Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Glutamine
(Synonym: Endari (TN))		[1] L-Glutamine (Synonym: Endari)[2] Glutamine; L-Glutamine; --[7] 87, 89, 96, 97, 113, 245, 299
2 Progesterone
(Synonym: ENDOMETRIN)		[1] Progesterone (Synonym: Endometrin)[1] Progesterone; [1] PGR 💬[5] Breast cancer, Chemical carcinogenesis - receptor activation, Estrogen signaling pathway, Oocyte meiosis, Progesterone-mediated oocyte maturation 💬[1] 76
3 Tacrolimus
(Synonym: ENVARSUS)		[1] Tacrolimus (Synonym: Envarsus)[2] Prograf; TACROLIMUS; [5] PPP3CA,
PPP3CB,
PPP3CC,
PPP3R1,
PPP3R2 💬		[33] Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬[34] 2, 6, 11, 13, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 85, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 283, 284, 285, 286, 299
4 Glycyrrhetinic acid
(Synonym: Enoxolone (INN))		-[0] ---
5 Budesonide
(Synonym: Entocort EC (TN))		[1] Budesonide (Synonym: Entocort Enema)[4] BUDESONIDE; Entocort; Jorveza; Symbicort; [1] NR3C1 💬[1] Neuroactive ligand-receptor interaction 💬[9] 66, 93, 94, 95, 96, 97, 98, 228, 299
6 Enoxacin [1] Enoxacin[1] Enoxacin; --[1] 2
7 Triacetin
(Synonym: Enzactin (TN))		[1] Triacetin[1] Glyceryl triacetate; --[1] 307
8 Enflurane -[0] ---
9 Enalapril maleate [1] Enalapril[2] Enalapril; Enalapril Maleate; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
10 Methyclothiazide
(Synonym: Enduron (TN))		-[0] ---
11 Etanercept
(Synonym: Enbrel (TN))		[1] Etanercept (Synonym: Enbrel)[4] Benepali; ENBREL; Erelzi; Etanercept; [2] LTA,
TNF 💬		[67] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antifolate resistance, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬[17] 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298
12 Entacapone [1] Entacapone[5] COMTAN; Comtess; ENTACAPONA; Entacapone; Stalevo; [1] COMT 💬[4] Dopaminergic synapse, Metabolic pathways, Steroid hormone biosynthesis, Tyrosine metabolism 💬[2] 6, 17
13 Fluphenazine enanthate -[0] ---
14 Testosterone enanthate [2] Testosterone,
Testosterone enanthate		[3] Testosterone; Testosterone Enanthate; Xyosted; [1] AR 💬[4] Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬[11] 1, 2, 3, 13, 13, 60, 76, 78, 113, 113, 265
15 Edrophonium chloride
(Synonym: Enlon (TN))		-[0] ---
16 Iodoxamic acid
(Synonym: Endobil (TN))		-[0] ---
17 Clothiapine
(Synonym: Entumin (TN))		-[0] ---
18 Darifenacin hydrobromide
(Synonym: Enablex (TN))		[1] Darifenacin (Synonym: Enablex)[2] Darifenacin; Emselex; [1] CHRM3 💬[11] Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬[2] 6, 13
19 Edetate disodium
(Synonym: Endrate (TN))		[1] Edetic acid[1] EDTA; --[2] 51, 60
20 Enprostil -[0] ---
21 Barium sulfate
(Synonym: ENTERO VU 24%)		-[0] ---
22 Ferrous gluconate
(Synonym: Enterued (TN))		-[0] ---
23 Enrofloxacin -[0] ---
24 Enfuvirtide [1] Enfuvirtide[1] Enfuvirtide; --[2] 25, 265
25 Alvimopan
(Synonym: Entereg (TN))		-[0] ---
26 Enoxaparin sodium [1] Enoxaparin[1] Enoxaparin; [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[1] 46
27 Enalkiren -[0] ---
