Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Acetazolamide 💬1件: Acetazolamide1件: Acetazolamide13件: CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA2,
CA4 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬5件: 13, 90, 115, 155, 230 💬
2 Acetazolamide sodium 💬1件: Acetazolamide1件: Acetazolamide13件: CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA,
CA2,
CA4 💬 		6件: Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬5件: 13, 90, 115, 155, 230 💬
3 Amiloride 💬1件: Amiloride2件: Amiloride; Amiloride hydrochloride3件: SCNN1A,
SCNN1B,
SCNN1G 💬 		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299 💬
4 Amiloride hydrochloride 💬1件: Amiloride2件: Amiloride; Amiloride hydrochloride3件: SCNN1A,
SCNN1B,
SCNN1G 💬 		2件: Aldosterone-regulated sodium reabsorption, Taste transduction 💬4件: 13, 67, 225, 299 💬
5 Arginine 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
6 Arginine hydrochloride 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
7 Arginine hydrochloride 💬1件: Arginine1件: Arginine--3件: 72, 225, 251 💬
8 Atorvastatin 💬1件: Atorvastatin2件: Atorvastatin; Atorvastatin calcium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬18件: 13, 22, 46, 49, 51, 58, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
9 Atorvastatin calcium 💬1件: Atorvastatin2件: Atorvastatin; Atorvastatin calcium1件: HMGCR 💬 3件: AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬18件: 13, 22, 46, 49, 51, 58, 79, 84, 88, 93, 96, 97, 160, 225, 265, 271, 297, 299 💬
10 Chlorothiazide 💬1件: Chlorothiazide1件: Chlorothiazide1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬1件: 225 💬
11 Chlorothiazide sodium 💬1件: Chlorothiazide1件: Chlorothiazide1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬1件: 225 💬
12 Desmopressin 💬1件: Desmopressin4件: Ddavp; Desmopressin; Desmopressin acetate; Desmopressine2件: AVPR2,
F8 💬 		5件: Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 64, 75, 225, 288 💬
13 Desmopressin acetate 💬1件: Desmopressin4件: Ddavp; Desmopressin; Desmopressin acetate; Desmopressine2件: AVPR2,
F8 💬 		5件: Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 64, 75, 225, 288 💬
14 Fluconazole 💬1件: Fluconazole2件: Diflucan; Fluconazole--2件: 96, 225 💬
15 Hydrochlorothiazide 💬1件: Hydrochlorothiazide1件: Hydrochlorothiazide1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬4件: 13, 67, 225, 235 💬
16 Indomethacin 💬1件: Indomethacin2件: Indometacin; Indomethacin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
17 Indomethacin sodium 💬1件: Indomethacin2件: Indometacin; Indomethacin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
18 Metformin 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
19 Metformin hydrochloride 💬1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
20 Omeprazole 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
21 Omeprazole magnesium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
22 Omeprazole sodium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
23 Riociguat 💬1件: Riociguat1件: Riociguat3件: GUCY1A,
GUCY1A,
GUCY1B 💬 		10件: Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬6件: 51, 84, 86, 88, 225, 299 💬
24 Sevoflurane 💬1件: Sevoflurane1件: Sevoflurane--8件: 6, 21, 22, 34, 70, 98, 225, 296 💬
25 Sildenafil 💬1件: Sildenafil3件: Sildenafil; Sildenafil citrate; Sildenafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
26 Sildenafil citrate 💬1件: Sildenafil3件: Sildenafil; Sildenafil citrate; Sildenafilo1件: PDE5 💬 2件: Purine metabolism, cGMP-PKG signaling pathway 💬14件: 6, 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
27 Spironolactone 💬1件: Spironolactone1件: Spironolactone1件: NR3C2 💬 1件: Aldosterone-regulated sodium reabsorption 💬7件: 46, 58, 67, 86, 113, 210, 225 💬
28 Tolvaptan 💬1件: Tolvaptan1件: Tolvaptan1件: AVPR2 💬 4件: Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬4件: 67, 72, 86, 225 💬
29 Vasopressin 💬1件: Vasopressin1件: Vasopressin3件: AVPR1A,
AVPR1B,
AVPR2 💬 		6件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬2件: 210, 225 💬
30 Water 💬1件: Water1件: Water--25件: 2, 5, 6, 13, 17, 19, 22, 46, 51, 53, 56, 57, 63, 64, 66, 67, 85, 96, 97, 206, 226, 230, 274, 278, 299 💬