Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
113c6 leucine----3件: 5, 7, 127 💬
218F-AV-1451----3件: 5, 7, 127 💬
318F-AV-45----2件: 6, 127 💬
418F-FDG1件: Fludeoxyglucose (18F)1件: Fludeoxyglucose F 18 💬 --8件: 5, 6, 7, 46, 84, 85, 127, 300 💬
518F-RO6958948----3件: 5, 7, 127 💬
63 tesla MRI----1件: 127 💬
7Adeno-associated viral vector serotype 9 expressing codon-optimized human GRN gene----1件: 127 💬
8AL-108----3件: 5, 7, 127 💬
9AL0011件: Latozinemab1件: Latozinemab 💬 1件: SORT1 💬 3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬2件: 2, 127 💬
10Amantadine1件: Amantadine2件: Amantadine hydrochloride ,
Amantadine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬4件: 6, 8, 13, 127 💬
11Amiodarone1件: Amiodarone2件: Amiodarone hydrochloride ,
Amiodarone 💬 		16件: ADRA1A,
ADRA1B,
ADRA1D,
ADRB1,
KCND3,
KCNJ11,
KCNJ12_18,
KCNJ3,
KCNJ5,
KCNJ8,
KCNQ1,
SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		34件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Dilated cardiomyopathy, Dopaminergic synapse, Estrogen signaling pathway, Gap junction, Gastric acid secretion, Glutamatergic synapse, GnRH secretion, Hormone signaling, Insulin secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, Pancreatic secretion, Protein digestion and absorption, Regulation of lipolysis in adipocytes, Renin secretion, Retrograde endocannabinoid signaling, Salivary secretion, Serotonergic synapse, Spinocerebellar ataxia, Taste transduction, Type II diabetes mellitus, Vascular smooth muscle contraction, Vibrio cholerae infection, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 127 💬
12Amyvid----1件: 127 💬
13Apolipoprotein E genetic test----1件: 127 💬
14AV1451 TAU----3件: 6, 17, 127 💬
15AVB-1011件: AVB-101---1件: 127 💬
16BIIB092----3件: 5, 7, 127 💬
17Blood sample----28件: 2, 3, 8, 13, 34, 46, 49, 51, 53, 61, 65, 66, 67, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 280, 288, 294, 299 💬
18Brain PET scan----3件: 5, 7, 127 💬
19C-11 ER176----3件: 6, 17, 127 💬
20C-11 PIB1件: Pittsburgh Compound B---3件: 6, 17, 127 💬
21Censavudine1件: Censavudine1件: Censavudine 💬 --3件: 2, 127, 325 💬
22Citalopram1件: Citalopram2件: Citalopram hydrobromide ,
Citalopram 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬5件: 6, 13, 46, 98, 127 💬
23Cognitive and behavioral experimental tasks----1件: 127 💬
24Davunetide1件: Davunetide1件: Davunetide 💬 --3件: 5, 7, 127 💬
25DNL593----1件: 127 💬
26DNL593 sterile lyophilisate----1件: 127 💬
27Donepezil1件: Donepezil2件: Donepezil hydrochloride ,
Donepezil 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
28DPA----4件: 2, 6, 13, 127 💬
29Ecocapture----1件: 127 💬
30Elecsys (roche) abeta42, ttau and ptau----5件: 5, 6, 7, 17, 127 💬
31Electroencephalogram----2件: 6, 127 💬
32ET-stem----1件: 127 💬
33EVP-0334----1件: 127 💬
34F 18 T807----2件: 2, 127 💬
35F-18----3件: 5, 7, 127 💬
36F-18 AV 1451----2件: 5, 127 💬
37F-18 FDG----1件: 127 💬
38Ferulic acid1件: Ferulic acid---1件: 127 💬
39Florbetapir 18F----1件: 127 💬
40Florbetapir 18F injection----1件: 127 💬
41Flortaucipir F181件: Flortaucipir1件: Flortaucipir F 18 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬3件: 5, 7, 127 💬
42Flutemetamol1件: Flutemetamol---4件: 5, 6, 7, 127 💬
43Flutemetamol F18 injection2件: Flutemetamol,
Flutemetamol (18F)		1件: Flutemetamol F 18 💬 --5件: 5, 6, 7, 17, 127 💬
44FPI-2620----1件: 127 💬
45FRM-0334----1件: 127 💬
46Galantamine hydrobromide1件: Galantamine2件: Galantamine hydrobromide ,
Galantamine 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬2件: 6, 127 💬
47Histone deacetylase inhibitor----1件: 127 💬
48Icm_apathy_tasks----1件: 127 💬
49Injection----6件: 2, 5, 6, 7, 17, 127 💬
50Intranasal oxytocin----2件: 127, 193 💬
51Intrathalamic AAV.pgrn administration----1件: 127 💬
52Intrathalamic AVB-101----1件: 127 💬
53Ketogenic diet----9件: 13, 19, 21, 49, 67, 77, 127, 145, 148 💬
54Latozinemab1件: Latozinemab1件: Latozinemab 💬 1件: SORT1 💬 3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127 💬
55Lemborexant 5 MG1件: Lemborexant1件: Lemborexant 💬 2件: HCRTR1,
HCRTR2 💬 		2件: Hormone signaling, Neuroactive ligand-receptor interaction 💬1件: 127 💬
56Lithium carbonate2件: Lithium carbonate,
Lithium citrate		2件: Lithium carbonate ,
Lithium citrate 💬 		--5件: 2, 13, 17, 18, 127 💬
57Lmtm1件: Hydromethylthionine mesylate1件: Hydromethylthionine mesylate 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127 💬
