Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
111C-flumazenil----1件: 206 💬
218F-FTC-146----1件: 206 💬
35-hydroxytryptophan / vitamin B6----1件: 206 💬
4Acamprosate1件: Acamprosate2件: Acamprosate calcium ,
Acamprosate 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬2件: 6, 206 💬
5Acidum ascorbicum D61件: Ascorbic acid1件: Ascorbic acid 💬 --1件: 206 💬
6AF056----1件: 206 💬
7AFQ056----3件: 6, 8, 206 💬
8Alpha-tocopherol1件: Vitamin E1件: Vitamin E 💬 --2件: 49, 206 💬
9Arbaclofen1件: Arbaclofen1件: Arbaclofen 💬 2件: GABBR,
GABBR 💬 		8件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬2件: 13, 206 💬
10Aripiprazole1件: Aripiprazole1件: Aripiprazole 💬 4件: DRD2,
DRD3,
HTR1,
HTR2 💬 		14件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, Taste transduction, cAMP signaling pathway 💬2件: 6, 206 💬
11Ascorbic acid1件: Ascorbic acid1件: Ascorbic acid 💬 --4件: 10, 97, 206, 298 💬
12AZD7325----1件: 206 💬
13Baclofen1件: Baclofen1件: Baclofen 💬 2件: GABBR,
GABBR 💬 		8件: Estrogen signaling pathway, GABAergic synapse, GnRH secretion, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Taste transduction, cAMP signaling pathway 💬7件: 2, 10, 13, 18, 65, 149, 206 💬
14Biological samples----2件: 13, 206 💬
15Blood sample----28件: 2, 3, 8, 13, 34, 46, 49, 51, 53, 61, 65, 66, 67, 84, 88, 96, 97, 107, 113, 127, 195, 206, 235, 274, 280, 288, 294, 299 💬
16BPN14770----1件: 206 💬
17BPN14770/ zatolmilast----1件: 206 💬
18Cannabidiol1件: Cannabidiol1件: Cannabidiol 💬 2件: CNR1,
CNR2 💬 		4件: Neuroactive ligand-receptor interaction, Rap1 signaling pathway, Retrograde endocannabinoid signaling, Thermogenesis 💬18件: 6, 8, 13, 19, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 271 💬
19CBD oral solution----1件: 206 💬
20CCD 1042, MD 9150000, mepalon 1042, SPT316----2件: 152, 206 💬
21Cognitive training----1件: 206 💬
22CTH120----1件: 206 💬
23CX5161件: CX516---1件: 206 💬
24Donepezil1件: Donepezil2件: Donepezil hydrochloride ,
Donepezil 💬 		1件: ACHE 💬 3件: Cholinergic synapse, Glycerophospholipid metabolism, Neuroactive ligand signaling 💬8件: 5, 6, 13, 46, 124, 127, 156, 206 💬
25Egcg1件: Epigallocatechin gallate---6件: 6, 8, 13, 28, 85, 206 💬
26Egcg fontup1件: Epigallocatechin gallate---1件: 206 💬
27Ergoloid mesylate1件: Ergoloid mesylate1件: Ergoloid mesylates 💬 6件: ADRA1A,
ADRA1B,
ADRA1D,
ADRA2A,
ADRA2B,
ADRA2C 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 206 💬
28Flumazenil1件: Flumazenil1件: Flumazenil 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 13, 17, 18, 206 💬
29Gaboxadol1件: Gaboxadol1件: Gaboxadol 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬2件: 201, 206 💬
30Ganaxolone1件: Ganaxolone1件: Ganaxolone 💬 16件: GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRA,
GABRB,
GABRB,
GABRB,
GABRD,
GABRE,
GABRG,
GABRG,
GABRG,
GABRP,
GABRQ 💬 		8件: GABAergic synapse, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction 💬4件: 145, 152, 158, 206 💬
31Language intervention----1件: 206 💬
32Lovastatin1件: Lovastatin1件: Lovastatin 💬 1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬11件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 280, 310 💬
33Lovastatin, then minocycline/lovastatin2件: Lovastatin,
Minocycline		3件: Lovastatin ,
Minocycline hydrochloride ,
Minocycline 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬1件: 206 💬
34Mavoglurant1件: Mavoglurant---2件: 6, 206 💬
35Memantine1件: Memantine2件: Memantine hydrochloride ,
Memantine 💬 		5件: GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		21件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway 💬8件: 2, 6, 8, 13, 49, 127, 205, 206 💬
36Metformin1件: Metformin2件: Metformin hydrochloride ,
Metformin 💬 		2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬23件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 84, 86, 97, 113, 127, 206, 218, 225, 265, 285, 298 💬
