Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Bosentan
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan (Tracleer)1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
3Bosentan 125 mg
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
4Bosentan 62.5 mg
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
5Bosentan administration
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
6Bosentan and dapagliflozin
(Tracleer)		2件: Bosentan,
Dapagliflozin		3件: Bosentan (Tracleer),
Bosentan ,
Dapagliflozin 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 40, 41 💬
7Bosentan Dispersible Tablets
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
8Bosentan group
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
9Bosentan monohydrat
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
10BOSENTAN MONOHYDRATE
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 84, 86, 88 💬
11BOSENTAN MYLAN
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 41 💬
12Bosentan, Ambrisentan
(Tracleer)		2件: Ambrisentan,
Bosentan		3件: Bosentan (Tracleer),
Ambrisentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
13Duo-Therapy with Sildenafil + Bosentan
(Tracleer)		2件: Bosentan,
Sildenafil		4件: Bosentan (Tracleer),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(Tracleer)		4件: Bosentan,
Macitentan,
Sildenafil,
Tadalafil		6件: Bosentan (Tracleer),
Tadalafil ,
Sildenafil citrate ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
15NIRS after bosentan administration
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
16Observational study with patients treated with Tracleer, Ventavis, Veletri, Opsumit and/or Uptravi----1件: 86 💬
17Other: Switch from Ambrisentan to Bosentan
(Tracleer)		2件: Ambrisentan,
Bosentan		3件: Bosentan (Tracleer),
Ambrisentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
18Sildenafil 20mg and Bosentan 62.5mg
(Tracleer)		2件: Bosentan,
Sildenafil		4件: Bosentan (Tracleer),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
19Sildenafil singly or in association with Bosentan
(Tracleer)		2件: Bosentan,
Sildenafil		4件: Bosentan (Tracleer),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
20TCD after bosentan administration
(Tracleer)		1件: Bosentan2件: Bosentan (Tracleer),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
21Tracleer----8件: 13, 51, 84, 85, 86, 88, 210, 211 💬
22TRACLEER 125MG 56CPR RIV.----1件: 88 💬
23TRACLEER 62,5MG 56CPR RIV.----1件: 86 💬
24Tracleer Tablet for Oral Suspension----1件: 86 💬
25TRACLEER*125MG 56CPR RIV.----2件: 51, 86 💬
26TRACLEER*56CPR RIV 125MG----3件: 51, 86, 88 💬
27Tracleer®----1件: 86 💬