58Lmtm/TRX02371件: Hydromethylthionine mesylate1件: Hydromethylthionine mesylate 💬 1件: MAPT 💬 4件: Alzheimer disease, MAPK signaling pathway, Parkinson disease, Pathways of neurodegeneration - multiple diseases 💬1件: 127 💬
59Lumbar puncture----6件: 6, 13, 19, 96, 97, 127 💬
60Lumipulse (fujirebio) abeta42, ttau and ptau----5件: 5, 6, 7, 17, 127 💬
61LY3884963----1件: 127 💬
62Memantine1件: Memantine2件: Memantine hydrochloride ,
Memantine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
63Memantine hydrochloride1件: Memantine2件: Memantine hydrochloride ,
Memantine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬3件: 2, 6, 127 💬
64Metformin1件: Metformin2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬23件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 84, 86, 97, 113, 127, 206, 218, 225, 265, 285, 298 💬
65Methylprednisolone1件: Methylprednisolone2件: Methylprednisolone ,
Methylprednisolone acetate 💬 		1件: NR3C1 💬 1件: Neuroactive ligand-receptor interaction 💬45件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 96, 97, 127, 162, 164, 222, 224, 271, 283, 284, 285, 296, 300 💬
66Methylthioninium1件: Methylthioninium---1件: 127 💬
67Methylthioninium chloride2件: Methylene blue,
Methylthioninium		2件: Methylene blue ,
Methylthioninium chloride hydrate 💬 		--1件: 127 💬
68MTC TRX0014-001 capsules----1件: 127 💬
69Nabilone1件: Nabilone1件: Nabilone 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬4件: 6, 13, 97, 127 💬
70Neupro - 2 MG/24 H + 4 MG/24 H + 6 MG/24 H+ 8 MG/24 H cerotto otto transdermico 7 cerotti + 7 cerotti + 7 cerotti + 7 cerotti trandermici IN bustina1件: Rotigotine1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 127 💬
71Neurohormonal mechanisms----1件: 127 💬
72Neuropsychological assessment----1件: 127 💬
73Novolin-R insulin----1件: 127 💬
74Open label - AL0011件: Latozinemab1件: Latozinemab 💬 1件: SORT1 💬 3件: Cholesterol metabolism, Lysosome, Neurotrophin signaling pathway 💬1件: 127 💬
75Optional prednisone----1件: 127 💬
76Optional sirolimus----1件: 127 💬
77Ossitocina----2件: 127, 193 💬
78Oxytocin1件: Oxytocin1件: Oxytocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬4件: 127, 168, 193, 226 💬
79PBFT021件: PBFT02---1件: 127 💬
80PEA-LUT----1件: 127 💬
81PET/CT----4件: 5, 6, 7, 127 💬
82Phenothiazine1件: Phenothiazine1件: Phenothiazine 💬 --1件: 127 💬
83Pittsburgh compound B1件: Pittsburgh Compound B---1件: 127 💬
84PR006A----1件: 127 💬
85Probiotic1件: Lactobacillus acidophilus1件: Lactomin 💬 --9件: 2, 6, 93, 96, 97, 127, 193, 266, 299 💬
86Recombinant AAV-9 vector expressing THE human progranulin protein----1件: 127 💬
87Rotigotina1件: Rotigotine1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬2件: 6, 127 💬
88Rotigotine1件: Rotigotine1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬3件: 6, 67, 127 💬
89Rotigotine 4MG/24HRS patch1件: Rotigotine1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 127 💬
90Rotigotine 6MG/24HRS patch1件: Rotigotine1件: Rotigotine 💬 1件: DRD2 💬 10件: Alcoholism, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway 💬1件: 127 💬
91Saline nasal mist----1件: 127 💬
92Synthetic stereopure antisense oligonucleotide targeting human C9orf72 hexanucleotide repeat-containing mrna transcripts----2件: 2, 127 💬
93Syntocinon----2件: 127, 193 💬
94T807----1件: 127 💬
95TBC----4件: 85, 94, 96, 127 💬
96THK-53511件: THK-5351---5件: 5, 6, 7, 17, 127 💬
97Tolcapone1件: Tolcapone1件: Tolcapone 💬 1件: COMT 💬 3件: Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬3件: 6, 28, 127 💬
98TPN-101----3件: 2, 127, 325 💬
99TPN-101, 400 MG/DAY----3件: 2, 5, 127 💬
100TRX0237----1件: 127 💬
101Verdiperstat1件: Verdiperstat1件: Verdiperstat 💬 1件: MPO 💬 5件: Acute myeloid leukemia, Drug metabolism - other enzymes, Neutrophil extracellular trap formation, Phagosome, Transcriptional misregulation in cancer 💬2件: 17, 127 💬
102VES001----1件: 127 💬
103Vizamyl----3件: 5, 7, 127 💬
104Vortioxetine1件: Vortioxetine2件: Vortioxetine ,
Vortioxetine hydrobromide 💬 		7件: HTR1,
HTR3,
HTR3,
HTR3,
HTR3,
HTR3,
SLC6A4 💬 		6件: Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse, Synaptic vesicle cycle, Taste transduction, cAMP signaling pathway 💬2件: 6, 127 💬
105Whole exome sequencing----6件: 2, 6, 65, 120, 127, 149 💬
106Whole genome sequencing----5件: 2, 6, 79, 127, 172 💬
107WVE-004----2件: 2, 127 💬