Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Ianalumab 💬1件: Ianalumab1件: Ianalumab1件: TNFRSF13C 💬 5件: Cytokine-cytokine receptor interaction, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Primary immunodeficiency 💬8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
2 Ibandronate sodium 💬1件: Ibandronate2件: Ibandronate; Ibandronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬2件: 46, 274 💬
3 Ibandronic acid 💬1件: Ibandronate2件: Ibandronate; Ibandronic acid1件: FDPS 💬 3件: Human T-cell leukemia virus 1 infection, Influenza A, Terpenoid backbone biosynthesis 💬2件: 46, 274 💬
4 Ibrutinib 💬1件: Ibrutinib1件: Ibrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬3件: 28, 60, 61 💬
5 Ibudilast 💬1件: Ibudilast1件: Ibudilast8件: CYSLTR1,
PDE3A,
PDE3B,
PDE4,
PDE4,
PDE4,
PDE4,
PTGIR 💬 		15件: Apelin signaling pathway, Calcium signaling pathway, Glucagon signaling pathway, Insulin signaling pathway, Morphine addiction, Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Platelet activation, Progesterone-mediated oocyte maturation, Purine metabolism, Regulation of lipolysis in adipocytes, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 13 💬
6 Ibuprofen 💬1件: Ibuprofen1件: Ibuprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
7 Ibuprofen aluminum 💬1件: Ibuprofen1件: Ibuprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
8 Ibuprofen lysine 💬1件: Ibuprofen1件: Ibuprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
9 Ibuprofen sodium 💬1件: Ibuprofen1件: Ibuprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
10 Ibuprofen sodium 💬1件: Ibuprofen1件: Ibuprofen2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬6件: 13, 46, 65, 113, 271, 299 💬
11 Icatibant acetate 💬1件: Icatibant2件: Icatibant; Icatibant acetate1件: BDKRB2 💬 10件: Calcium signaling pathway, Chagas disease, Complement and coagulation cascades, Endocrine and other factor-regulated calcium reabsorption, Inflammatory mediator regulation of TRP channels, Neuroactive ligand-receptor interaction, Pathways in cancer, Regulation of actin cytoskeleton, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬1件: 65 💬
12 Icosapent 💬1件: Icosapent1件: Eicosapentaenoic acid--6件: 49, 96, 97, 296, 297, 338 💬
13 Icosapent ethyl 💬1件: Icosapent ethyl1件: Ethyl-EPA--1件: 8 💬
14 Icotinib 💬1件: Icotinib1件: Icotinib1件: EGFR 💬 47件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Choline metabolism in cancer, Colorectal cancer, Coronavirus disease - COVID-19, Cushing syndrome, Endocytosis, Endometrial cancer, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Estrogen signaling pathway, Focal adhesion, FoxO signaling pathway, Gap junction, Gastric cancer, Glioma, GnRH signaling pathway, HIF-1 signaling pathway, Hepatitis C, Hepatocellular carcinoma, Human cytomegalovirus infection, Human papillomavirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, Non-small cell lung cancer, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Relaxin signaling pathway, Shigellosis, Virion - Hepatitis viruses 💬1件: 34 💬
15 Idebenone 💬1件: Idebenone1件: Idebenone--7件: 6, 8, 13, 18, 21, 113, 302 💬
16 Idecabtagene vicleucel 💬1件: Idecabtagene vicleucel1件: Idecabtagene vicleucel1件: TNFRSF17 💬 2件: Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production 💬1件: 28 💬
17 Idursulfase 💬1件: Idursulfase2件: Idursulfasa; Idursulfase1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
18 Idursulfase beta 💬1件: Idursulfase beta2件: Hunterase; Idursulfase beta1件: IDS 💬 2件: Glycosaminoglycan degradation, Lysosome 💬1件: 19 💬
19 Ifenprodil 💬1件: Ifenprodil1件: Ifenprodil3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13 💬
