Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Obatoclax mesylate 💬1件: Obatoclax1件: Obatoclax1件: BCL2 💬 40件: AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Amyotrophic lateral sclerosis, Apoptosis, Apoptosis - multiple species, Autophagy - animal, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Colorectal cancer, Epstein-Barr virus infection, Estrogen signaling pathway, Fluid shear stress and atherosclerosis, Focal adhesion, Gastric cancer, HIF-1 signaling pathway, Hedgehog signaling pathway, Hepatitis B, Herpes simplex virus 1 infection, Human immunodeficiency virus 1 infection, JAK-STAT signaling pathway, Lipid and atherosclerosis, Measles, MicroRNAs in cancer, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Necroptosis, Neurotrophin signaling pathway, PI3K-Akt signaling pathway, Parathyroid hormone synthesis, secretion and action, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Prostate cancer, Protein processing in endoplasmic reticulum, Salmonella infection, Shigellosis, Small cell lung cancer, Sphingolipid signaling pathway, Toxoplasmosis, Tuberculosis, p53 signaling pathway 💬1件: 60 💬
2 Obecabtagene autoleucel 💬1件: Obecabtagene autoleucel2件: OBE-CEL; Obecabtagene autoleucel1件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬1件: 49 💬
3 Obeticholic acid 💬1件: Obeticholic acid2件: 6-ecdca; Obeticholic acid1件: NR1H4 💬 1件: Bile secretion 💬3件: 93, 265, 296 💬
4 Obexelimab 💬1件: Obexelimab2件: Obexelimab; XMAB58711件: CD19 💬 5件: B cell receptor signaling pathway, Epstein-Barr virus infection, Hematopoietic cell lineage, PI3K-Akt signaling pathway, Primary immunodeficiency 💬4件: 13, 49, 61, 300 💬
5 Obinutuzumab 💬1件: Obinutuzumab1件: Obinutuzumab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬5件: 43, 44, 49, 63, 222 💬
6 Ocrelizumab 💬1件: Ocrelizumab2件: Ocrelizumab; Rhumab 2h71件: MS4A1 💬 1件: Hematopoietic cell lineage 💬4件: 11, 13, 46, 49 💬
7 Octocog alfa 💬1件: Antihemophilic factor, human recombinant2件: Octocog alfa; Rahf1件: F8 💬 1件: Complement and coagulation cascades 💬1件: 288 💬
8 Octreotide 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
9 Octreotide acetate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
10 Octreotide acetate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
11 Octreotide pamoate 💬1件: Octreotide3件: Octreotida; Octreotide; Octreotide acetate1件: SSTR2 💬 5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬8件: 67, 75, 77, 84, 85, 89, 193, 227 💬
12 Odevixibat 💬1件: Odevixibat1件: Odevixibat1件: SLC10A2 💬 1件: Bile secretion 💬3件: 296, 297, 338 💬
13 Ofatumumab 💬1件: Ofatumumab2件: Humax-CD20; Ofatumumab1件: MS4A1 💬 1件: Hematopoietic cell lineage 💬4件: 11, 13, 35, 46 💬
14 Olanzapine 💬1件: Olanzapine1件: Olanzapine11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2,
HTR2,
HTR2,
HTR6 💬 		18件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8 💬
15 Olanzapine pamoate 💬1件: Olanzapine1件: Olanzapine11件: ADRA1A,
ADRA1B,
ADRA1D,
DRD2,
DRD3,
DRD4,
HRH1,
HTR2,
HTR2,
HTR2,
HTR6 💬 		18件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Alcoholism, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Hormone signaling, Inflammatory mediator regulation of TRP channels, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, Salivary secretion, Serotonergic synapse, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬2件: 2, 8 💬
