Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank Drug (Description in trials) KEGG GENES KEGG PATHWAY Disease ID
1 Calcitriol
(Synonym: Rocaltrol (TN))		[1] Calcitriol (Synonym: Rocaltrol)[1] Calcitriol; [1] VDR 💬[5] Chemical carcinogenesis - receptor activation, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption, Parathyroid hormone synthesis, secretion and action, Tuberculosis 💬[9] 18, 37, 46, 49, 66, 96, 158, 235, 326
2 Guaifenesin
(Synonym: Robitussin (TN))		-[0] ---
3 Mesalamine
(Synonym: Rowasa (TN))		[1] Mesalazine (Synonym: sF Rowasa)[10] 5-AminoSalicylic Acid; 5-ASA; ASACOL; Mesalamine; MESALAZINA; MESALAZINE; Mesalazinum; MEZAVANT; Pentasa; Salofalk; --[4] 46, 96, 97, 164
4 Methocarbamol
(Synonym: Robaxin (TN))		-[0] ---
5 Metronidazole
(Synonym: ROSADAN)		[1] Metronidazole (Synonym: Rosadan)[3] Flagyl; Metronidazol; METRONIDAZOLE; --[8] 46, 51, 63, 94, 95, 96, 97, 291
6 Minoxidil
(Synonym: Rogaine (TN))		[1] Minoxidil (Synonym: Club Roots - Topical Solution Hair Regrowth Treatment)[1] MINOXIDIL; [2] ABCC8,
KCNJ11 💬		[4] ABC transporters, GnRH secretion, Insulin secretion, Type II diabetes mellitus 💬[1] 179
7 Glycopyrrolate
(Synonym: Robinul (TN))		-[0] ---
8 Rofecoxib [1] Rofecoxib[1] Rofecoxib; [1] PTGS2 💬[22] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[1] 46
9 Rosiglitazone maleate [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
10 Flumazenil
(Synonym: Romazicon (TN))		[1] Flumazenil (Synonym: Romazicon)[1] Flumazenil; [16] GABRA1,
GABRA2,
GABRA3,
GABRA4,
GABRA5,
GABRA6,
GABRB1,
GABRB2,
GABRB3,
GABRD,
GABRE,
GABRG1,
GABRG2,
GABRG3,
GABRP,
GABRQ 💬		[7] GABAergic synapse, Morphine addiction, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬[5] 6, 13, 17, 18, 206
11 Interferon alfa-2a
(Synonym: Roferon A (TN))		[1] Interferon alfa-2a (Synonym: Roferon A Sterile Pws 9m Unit/vial)[3] Interferon Alfa-2A; Interferon alpha-2a; Roferon-A; [2] IFNAR1,
IFNAR2 💬		[18] Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬[1] 56
12 Rocuronium bromide [1] Rocuronium[1] Rocuronium; [16] CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5,
CHRNA10,
CHRNA2,
CHRNA3,
CHRNA4,
CHRNA5,
CHRNA6,
CHRNA7,
CHRNA9,
CHRNB2,
CHRNB3,
CHRNB4 💬		[15] Alzheimer disease, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand-receptor interaction, Nicotine addiction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬[1] 296
13 Ropinirole hydrochloride [1] Ropinirole[3] REQUIP; ROPINIROLE; Ropinirole Hydrochloride; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
14 Ceftriaxone sodium
(Synonym: Rocephin (TN))		[1] Ceftriaxone (Synonym: Rocephin Pws 2gm/vial)[1] Ceftriaxone; --[3] 2, 6, 97
15 Trapidil
(Synonym: Rocornal (TN))		-[0] ---
16 Flunitrazepam
(Synonym: Rohypnol (TN))		-[0] ---
17 Flurbiprofen axetil
(Synonym: Ropion (TN))		[1] Flurbiprofen[1] Flurbiprofen; [2] PTGS1,
PTGS2 💬		[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬[3] 13, 21, 46
18 Roxithromycin [1] Roxithromycin[1] Roxithromycin; --[2] 46, 299
19 Rolipram [1] Rolipram[1] Rolipram; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 8, 13
20 Rokitamycin -[0] ---
21 Rosuvastatin calcium [1] Rosuvastatin[3] Crestor; Rosuvastatin; Rosuvastatin calcium; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
22 Rolitetracycline -[0] ---
23 Rosoxacin -[0] ---
24 Benznidazole
(Synonym: Rochagan (TN))		[1] Benznidazole[1] Benznidazole; --[1] 65
25 Ramelteon