20 Ifenprodil tartrate 💬1件: Ifenprodil1件: Ifenprodil3件: ADRA1A,
ADRA1B,
ADRA1D 💬 		9件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬1件: 13 💬
21 Ifetroban 💬1件: Ifetroban2件: Ifetroban; Ifetroban sodium1件: TBXA2R 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬2件: 85, 113 💬
22 Ifetroban sodium 💬1件: Ifetroban2件: Ifetroban; Ifetroban sodium1件: TBXA2R 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Platelet activation 💬2件: 85, 113 💬
23 Ifosfamide 💬1件: Ifosfamide1件: Ifosfamide--1件: 34 💬
24 Iguratimod 💬1件: Iguratimod1件: Iguratimod1件: NFKB1 💬 75件: AGE-RAGE signaling pathway in diabetic complications, Acute myeloid leukemia, Adipocytokine signaling pathway, Alcoholic liver disease, Alzheimer disease, Amoebiasis, Apoptosis, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Chemical carcinogenesis - reactive oxygen species, Chemical carcinogenesis - receptor activation, Chemokine signaling pathway, Chronic myeloid leukemia, Cocaine addiction, Coronavirus disease - COVID-19, Cytosolic DNA-sensing pathway, Diabetic cardiomyopathy, Epithelial cell signaling in Helicobacter pylori infection, Epstein-Barr virus infection, Fluid shear stress and atherosclerosis, HIF-1 signaling pathway, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, Longevity regulating pathway, MAPK signaling pathway, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Neurotrophin signaling pathway, Neutrophil extracellular trap formation, Non-alcoholic fatty liver disease, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prolactin signaling pathway, Prostate cancer, RIG-I-like receptor signaling pathway, Ras signaling pathway, Relaxin signaling pathway, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, T cell receptor signaling pathway, TNF signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Tuberculosis, Viral carcinogenesis, Yersinia infection, cAMP signaling pathway 💬6件: 46, 49, 51, 53, 271, 300 💬
25 Ilofotase alfa 💬1件: Recombinant human alkaline phosphatase0件: 1件: E3.1.3.1 💬 2件: Folate biosynthesis, Thiamine metabolism 💬-
26 Iloperidone 💬1件: Iloperidone1件: Iloperidone4件: DRD2,
HTR2,
HTR2,
HTR2 💬 		13件: Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Serotonergic synapse, cAMP signaling pathway 💬1件: 6 💬
27 Iloprost 💬1件: Iloprost1件: Iloprost1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬4件: 51, 84, 85, 86 💬
28 Iloprost tromethamine 💬1件: Iloprost1件: Iloprost1件: PTGIR 💬 3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction 💬4件: 51, 84, 85, 86 💬
29 Imatinib 💬1件: Imatinib2件: Imatinib; Imatinib mesylate3件: ABL1,
KIT,
PDGFRA 💬 		31件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬10件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 162 💬
30 Imatinib mesylate 💬1件: Imatinib2件: Imatinib; Imatinib mesylate3件: ABL1,
KIT,
PDGFRA 💬 		31件: Acute myeloid leukemia, Axon guidance, Breast cancer, Calcium signaling pathway, Cell cycle, Central carbon metabolism in cancer, Chemical carcinogenesis - reactive oxygen species, Choline metabolism in cancer, Chronic myeloid leukemia, Endocytosis, ErbB signaling pathway, Focal adhesion, Gap junction, Glioma, Hematopoietic cell lineage, Human cytomegalovirus infection, JAK-STAT signaling pathway, MAPK signaling pathway, Melanogenesis, Melanoma, MicroRNAs in cancer, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Phospholipase D signaling pathway, Prostate cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Viral myocarditis 💬10件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 162 💬
31 Imidapril 💬1件: Imidapril1件: Imidapril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 67 💬