16 Olaparib 💬1件: Olaparib1件: Olaparib2件: PARP1,
PARP2 💬 		5件: Apoptosis, Base excision repair, Diabetic cardiomyopathy, NF-kappa B signaling pathway, Necroptosis 💬2件: 86, 285 💬
17 Oleic acid 💬1件: Oleic Acid0件: ---
18 Olesoxime 💬1件: Olesoxime1件: Olesoxime--3件: 2, 3, 13 💬
19 Olipudase alfa 💬1件: Olipudase alfa1件: Olipudase alfa1件: SMPD1 💬 4件: Lysosome, Necroptosis, Sphingolipid metabolism, Sphingolipid signaling pathway 💬1件: 19 💬
20 Olive oil 💬1件: Olive oil1件: Olive OIL--3件: 34, 49, 53 💬
21 Olokizumab 💬1件: Olokizumab1件: Olokizumab1件: IL6 💬 49件: AGE-RAGE signaling pathway in diabetic complications, African trypanosomiasis, Alcoholic liver disease, Alzheimer disease, Amoebiasis, C-type lectin receptor signaling pathway, Cellular senescence, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Cytosolic DNA-sensing pathway, Epstein-Barr virus infection, FoxO signaling pathway, Graft-versus-host disease, HIF-1 signaling pathway, Hematopoietic cell lineage, Hepatitis B, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Intestinal immune network for IgA production, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Legionellosis, Lipid and atherosclerosis, Malaria, Measles, NOD-like receptor signaling pathway, Non-alcoholic fatty liver disease, PI3K-Akt signaling pathway, Pathogenic Escherichia coli infection, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Rheumatoid arthritis, Salmonella infection, TNF signaling pathway, Th17 cell differentiation, Toll-like receptor signaling pathway, Transcriptional misregulation in cancer, Tuberculosis, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection 💬2件: 46, 96 💬
22 Olsalazine 💬1件: Olsalazine1件: Olsalazine--1件: 271 💬
23 Olsalazine sodium 💬1件: Olsalazine1件: Olsalazine--1件: 271 💬
24 Omadacycline 💬1件: Omadacycline1件: Omadacycline--1件: 299 💬
25 Omadacycline tosylate 💬1件: Omadacycline1件: Omadacycline--1件: 299 💬
26 Omalizumab 💬1件: Omalizumab1件: Omalizumab1件: FCER1A 💬 4件: Asthma, Fc epsilon RI signaling pathway, Phospholipase D signaling pathway, Sphingolipid signaling pathway 💬7件: 46, 53, 65, 98, 162, 226, 299 💬
27 Omaveloxolone 💬1件: Omaveloxolone1件: Omaveloxolone1件: NFE2L2 💬 7件: Chemical carcinogenesis - reactive oxygen species, Fluid shear stress and atherosclerosis, Hepatocellular carcinoma, Lipid and atherosclerosis, Parkinson disease, Pathways in cancer, Protein processing in endoplasmic reticulum 💬1件: 18 💬
28 Omeprazole 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
29 Omeprazole magnesium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
30 Omeprazole sodium 💬1件: Omeprazole3件: Omeprazol; Omeprazole; Omeprazole magnesium2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬14件: 6, 13, 21, 46, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298 💬
31 Omidubicel 💬1件: Omidubicel1件: Omidubicel1件: CD34 💬 2件: Cell adhesion molecules, Hematopoietic cell lineage 💬1件: 60 💬
32 Onasemnogene abeparvovec 💬1件: Onasemnogene abeparvovec1件: Onasemnogene abeparvovec--1件: 3 💬
33 Ondansetron 💬1件: Ondansetron2件: Ondansetron; Ondansetron hydrochloride dihydrate5件: HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 97, 98, 107, 231 💬
34 Ondansetron hydrochloride hydrate 💬1件: Ondansetron2件: Ondansetron; Ondansetron hydrochloride dihydrate5件: HTR3,
