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Showing 1 to 10 of 24 descriptions
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No.
薬物名（臨床試験情報から抽出）
DrugBank
KEGG DRUG
KEGG GENES
KEGG PATHWAY
指定難病告示番号
1
750 mg
metformin
and 7.5 g L-citrulline daily p.o.
2件:
Citrulline
Citrulline
,
Metformin
1件:
Metformin
Metformin
💬
1. 750 mg
metformin
and 7.5 g L-citrulline daily p.o.
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
1. 750 mg
metformin
and 7.5 g L-citrulline daily p.o.
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
113
113
💬
1. 750 mg
metformin
and 7.5 g L-citrulline daily p.o.
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
2
Glucophage (
metformin
)
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
2. Glucophage (
metformin
)
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
2. Glucophage (
metformin
)
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
2件:
46
46
,
75
💬
2. Glucophage (
metformin
)
×
告示番号
日本語名
英語名
46
悪性関節リウマチ
Malignant rheumatoid arthritis
75
クッシング病
Cushing disease
3
L-Citrulline and
Metformin
& L-Citrulline
2件:
Citrulline
Citrulline
,
Metformin
1件:
Metformin
Metformin
💬
3. L-Citrulline and
Metformin
& L-Citrulline
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
3. L-Citrulline and
Metformin
& L-Citrulline
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
113
113
💬
3. L-Citrulline and
Metformin
& L-Citrulline
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
4
Metformin
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
4.
Metformin
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
4.
Metformin
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
25件:
2
2
,
6
,
8
,
13
,
46
,
49
,
60
,
65
,
67
,
75
,
77
,
81
,
86
,
97
,
113
,
127
,
158
,
206
,
218
,
225
,
233
,
265
,
285
,
299
,
301
💬
25件:
2
,
6
,
8
,
13
,
46
,
49
,
60
,
65
,
67
,
75
,
77
,
81
,
86
,
97
,
113
,
127
,
158
,
206
,
218
,
225
,
233
,
265
,
28
...
4.
Metformin
×
告示番号
日本語名
英語名
2
筋萎縮性側索硬化症
Amyotrophic lateral sclerosis
6
パーキンソン病
Parkinson disease
8
ハンチントン病
Huntington disease
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
46
悪性関節リウマチ
Malignant rheumatoid arthritis
49
全身性エリテマトーデス
Systemic lupus erythematosus
60
再生不良性貧血
Aplastic anemia
65
原発性免疫不全症候群
Primary immunodeficiency
67
多発性嚢胞腎
Polycystic kidney disease
75
クッシング病
Cushing disease
77
下垂体性成長ホルモン分泌亢進症
Growth hormone secreting pituitary adenoma
81
先天性副腎皮質酵素欠損症
Congenital adrenal hyperplasia
86
肺動脈性肺高血圧症
Pulmonary arterial hypertension
97
潰瘍性大腸炎
Ulcerative colitis
113
筋ジストロフィー
Muscular dystrophy
127
前頭側頭葉変性症
Frontotemporal lobar degeneration
158
結節性硬化症
Tuberous sclerosis
206
脆弱Ｘ症候群
Fragile X syndrome
218
アルポート症候群
Alport syndrome
225
先天性腎性尿崩症;遺伝性腎性尿崩症
Congenital nephrogenic diabetes insipidus
233
ウォルフラム症候群
Wolfram syndrome
265
脂肪萎縮症
Lipodystrophy
285
ファンコニ貧血
Fanconi anemia
299
嚢胞性線維症;膵囊胞線維症
Cystic fibrosis
301
黄斑ジストロフィー
Macular dystrophy
5
Metformin
(generic)
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
5.
Metformin
(generic)
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
5.
Metformin
(generic)
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
158
158
💬
5.
Metformin
(generic)
×
告示番号
日本語名
英語名
158
結節性硬化症
Tuberous sclerosis
6
MetFORMIN
1000 Mg Oral Tablet
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
6.
MetFORMIN
1000 Mg Oral Tablet
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
6.
MetFORMIN
1000 Mg Oral Tablet
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
13
13
💬
6.
MetFORMIN
1000 Mg Oral Tablet
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
7
Metformin
500 Mg Oral Tablet, up to 4 tablets a day
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
7.
Metformin
500 Mg Oral Tablet, up to 4 tablets a day
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
7.
Metformin
500 Mg Oral Tablet, up to 4 tablets a day
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
13
13
💬
7.
Metformin
500 Mg Oral Tablet, up to 4 tablets a day
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica
8
Metformin
500 mg TID Oral Tablet
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
8.
Metformin
500 mg TID Oral Tablet
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
8.
Metformin
500 mg TID Oral Tablet
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
97
97
💬
8.
Metformin
500 mg TID Oral Tablet
×
告示番号
日本語名
英語名
97
潰瘍性大腸炎
Ulcerative colitis
9
Metformin
500mg
1件:
Metformin
Metformin
1件:
Metformin
Metformin
💬
9.
Metformin
500mg
×
Name
Other Names
Metformin
Metformin (USAN/INN)
メトホルミン
2件:
PRKAA1
PRKAA1
,
PRKAA2
💬
9.
Metformin
500mg
×
Name
Full Name
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
20件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
20件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
113
113
💬
9.
Metformin
500mg
×
告示番号
日本語名
英語名
113
筋ジストロフィー
Muscular dystrophy
10
Metformin
and clemastine in combination
2件:
Clemastine
Clemastine
,
Metformin
2件:
Clemastine
Clemastine
,
Metformin
💬
10.
Metformin
and clemastine in combination
×
Name
Other Names
Clemastine
Clemastine (USAN)
クレマスチン
Metformin
Metformin (USAN/INN)
メトホルミン
3件:
HRH1
HRH1
,
PRKAA1
,
PRKAA2
💬
10.
Metformin
and clemastine in combination
×
Name
Full Name
HRH1
histamine receptor H1
PRKAA1
protein kinase AMP-activated catalytic subunit alpha 1
PRKAA2
protein kinase AMP-activated catalytic subunit alpha 2
23件:
AMPK signaling pathway
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signaling pathway
,
Autophagy - animal
,
Calcium signaling pathway
,
Circadian rhythm
,
Fluid shear stress and atherosclerosis
,
FoxO signaling pathway
,
Glucagon signaling pathway
,
Hypertrophic cardiomyopathy
,
Inflammatory mediator regulation of TRP channels
,
Insulin resistance
,
Insulin signaling pathway
,
Longevity regulating pathway
,
Longevity regulating pathway - multiple species
,
Neuroactive ligand-receptor interaction
,
Non-alcoholic fatty liver disease
,
Oxytocin signaling pathway
,
PI3K-Akt signaling pathway
,
Thermogenesis
,
Tight junction
,
mTOR signaling pathway
💬
23件:
AMPK signaling pathway
,
Adipocytokine signaling pathway
,
Alcoholic liver disease
,
Apelin signal
...
1件:
13
13
💬
10.
Metformin
and clemastine in combination
×
告示番号
日本語名
英語名
13
多発性硬化症／視神経脊髄炎
Multiple sclerosis/Neuromyelitis optica