32 Imidapril hydrochloride 💬1件: Imidapril1件: Imidapril1件: ACE 💬 6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system 💬1件: 67 💬
33 Imiglucerase 💬1件: Imiglucerase2件: Imiglucerasa; Imiglucerase1件: GBA 💬 4件: Cornified envelope formation, Lysosome, Other glycan degradation, Sphingolipid metabolism 💬1件: 19 💬
34 Imipenem 💬1件: Imipenem0件: ---
35 Imipenem 💬1件: Imipenem0件: ---
36 Imiquimod 💬1件: Imiquimod0件: 1件: TLR7 💬 5件: Coronavirus disease - COVID-19, Influenza A, Measles, Neutrophil extracellular trap formation, Toll-like receptor signaling pathway 💬-
37 Imlifidase 💬1件: Imlifidase3件: HMED-ides; Ides; Imlifidase--5件: 43, 44, 64, 113, 221 💬
38 Imsidolimab 💬1件: Imsidolimab1件: Imsidolimab1件: IL1RL2 💬 1件: Cytokine-cytokine receptor interaction 💬1件: 37 💬
39 Imvotamab 💬1件: Imvotamab1件: Imvotamab2件: CD3E,
MS4A1 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬2件: 46, 49 💬
40 Inclisiran 💬1件: Inclisiran3件: ALN-pcssc; Inclisiran; Inclisiran sodium1件: PCSK9 💬 1件: Cholesterol metabolism 💬1件: 79 💬
41 Inclisiran sodium 💬1件: Inclisiran3件: ALN-pcssc; Inclisiran; Inclisiran sodium1件: PCSK9 💬 1件: Cholesterol metabolism 💬1件: 79 💬
42 Indapamide 💬1件: Indapamide0件: 1件: SLC12A3 💬 1件: Parathyroid hormone synthesis, secretion and action 💬-
43 Indinavir 💬1件: Indinavir1件: Indinavir--1件: 265 💬
44 Indinavir sulfate 💬1件: Indinavir1件: Indinavir--1件: 265 💬
45 Indinavir sulfate ethanolate 💬1件: Indinavir1件: Indinavir--1件: 265 💬
46 Indocyanine green 💬1件: Indocyanine green1件: Indocyanine green--8件: 22, 46, 51, 96, 235, 278, 291, 296 💬
47 Indomethacin 💬1件: Indomethacin2件: Indometacin; Indomethacin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
48 Indomethacin sodium 💬1件: Indomethacin2件: Indometacin; Indomethacin2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 225, 271, 298 💬
49 Inebilizumab 💬1件: Inebilizumab1件: Inebilizumab1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬6件: 11, 13, 46, 49, 51, 300 💬
50 Infigratinib 💬1件: Infigratinib2件: Infigratinib; Infigratinib phosphate3件: FGFR1,
FGFR2,
FGFR3 💬 		20件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Endocytosis, Gastric cancer, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells, Thermogenesis 💬1件: 276 💬
51 Infigratinib phosphate 💬1件: Infigratinib2件: Infigratinib; Infigratinib phosphate3件: FGFR1,
FGFR2,
FGFR3 💬 		20件: Adherens junction, Bladder cancer, Breast cancer, Calcium signaling pathway, Central carbon metabolism in cancer, Endocytosis, Gastric cancer, MAPK signaling pathway, Melanoma, MicroRNAs in cancer, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Regulation of actin cytoskeleton, Signaling pathways regulating pluripotency of stem cells, Thermogenesis 💬1件: 276 💬
52 Infliximab 💬1件: Infliximab1件: Infliximab1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬24件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 164, 269, 270, 271 💬
53 Inosine 💬1件: Inosine1件: Inosine--4件: 2, 6, 13, 122 💬
54 Inositol 💬1件: Inositol1件: Inositol--2件: 96, 97 💬
55 Inotersen 💬1件: Inotersen1件: Inotersen1件: TTR 💬 1件: Thyroid hormone synthesis 💬1件: 28 💬
56 Inotersen sodium 💬1件: Inotersen1件: Inotersen1件: TTR 💬 1件: Thyroid hormone synthesis 💬1件: 28 💬
57 Insulin detemir 💬1件: Insulin detemir0件: 1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬-
58 Insulin glargine 💬1件: Insulin glargine1件: Insulin glargine1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 299 💬
59 Insulin human 💬1件: Insulin human1件: Human insulin1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 156 💬
