Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Bosentan1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬11件: 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan 125 MG1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
3Bosentan 62.5 MG1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
4Bosentan administration1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
5Bosentan dispersible tablets1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
6Bosentan group1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
7Bosentan monohydrat1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
8Bosentan monohydrate1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 84, 86, 88 💬
9Bosentan mylan1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 41 💬
10Bosentan, ambrisentan1件: Bosentan (Bosentan monohydrate)2件: Bosentan (Bosentan, Bosentan hydrate, BOSENTAN),
Bosentan (Bosentan) 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
11DUO-therapy with sildenafil + bosentan----1件: 86 💬
12Nirs after bosentan administration----1件: 13 💬
13Sildenafil 20MG and bosentan 62.5MG1件: Sildenafil2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
14Sildenafil singly or IN association with bosentan1件: Sildenafil2件: Sildenafil citrate ,
Sildenafil 💬 		1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬1件: 86 💬
15TCD after bosentan administration----1件: 13 💬