HTR3,
HTR3,
HTR3,
HTR3 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Taste transduction 💬5件: 6, 97, 98, 107, 231 💬
35 Opicapone 💬1件: Opicapone1件: Opicapone1件: COMT 💬 3件: Dopaminergic synapse, Steroid hormone biosynthesis, Tyrosine metabolism 💬1件: 6 💬
36 Opicinumab 💬1件: Opicinumab1件: Opicinumab--1件: 13 💬
37 Oprelvekin 💬1件: Oprelvekin2件: Interleukin-11; Recombinant interleukin-111件: IL11RA 💬 3件: Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, JAK-STAT signaling pathway 💬3件: 96, 97, 288 💬
38 Orelabrutinib 💬1件: Orelabrutinib1件: Orelabrutinib1件: BTK 💬 7件: B cell receptor signaling pathway, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, Primary immunodeficiency 💬4件: 13, 49, 61, 63 💬
39 Orilanolimab 💬1件: Orilanolimab1件: Orilanolimab--1件: 61 💬
40 Ornithine 💬1件: Ornithine0件: ---
41 Ornithine aspartate 💬1件: Ornithine0件: ---
42 Orvepitant 💬1件: Orvepitant1件: Orvepitant1件: TACR1 💬 3件: Calcium signaling pathway, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction 💬1件: 85 💬
43 Oseltamivir 💬1件: Oseltamivir1件: Oseltamivir--2件: 97, 299 💬
44 Oseltamivir phosphate 💬1件: Oseltamivir1件: Oseltamivir--2件: 97, 299 💬
45 Osilodrostat 💬1件: Osilodrostat1件: Osilodrostat1件: CYP11B2 💬 2件: Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬1件: 75 💬
46 Osilodrostat phosphate 💬1件: Osilodrostat1件: Osilodrostat1件: CYP11B2 💬 2件: Aldosterone synthesis and secretion, Steroid hormone biosynthesis 💬1件: 75 💬
47 Otelixizumab 💬1件: Otelixizumab1件: Otelixizumab3件: CD3D,
CD3E,
CD3G 💬 		11件: Chagas disease, Epstein-Barr virus infection, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, Human immunodeficiency virus 1 infection, Measles, PD-L1 expression and PD-1 checkpoint pathway in cancer, Primary immunodeficiency, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation 💬1件: 46 💬
48 Otilimab 💬1件: Otilimab1件: Otilimab1件: CSF2 💬 16件: Acute myeloid leukemia, Amoebiasis, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Fc epsilon RI signaling pathway, Hematopoietic cell lineage, Human T-cell leukemia virus 1 infection, IL-17 signaling pathway, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Natural killer cell mediated cytotoxicity, Rheumatoid arthritis, Shigellosis, T cell receptor signaling pathway, TNF signaling pathway, Transcriptional misregulation in cancer 💬1件: 46 💬
49 Oxandrolone 💬1件: Oxandrolone1件: Oxandrolone1件: AR 💬 4件: Chemical carcinogenesis - receptor activation, Oocyte meiosis, Pathways in cancer, Prostate cancer 💬2件: 211, 285 💬
50 Oxatomide 💬1件: Oxatomide1件: Oxatomide1件: ALOX5 💬 6件: Arachidonic acid metabolism, Efferocytosis, Fc epsilon RI signaling pathway, Ovarian steroidogenesis, Serotonergic synapse, Toxoplasmosis 💬1件: 113 💬
51 Oxcarbazepine 💬1件: Oxcarbazepine1件: Oxcarbazepine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 13 💬
52 Oxiconazole 💬1件: Oxiconazole1件: Oxiconazole--1件: 160 💬
53 Oxiconazole nitrate 💬1件: Oxiconazole1件: Oxiconazole--1件: 160 💬
54 Oxiglutatione 💬1件: Glutathione1件: Glutathione--2件: 6, 299 💬
55 Oxitriptan 💬1件: Oxitriptan1件: Oxitriptan--1件: 97 💬
56 Oxybuprocaine 💬1件: Oxybuprocaine1件: Oxybuprocaine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬1件: 6 💬
57 Oxybutynin 💬1件: Oxybutynin0件: 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬-