60 Insulin lispro 💬1件: Insulin lispro1件: Insulin lispro1件: INSR 💬 23件: AMPK signaling pathway, Adherens junction, Aldosterone-regulated sodium reabsorption, Alzheimer disease, Diabetic cardiomyopathy, FoxO signaling pathway, HIF-1 signaling pathway, Hormone signaling, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Non-alcoholic fatty liver disease, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Phospholipase D signaling pathway, Rap1 signaling pathway, Ras signaling pathway, Regulation of lipolysis in adipocytes, Type II diabetes mellitus, cGMP-PKG signaling pathway, mTOR signaling pathway 💬1件: 53 💬
61 Interferon alfa 💬1件: Interferon alfa0件: 2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬-
62 Interferon alfa-2a 💬1件: Interferon alfa-2a2件: Interferon ALFA-2A; Interferon alpha-2A2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 56 💬
63 Interferon alfa-2b 💬1件: Interferon alfa-2b1件: Interferon ALFA-2B2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 25 💬
64 Interferon beta 💬1件: Human interferon beta3件: Human interferon beta; Interferon beta; Interferon-beta2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 13, 20, 50 💬
65 Interferon beta-1a 💬1件: Interferon beta-1a4件: Interferon beta 1-A; Interferon beta 1A; Interferon BETA-1A; Interferon-BETA-1A2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬3件: 13, 96, 97 💬
66 Interferon beta-1b 💬1件: Interferon beta-1b3件: Interferon beta 1B; Interferon BETA-1B; Interferon-BETA-1B2件: IFNAR1,
IFNAR2 💬 		18件: Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Measles, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PI3K-Akt signaling pathway, Pathways in cancer, Toll-like receptor signaling pathway 💬1件: 13 💬
67 Interferon gamma-1b 💬1件: Interferon gamma-1b1件: Interferon gamma-1B2件: IFNGR1,
IFNGR2 💬 		18件: Chagas disease, Cytokine-cytokine receptor interaction, HIF-1 signaling pathway, Herpes simplex virus 1 infection, Inflammatory bowel disease, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Natural killer cell mediated cytotoxicity, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways in cancer, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis 💬7件: 18, 65, 85, 228, 299, 301, 326 💬
68 Inulin 💬1件: Inulin1件: Inulin--2件: 6, 299 💬
69 Iodine 💬1件: Iodine1件: Iodine--3件: 28, 46, 96 💬
70 Ioflupane I 123 💬1件: Ioflupane I-1232件: Ioflupane; Ioflupane I 1231件: SLC6A3 💬 8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬1件: 6 💬
71 Iohexol 💬1件: Iohexol1件: Iohexol--2件: 19, 67 💬
72 Ipilimumab 💬1件: Ipilimumab1件: Ipilimumab1件: CTLA4 💬 4件: Autoimmune thyroid disease, Cell adhesion molecules, Rheumatoid arthritis, T cell receptor signaling pathway 💬1件: 159 💬
73 Iproniazid 💬1件: Iproniazid1件: Iproniazid2件: MAO,
MAO 💬 		13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6 💬
74 Iproniazid phosphate 💬1件: Iproniazid1件: Iproniazid2件: MAO,
MAO 💬 		13件: Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Glycine, serine and threonine metabolism, Histidine metabolism, Parkinson disease, Phenylalanine metabolism, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism 💬1件: 6 💬
75 Iptacopan 💬1件: Iptacopan1件: Iptacopan1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
76 Iptacopan hydrochloride 💬1件: Iptacopan1件: Iptacopan1件: CFB 💬 3件: Complement and coagulation cascades, Coronavirus disease - COVID-19, Staphylococcus aureus infection 💬6件: 11, 61, 62, 66, 109, 222 💬
77 Irbesartan 💬1件: Irbesartan1件: Irbesartan1件: AGTR1 💬 17件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Hormone signaling, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬4件: 66, 167, 168, 222 💬
78 Iron dextran 💬1件: Iron Dextran1件: Iron dextran--2件: 62, 97 💬
79 Iron sucrose 💬1件: Iron sucrose1件: Iron sucrose--3件: 62, 96, 97 💬
