes mellitus 💬
 [1] INSR 💬 Insulin glargine 💬 Insulin glargine [1] 299 💬
604 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
605 Vascular smooth muscle contraction 💬
 [1] ADORA2B 💬 Theophylline 💬 Theophylline [2] 236, 299 💬
606 Vascular smooth muscle contraction 💬
 [1] AGTR1 💬 Losartan 💬 Losartan [17] 17, 19, 36, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
607 Vascular smooth muscle contraction 💬
 [2] AVPR1A, AVPR1B 💬 Terlipressin 💬 Terlipressin [1] 299 💬
608 Vascular smooth muscle contraction 💬
 [3] GUCY1A1, GUCY1A2, GUCY1B1 💬 Riociguat 💬 Riociguat [6] 51, 84, 86, 88, 225, 299 💬
609 Vasopressin-regulated water reabsorption 💬
 [1] AVPR2 💬 Terlipressin 💬 Terlipressin [1] 299 💬
610 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
611 VEGF signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
612 VEGF signaling pathway 💬
 [1] PTGS2 💬 Ibuprofen 💬 Ibuprofen [7] 13, 46, 65, 107, 113, 271, 299 💬
613 Vibrio cholerae infection 💬
 [1] CFTR 💬 Deutivacaftor 💬 Deutivacaftor [1] 299 💬
614 Vibrio cholerae infection 💬
 [1] CFTR 💬 Elexacaftor 💬 Elexacaftor [1] 299 💬
615 Vibrio cholerae infection 💬
 [1] CFTR 💬 Galicaftor 💬 Galicaftor [1] 299 💬
616 Vibrio cholerae infection 💬
 [1] CFTR 💬 Ivacaftor 💬 Ivacaftor [1] 299 💬
617 Vibrio cholerae infection 💬
 [1] CFTR 💬 Lumacaftor 💬 Lumacaftor [1] 299 💬
618 Vibrio cholerae infection 💬
 [1] CFTR 💬 Tezacaftor 💬 Tezacaftor [1] 299 💬
619 Viral life cycle - HIV-1 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
620 Viral protein interaction with cytokine and cytokine receptor 💬
 [2] CXCR1, CXCR2 💬 Reparixin 💬 Reparixin [2] 298, 299 💬
621 Viral protein interaction with cytokine and cytokine receptor 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
622 Virion - Human immunodeficiency virus 💬
 [1] CXCR4 💬 Plerixafor 💬 Plerixafor [5] 19, 20, 65, 285, 299 💬
623 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬
624 Wnt signaling pathway 💬
 [5] PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 Tacrolimus 💬 Tacrolimus [34]  2 ,  6 , 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299 💬

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