Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. 薬物名（臨床試験情報から抽出） DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY 指定難病告示番号
1Bosentan
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬12件: 13, 40, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
2Bosentan (Tracleer)
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
3Bosentan 125 mg
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
4Bosentan 62.5 mg
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
5Bosentan administration
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
6Bosentan and dapagliflozin
(D01227)		2件: Bosentan,
Dapagliflozin		3件: Bosentan (D01227),
Bosentan ,
Dapagliflozin 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 40, 41 💬
7Bosentan Dispersible Tablets
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
8Bosentan group
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 51 💬
9Bosentan monohydrat
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
10BOSENTAN MONOHYDRATE
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 84, 86, 88 💬
11BOSENTAN MYLAN
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 41 💬
12Bosentan, Ambrisentan
(D01227)		2件: Ambrisentan,
Bosentan		3件: Bosentan (D01227),
Ambrisentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
13Duo-Therapy with Sildenafil + Bosentan
(D01227)		2件: Bosentan,
Sildenafil		4件: Bosentan (D01227),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
14ERA and PDE-5I (Sildenafil, Tadalafil, Bosentan, Macitentan)
(D01227)		4件: Bosentan,
Macitentan,
Sildenafil,
Tadalafil		6件: Bosentan (D01227),
Tadalafil ,
Sildenafil citrate ,
Bosentan ,
Sildenafil ,
Macitentan 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
15NIRS after bosentan administration
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
16Other: Switch from Ambrisentan to Bosentan
(D01227)		2件: Ambrisentan,
Bosentan		3件: Bosentan (D01227),
Ambrisentan ,
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
17Sildenafil 20mg and Bosentan 62.5mg
(D01227)		2件: Bosentan,
Sildenafil		4件: Bosentan (D01227),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 51, 86 💬
18Sildenafil singly or in association with Bosentan
(D01227)		2件: Bosentan,
Sildenafil		4件: Bosentan (D01227),
Sildenafil citrate ,
Bosentan ,
Sildenafil 💬 		3件: EDNRA,
EDNRB,
PDE5A 💬 		10件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Purine metabolism, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 86 💬
19TCD after bosentan administration
(D01227)		1件: Bosentan2件: Bosentan (D01227),
Bosentan 💬 		2件: EDNRA,
EDNRB 💬 		9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