80 Isatuximab 💬1件: Isatuximab1件: Isatuximab1件: CD38 💬 6件: Calcium signaling pathway, Hematopoietic cell lineage, Nicotinate and nicotinamide metabolism, Oxytocin signaling pathway, Pancreatic secretion, Salivary secretion 💬3件: 28, 61, 283 💬
81 Iscalimab 💬1件: Iscalimab1件: Iscalimab1件: TNFRSF5 💬 17件: Allograft rejection, Asthma, Autoimmune thyroid disease, Cell adhesion molecules, Cytokine-cytokine receptor interaction, Epstein-Barr virus infection, Human T-cell leukemia virus 1 infection, Intestinal immune network for IgA production, Lipid and atherosclerosis, Malaria, NF-kappa B signaling pathway, Primary immunodeficiency, Systemic lupus erythematosus, Toll-like receptor signaling pathway, Toxoplasmosis, Transcriptional misregulation in cancer, Viral myocarditis 💬2件: 49, 53 💬
82 Isoflurane 💬1件: Isoflurane1件: Isoflurane--1件: 6 💬
83 Isoleucine 💬1件: Isoleucine1件: Isoleucine--1件: 244 💬
84 Isoniazid 💬1件: Isoniazid1件: Isoniazid--1件: 254 💬
85 Isopropanol and methylated alcohol 💬1件: Ethanol2件: Alcohol; Ethanol--5件: 58, 97, 279, 280, 285 💬
86 Isopropyl unoprostone 💬1件: Unoprostone1件: Unoprostone1件: PTGFR 💬 3件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway 💬1件: 90 💬
87 Isosorbide 💬1件: Isosorbide0件: ---
88 Isosorbide dinitrate 💬1件: Isosorbide dinitrate0件: ---
89 Isotretinoin 💬1件: Isotretinoin1件: Isotretinoin2件: RARA,
RARB 💬 		8件: Acute myeloid leukemia, Estrogen signaling pathway, Gastric cancer, Non-small cell lung cancer, Pathways in cancer, Small cell lung cancer, Th17 cell differentiation, Transcriptional misregulation in cancer 💬4件: 36, 39, 159, 160 💬
90 Isoxsuprine 💬1件: Isoxsuprine1件: Isoxsuprine hydrochloride1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
91 Isoxsuprine hydrochloride 💬1件: Isoxsuprine1件: Isoxsuprine hydrochloride1件: ADRB2 💬 11件: Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Chemical carcinogenesis - receptor activation, Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 13 💬
92 Isradipine 💬1件: Isradipine1件: Isradipine4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬1件: 6 💬
93 Istradefylline 💬1件: Istradefylline1件: Istradefylline1件: ADORA2A 💬 8件: Alcoholism, Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Vascular smooth muscle contraction, cAMP signaling pathway 💬1件: 6 💬
94 Itacitinib 💬1件: Itacitinib2件: Itacitinib; Itacitinib adipate1件: JAK1 💬 27件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬4件: 46, 51, 97, 228 💬
95 Itacitinib adipate 💬1件: Itacitinib2件: Itacitinib; Itacitinib adipate1件: JAK1 💬 27件: Coronavirus disease - COVID-19, Epstein-Barr virus infection, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Viral carcinogenesis 💬4件: 46, 51, 97, 228 💬
96 Itepekimab 💬1件: Itepekimab1件: Itepekimab1件: IL33 💬 4件: Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Influenza A, Necroptosis 💬1件: 299 💬
97 Itolizumab 💬1件: Itolizumab1件: Itolizumab1件: CD6 💬 1件: Cell adhesion molecules 💬2件: 49, 50 💬
98 Itraconazole 💬1件: Itraconazole1件: Itraconazole--7件: 2, 3, 65, 96, 97, 227, 299 💬
99 Ivacaftor 💬1件: Ivacaftor1件: Ivacaftor1件: CFTR 💬 8件: ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway 💬2件: 299, 340 💬
100 Ixazomib 💬1件: Ixazomib2件: Ixazomib; Ixazomib citrate1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬3件: 16, 28, 51 💬
101 Ixazomib citrate 💬1件: Ixazomib2件: Ixazomib; Ixazomib citrate1件: PSMB5 💬 8件: Alzheimer disease, Amyotrophic lateral sclerosis, Huntington disease, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Prion disease, Proteasome, Spinocerebellar ataxia 💬3件: 16, 28, 51 💬
102 Ixekizumab 💬1件: Ixekizumab1件: Ixekizumab1件: IL17A 💬 6件: Alcoholic liver disease, Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation 💬8件: 36, 37, 46, 107, 160, 162, 269, 271 💬