Target Gene/Pathway Pathway / Gene

  

Search results

No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank Disease ID
1 ESR1 [1] Thyroid hormone signaling pathway D00105 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
2 ESR1 [1] Thyroid hormone signaling pathway D00185 Estriol [2] 13, 227
3 ESR1 [1] Thyroid hormone signaling pathway D00289 Danazol [5] 60, 63, 64, 65, 285
4 ESR1 [1] Thyroid hormone signaling pathway D00554 Ethinylestradiol [4] 13, 46, 49, 299
5 ESR1 [1] Thyroid hormone signaling pathway D00575 Mestranol [2] 46, 49
6 ESR1 [1] Thyroid hormone signaling pathway D00962 Clomifene [1] 74
7 ESR1 [1] Thyroid hormone signaling pathway D00966 Tamoxifen [4] 2, 86, 113, 227
8 ESR1 [1] Thyroid hormone signaling pathway D01161 Fulvestrant [2] 49, 86
9 ESR1 [1] Thyroid hormone signaling pathway D01413 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
10 ESR1 [1] Thyroid hormone signaling pathway D01413 Estradiol valerate [1] 65
11 ESR1 [1] Thyroid hormone signaling pathway D01617 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
12 ESR1 [1] Thyroid hormone signaling pathway D01953 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
13 ESR1 [1] Thyroid hormone signaling pathway D01986 Estriol [2] 13, 227
14 ESR1 [1] Thyroid hormone signaling pathway D02217 Raloxifene [1] 46
15 ESR1 [1] Thyroid hormone signaling pathway D02367 Desogestrel [1] 230
16 ESR1 [1] Thyroid hormone signaling pathway D04061 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
17 ESR1 [1] Thyroid hormone signaling pathway D04063 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
18 ESR1 [1] Thyroid hormone signaling pathway D04064 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
19 ESR1 [1] Thyroid hormone signaling pathway D04065 Estradiol [7] 13, 46, 49, 65, 76, 226, 299
20 ESR1 [1] Thyroid hormone signaling pathway D07726 Clomifene [1] 74
21 ESR1 [1] Thyroid hormone signaling pathway D08409 Prasterone [6] 49, 53, 83, 86, 96, 113
22 ESR1 [1] Thyroid hormone signaling pathway D08465 Raloxifene [1] 46
23 ESR1 [1] Thyroid hormone signaling pathway D08559 Tamoxifen [4] 2, 86, 113, 227
24 ESR1 [1] Thyroid hormone signaling pathway D11513 Estetrol [1] 53
25 ESR1 [1] Thyroid hormone signaling pathway D11514 Estetrol [1] 53
26 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D00753 Sirolimus [41] 2, 6, 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 193, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331
27 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D02714 Everolimus [9] 34, 67, 89, 96, 137, 157, 158, 228, 277
28 MTOR [2] Thyroid hormone signaling pathway, Type II diabetes mellitus D06068 Temsirolimus [4] 13, 34, 89, 331
29 HDAC1 [3] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [3] 19, 75, 96
30 HDAC2 [3] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer, Viral carcinogenesis D06320 Vorinostat [3] 19, 75, 96
31 MYH7 [2] Thyroid hormone signaling pathway, Viral myocarditis D12265 Mavacamten [1] 58
32 ATP1A1 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
33 ATP1A1 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
34 ATP1A2 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
35 ATP1A2 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
36 ATP1A3 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
37 ATP1A3 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
38 ATP1A4 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00297 Digitoxin [1] 299
39 ATP1A4 [2] Thyroid hormone synthesis, Thyroid hormone signaling pathway D00298 Digoxin [3] 8, 46, 210
40 PIK3CA [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
41 PIK3CB [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
42 PIK3CD [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11158 Leniolisib [2] 53, 65
43 PIK3CD [7] VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Type II diabetes mellitus, Yersinia infection, Viral carcinogenesis D11437 Parsaclisib [3] 35, 53, 61
44 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
45 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
46 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
47 MAP2K1 [6] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, TNF signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
48 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D09666 Selumetinib [1] 34
49 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10175 Trametinib [4] 2, 34, 279, 280
50 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10405 Cobimetinib [1] 280
51 MAP2K2 [5] Vascular smooth muscle contraction, VEGF signaling pathway, Toll-like receptor signaling pathway, Thyroid hormone signaling pathway, Yersinia infection D10604 Binimetinib [1] 34
52 RAF1 [4] Vascular smooth muscle contraction, VEGF signaling pathway, Thyroid hormone signaling pathway, Tuberculosis D06272 Sorafenib [2] 34, 86
53 RAF1 [4] Vascular smooth muscle contraction, VEGF signaling pathway, Thyroid hormone signaling pathway, Tuberculosis D08524 Sorafenib [2] 34, 86
54 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
55 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
56 RXRA [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
57 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
58 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
59 RXRB [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
60 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02754 Acitretin [1] 37
61 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D02815 Alitretinoin [1] 49
62 RXRG [2] Thyroid hormone signaling pathway, Transcriptional misregulation in cancer D03106 Bexarotene [2] 13, 75
63 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03252 Bosutinib [2] 2, 67
64 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D03658 Dasatinib [2] 51, 85
65 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D06414 Dasatinib [2] 51, 85
66 SRC [6] VEGF signaling pathway, Tight junction, Thyroid hormone signaling pathway, Yersinia infection, Tuberculosis, Viral carcinogenesis D09664 Saracatinib [3] 6, 89, 272
67 THRA [1] Thyroid hormone signaling pathway D01010 Levothyroxine [5] 19, 49, 78, 80, 222
68 THRA [1] Thyroid hormone signaling pathway D01011 Liothyronine [4] 13, 78, 210, 212
69 THRA [1] Thyroid hormone signaling pathway D07214 Tiratricol [2] 78, 139
70 THRA [1] Thyroid hormone signaling pathway D08125 Levothyroxine [5] 19, 49, 78, 80, 222
71 THRA [1] Thyroid hormone signaling pathway D08128 Liothyronine [4] 13, 78, 210, 212
72 THRB [1] Thyroid hormone signaling pathway D01010 Levothyroxine [5] 19, 49, 78, 80, 222
73 THRB [1] Thyroid hormone signaling pathway D01011 Liothyronine [4] 13, 78, 210, 212
74 THRB [1] Thyroid hormone signaling pathway D07214 Tiratricol [2] 78, 139
75 THRB [1] Thyroid hormone signaling pathway D08125 Levothyroxine [5] 19, 49, 78, 80, 222
76 THRB [1] Thyroid hormone signaling pathway D08128 Liothyronine [4] 13, 78, 210, 212
77 THRB [1] Thyroid hormone signaling pathway D09381 Sobetirome [1] 20
78 CASP9 [5] VEGF signaling pathway, Thyroid hormone signaling pathway, Toxoplasmosis, Tuberculosis, Viral myocarditis D11195 Rimiducid [6] 19, 60, 65, 284, 285, 326
79 HDAC3 [2] Thyroid hormone signaling pathway, Viral carcinogenesis D06320 Vorinostat [3] 19, 75, 96