Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine hydrochloride 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
2 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Fexofenadine 💬 Fexofenadine 4件: 6, 13, 19, 46 💬
3 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine 💬 Promethazine 2件: 6, 96 💬
4 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine citrate 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
5 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine 💬 Clemastine 2件: 13, 179 💬
6 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Clemastine fumarate 💬 Clemastine 2件: 13, 179 💬
7 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
8 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine hydrochloride 💬 Chlorpromazine 2件: 120, 254 💬
9 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpromazine 💬 Chlorpromazine 2件: 120, 254 💬
10 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine 💬 Olanzapine 2件: 2, 8 💬
11 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Desloratadine 💬 Desloratadine 3件: 13, 46, 97 💬
12 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Loratadine 💬 Loratadine 5件: 13, 19, 46, 89, 98 💬
13 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine teoclate 💬 Promethazine 2件: 6, 96 💬
14 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Promethazine hydrochloride 💬 Promethazine 2件: 6, 96 💬
15 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine 💬 Rupatadine 2件: 46, 97 💬
16 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Dexchlorpheniramine 💬 Dexchlorpheniramine 2件: 13, 49 💬
17 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Diphenhydramine salicylate 💬 Diphenhydramine 12件: 11, 13, 19, 49, 51, 63, 70, 86, 96, 222, 256, 300 💬
18 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Fexofenadine hydrochloride 💬 Fexofenadine 4件: 6, 13, 19, 46 💬
19 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Histamine 💬 Histamine 1件: 13 💬
20 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Doxepin hydrochloride 💬 Doxepin 1件: 6 💬
21 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Rupatadine fumarate 💬 Rupatadine 2件: 46, 97 💬
22 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Cetirizine 💬 Cetirizine 3件: 13, 19, 35 💬
23 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Doxepin 💬 Doxepin 1件: 6 💬
24 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Cetirizine hydrochloride 💬 Cetirizine 3件: 13, 19, 35 💬
25 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Olanzapine pamoate 💬 Olanzapine 2件: 2, 8 💬
26 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Histamine phosphate 💬 Histamine 1件: 13 💬