28 Enalaprilat -[0] ---
29 Dienogest
(Synonym: Endometrion (TN))		-[0] ---
30 Disodium edetate
(Synonym: Endrate (TN))		[1] Edetic acid[1] EDTA; --[2] 51, 60
31 Encainide hydrochloride -[0] ---
32 Eniluracil -[0] ---
33 Enoximone -[0] ---
34 Enprofylline -[0] ---
35 Entecavir [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271
36 Enzacamene -[0] ---
37 Estradiol enanthate [1] Estradiol[1] Estradiol; [2] ESR1,
ESR2 💬		[10] Breast cancer, Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Endocrine resistance, Estrogen signaling pathway, GnRH secretion, Pathways in cancer, Prolactin signaling pathway, Proteoglycans in cancer, Thyroid hormone signaling pathway 💬[7] 13, 46, 49, 65, 76, 226, 299
38 Enoxacin hydrate [1] Enoxacin[1] Enoxacin; --[1] 2
39 Synthetic conjugated estrogens, B
(Synonym: Enjuvia (TN))		[1] Conjugated estrogens[1] Conjugated equine estrogens; --[1] 49
40 Adomiparin
(Synonym: Enoxaparin)		[3] Enoxaparin,
Heparin,
Parnaparin		[5] Enoxaparin; Heparin; Heparin Sodium; Parnaparin; PARNAPARIN SODIUM; [1] SERPINC1 💬[1] Complement and coagulation cascades 💬[14] 46, 47, 60, 70, 79, 84, 97, 107, 224, 226, 280, 299, 316, 317
41 Enalapril [1] Enalapril[2] Enalapril; Enalapril Maleate; [1] ACE 💬[6] Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬[6] 19, 46, 66, 113, 210, 222
42 Enbucrilate -[0] ---
43 Encainide -[0] ---
44 Entecavir [1] Entecavir[1] Entecavir; --[6] 46, 56, 96, 97, 107, 271
45 Enviomycin -[0] ---
46 Vedolizumab
(Synonym: Entyvio (TN))		[1] Vedolizumab (Synonym: Entyvio)[2] ENTYVIO; VEDOLIZUMAB; [2] ITGA4,
ITGB7 💬		[15] Arrhythmogenic right ventricular cardiomyopathy, Cell adhesion molecules, Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Human papillomavirus infection, Hypertrophic cardiomyopathy, Intestinal immune network for IgA production, Leishmaniasis, Leukocyte transendothelial migration, PI3K-Akt signaling pathway, Regulation of actin cytoskeleton, Transcriptional misregulation in cancer, Yersinia infection 💬[3] 94, 96, 97
47 Endralazine -[0] ---
48 Perphenazine enantate -[0] ---
49 Enclomiphene -[0] ---
50 Saruplase
(Synonym: Prourokinase (enzyme activating) (human clone pUK4/pUK18), nonglycosylated)		-[0] ---
51 Entinostat -[0] ---
52 Gabapentin enacarbil -[0] ---
53 Enokizumab -[0] ---
54 Ensituximab -[0] ---
55 Ensulizole -[0] ---
56 Enzalutamide -[0] ---
57 Enobosarm -[0] ---
58 Entolimod -[0] ---
59 Encenicline -[0] ---
60 Enasidenib -[0] ---
61 Entrectinib -[0] ---
62 Encorafenib -[0] ---
63 Satralizumab
(Synonym: Enspryng (TN))		[1] Satralizumab (Synonym: Enspryng)[2] Enspryng; SATRALIZUMAB; [1] IL6R 💬[12] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathways in cancer, Th17 cell differentiation, Viral protein interaction with cytokine and cytokine receptor 💬[2] 11, 13
64 Entospletinib -[0] ---
65 Ensartinib -[0] ---
66 Enarodustat -[0] ---
67 Enfortumab vedotin -[0] ---
68 Trastuzumab deruxtecan
(Synonym: Enhertu (TN))		-[0] ---
69 Ensifentrine -[0] ---
70 Enoblituzumab -[0] ---
71 Enzastaurin -[0] ---