37Methylphenidate oral solution1件: Methylphenidate2件: Methylphenidate hydrochloride ,
Methylphenidate 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬1件: 206 💬
38Methylphenidate, fluoxetin, risperidone1件: Methylphenidate2件: Methylphenidate hydrochloride ,
Methylphenidate 💬 		2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬2件: 179, 206 💬
39MG01CI extended-release tablet----1件: 206 💬
40MGLU5 antagonist----1件: 206 💬
41Minocycline1件: Minocycline2件: Minocycline hydrochloride ,
Minocycline 💬 		--14件: 2, 6, 8, 13, 46, 85, 90, 94, 97, 162, 201, 206, 280, 299 💬
42Minocycline hydrochloride1件: Minocycline2件: Minocycline hydrochloride ,
Minocycline 💬 		--4件: 13, 201, 206, 299 💬
43Minocycline, then minocycline/lovastatin2件: Lovastatin,
Minocycline		3件: Lovastatin ,
Minocycline hydrochloride ,
Minocycline 💬 		1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬1件: 206 💬
44NNZ-2566----2件: 156, 206 💬
45NON invasive prenatal diagnosis----3件: 8, 113, 206 💬
46NPL-2009----1件: 206 💬
47OV101----2件: 201, 206 💬
48Oxytocin 24IU1件: Oxytocin1件: Oxytocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 206 💬
49Oxytocin 48IU1件: Oxytocin1件: Oxytocin 💬 1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬1件: 206 💬
50Probiotics----6件: 6, 94, 96, 97, 206, 291 💬
51Psilocybin, 1.5 MG1件: Psilocybin1件: Psilocybin 💬 1件: HTR2 💬 6件: Calcium signaling pathway, Gap junction, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Serotonergic synapse 💬1件: 206 💬
52Riluzole1件: Riluzole1件: Riluzole 💬 14件: GRIA1,
GRIA2,
GRIA3,
GRIA4,
GRIK1,
GRIK2,
GRIK3,
GRIK4,
GRIK5,
GRIN1,
GRIN2A,
GRIN2B,
GRIN2C,
GRIN2D 💬 		24件: Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term depression, Long-term potentiation, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Retrograde endocannabinoid signaling, Spinocerebellar ataxia, Systemic lupus erythematosus, Transcriptional misregulation in cancer, cAMP signaling pathway 💬8件: 2, 3, 5, 8, 13, 17, 203, 206 💬
53RO 491-7523/F18----1件: 206 💬
54RO 491-7523/F19----1件: 206 💬
55RO4917523----1件: 206 💬
56RO4917523 0.5 MG----1件: 206 💬
57RO4917523 1.5 MG----1件: 206 💬
58Roflumilast1件: Roflumilast1件: Roflumilast 💬 4件: PDE4,
PDE4,
PDE4,
PDE4 💬 		4件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬4件: 84, 97, 206, 299 💬
59Sertraline1件: Sertraline2件: Sertraline hydrochloride ,
Sertraline 💬 		1件: SLC6A4 💬 3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬3件: 6, 158, 206 💬
60SPG6011件: SPG601---1件: 206 💬
61STX107----1件: 206 💬
62STX209----1件: 206 💬
63Sugar pill----9件: 5, 6, 49, 67, 70, 86, 90, 206, 210 💬
64Sulindac (HLX-0201), dose strength 11件: Sulindac1件: Sulindac 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206 💬
65Sulindac (HLX-0201), dose strength 21件: Sulindac1件: Sulindac 💬 2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬1件: 206 💬
66Tocopheryl acetate1件: alpha-Tocopherol acetate1件: Tocopherol acetate 💬 --1件: 206 💬
67Vitamin C1件: Ascorbic acid1件: Ascorbic acid 💬 --6件: 10, 192, 206, 210, 211, 212 💬
68Vitamin E1件: Vitamin E1件: Vitamin E 💬 --5件: 2, 19, 20, 90, 206 💬
69Water1件: Water1件: Water 💬 --25件: 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬
70Zatolmilast1件: Zatolmilast1件: Zatolmilast 💬 1件: PDE4 💬 4件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬1件: 206 💬
71Zatolmilast/ BPN147701件: Zatolmilast1件: Zatolmilast 💬 1件: PDE4 💬 4件: Morphine addiction, Parathyroid hormone synthesis, secretion and action, Purine metabolism, cAMP signaling pathway 💬1件: 206 💬
72ZYN002----2件: 203, 206 💬
73ZYN002 - cannabidiol transdermal GEL----1件: 206 💬
74ZYN002 - CBD transdermal GEL----1件: 206 💬
75ZYN002 - transdermal GEL----1件: 206 💬