(Synonym: Rozerem (TN))		[1] Ramelteon (Synonym: Rozerem)[2] Ramelteon; ROZEREM; [2] MTNR1A,
MTNR1B 💬		[2] Circadian entrainment, Neuroactive ligand-receptor interaction 💬[3] 6, 8, 46
26 Dihydroxyaluminum sodium carbonate
(Synonym: Rolaids (TN))		-[0] ---
27 Ropivacaine hydrochloride [1] Ropivacaine[1] Ropivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 36, 46, 70
28 Nicotinyl alcohol
(Synonym: Roniacol (TN))		-[0] ---
29 Roflumilast [1] Roflumilast[1] Roflumilast; [4] PDE4A,
PDE4B,
PDE4C,
PDE4D 💬		[5] Metabolic pathways, Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬[2] 84, 299
30 Ronnel -[0] ---
31 Roquinimex -[0] ---
32 Rostaporfin -[0] ---
33 Rotigaptide -[0] ---
34 Rotigotine [1] Rotigotine[3] NEUPRO; ROTIGOTINA; ROTIGOTINE; [1] DRD2 💬[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[2] 6, 127
35 Roxarsone -[0] ---
36 Spiramycin
(Synonym: Rovamycin (TN))		-[0] ---
37 Romidepsin -[0] ---
38 Angelica dahurica root -[0] ---
39 Rosin -[0] ---
40 Rociverine -[0] ---
41 Ronifibrate -[0] ---
42 Robenidine -[0] ---
43 Romifidine -[0] ---
44 Ropinirole [1] Ropinirole[3] Requip; Ropinirole; ROPINIROLE HYDROCHLORIDE; [3] DRD2,
DRD3,
DRD4 💬		[8] Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬[4] 2, 6, 74, 309
45 Ropivacaine [1] Ropivacaine[1] Ropivacaine; [5] SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬		[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬[3] 36, 46, 70
46 Rosiglitazone [1] Rosiglitazone[2] Rosiglitazone; Rosiglitazone maleate; [1] PPARG 💬[11] AMPK signaling pathway, Huntington disease, Lipid and atherosclerosis, Longevity regulating pathway, Non-alcoholic fatty liver disease, Osteoclast differentiation, PPAR signaling pathway, Pathways in cancer, Thermogenesis, Thyroid cancer, Transcriptional misregulation in cancer 💬[5] 46, 75, 97, 222, 265
47 Rosuvastatin [1] Rosuvastatin[3] Crestor; Rosuvastatin; ROSUVASTATIN CALCIUM; [1] HMGCR 💬[4] AMPK signaling pathway, Bile secretion, Metabolic pathways, Terpenoid backbone biosynthesis 💬[11] 6, 18, 46, 49, 51, 56, 79, 96, 97, 271, 299
48 Roxatidine acetate -[0] ---
49 Rolofylline -[0] ---
50 Romiplostim [1] Romiplostim[2] NPLATE; ROMIPLOSTIM; [1] MPL 💬[2] Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway 💬[4] 60, 63, 64, 65
51 Ropidoxuridine -[0] ---
52 Salvia miltiorrhiza root -[0] ---
53 Rontalizumab [1] Rontalizumab[1] Rontalizumab; [13] IFNA1,
IFNA10,
IFNA13,
IFNA14,
IFNA16,
IFNA17,
IFNA2,
IFNA21,
IFNA4,
IFNA5,
IFNA6,
IFNA7,
IFNA8 💬		[25] Alcoholic liver disease, Autoimmune thyroid disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, PI3K-Akt signaling pathway, Pathways in cancer, RIG-I-like receptor signaling pathway, Toll-like receptor signaling pathway, Tuberculosis 💬[1] 49
54 Rozrolimupab -[0] ---
55 Royal jelly [1] Royal jelly[1] Royal jelly; --[1] 49
56 Robatumumab -[0] ---
57 Romosozumab [1] Romosozumab[2] Evenity; ROMOSOZUMAB; [1] SOST 💬[2] Parathyroid hormone synthesis, secretion and action, Wnt signaling pathway 💬[1] 274
58 Roxadustat -[0] ---
59 Rolapitant -[0] ---
60 Panax notoginseng root -[0] ---
61 Rociletinib -[0] ---
62 Entrectinib
(Synonym: Rozlytrek (TN))		-[0] ---
63 Rovalpituzumab tesirine -[0] ---
64 Ropeginterferon alfa-2b -[0] ---
65 Roluperidone -[0] ---
66 Rovazolac -[0] ---
67 Romilkimab -[0] ---
68 Rovafovir etalafenamide -[0] ---
69 Marsh mallow
(Synonym: Althea root)		-[0] ---
70 Rozanolixizumab [1] Rozanolixizumab[1] ROZANOLIXIZUMAB; [1] FCGRT 💬-[3] 11, 14, 63