58 Oxybutynin chloride 💬1件: Oxybutynin0件: 5件: CHRM1,
CHRM2,
CHRM3,
CHRM4,
CHRM5 💬 		14件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, PI3K-Akt signaling pathway, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction, cAMP signaling pathway 💬-
59 Oxycodone 💬1件: Oxycodone2件: Oxycodone; Oxycodone hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 46, 70, 226, 298 💬
60 Oxycodone hydrochloride 💬1件: Oxycodone2件: Oxycodone; Oxycodone hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 46, 70, 226, 298 💬
61 Oxycodone terephthalate 💬1件: Oxycodone2件: Oxycodone; Oxycodone hydrochloride3件: OPRD1,
OPRK1,
OPRM1 💬 		7件: Estrogen signaling pathway, Hormone signaling, Morphine addiction, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway, cGMP-PKG signaling pathway 💬5件: 6, 46, 70, 226, 298 💬
62 Oxygen 💬1件: Oxygen1件: Oxygen--13件: 22, 49, 70, 85, 86, 88, 149, 168, 235, 271, 298, 299, 330 💬
63 Oxyquinoline 💬1件: Oxyquinoline1件: Oxine--2件: 13, 51 💬
64 Oxyquinoline sulfate 💬1件: Oxyquinoline1件: Oxine--2件: 13, 51 💬
65 Oxytocin 💬1件: Oxytocin1件: Oxytocin1件: OXTR 💬 5件: Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Oxytocin signaling pathway, cAMP signaling pathway 💬4件: 127, 168, 193, 226 💬
66 Ozanezumab 💬1件: Ozanezumab1件: Ozanezumab1件: RTN4 💬 1件: Alzheimer disease 💬1件: 2 💬
67 Ozanimod 💬1件: Ozanimod2件: Ozanimod; Ozanimod hydrochloride5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		4件: Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 96, 97 💬
68 Ozanimod hydrochloride 💬1件: Ozanimod2件: Ozanimod; Ozanimod hydrochloride5件: S1PR1,
S1PR2,
S1PR3,
S1PR4,
S1PR5 💬 		4件: Efferocytosis, FoxO signaling pathway, Neuroactive ligand-receptor interaction, Sphingolipid signaling pathway 💬3件: 13, 96, 97 💬
69 Ozoralizumab 💬1件: Ozoralizumab1件: Ozoralizumab1件: TNF 💬 66件: AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, African trypanosomiasis, Alcoholic liver disease, Allograft rejection, Alzheimer disease, Amoebiasis, Amyotrophic lateral sclerosis, Antigen processing and presentation, Apoptosis, Asthma, C-type lectin receptor signaling pathway, Chagas disease, Coronavirus disease - COVID-19, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Epstein-Barr virus infection, Fc epsilon RI signaling pathway, Fluid shear stress and atherosclerosis, Graft-versus-host disease, Hematopoietic cell lineage, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Human papillomavirus infection, Hypertrophic cardiomyopathy, IL-17 signaling pathway, Inflammatory bowel disease, Influenza A, Insulin resistance, Legionellosis, Leishmaniasis, Lipid and atherosclerosis, MAPK signaling pathway, Malaria, NF-kappa B signaling pathway, NOD-like receptor signaling pathway, Natural killer cell mediated cytotoxicity, Necroptosis, Non-alcoholic fatty liver disease, Osteoclast differentiation, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Pertussis, Prion disease, Proteoglycans in cancer, RIG-I-like receptor signaling pathway, Rheumatoid arthritis, Salmonella infection, Shigellosis, Sphingolipid signaling pathway, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Toxoplasmosis, Tuberculosis, Type I diabetes mellitus, Type II diabetes mellitus, Viral protein interaction with cytokine and cytokine receptor, Yersinia infection, mTOR signaling pathway 💬1件: 46 💬