Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Betaine 💬1件: Betaine1件: Betaine--4件: 117, 201, 234, 337 💬
2 Betaine citrate 💬1件: Betaine1件: Betaine--4件: 117, 201, 234, 337 💬
3 Betaine hydrochloride 💬1件: Betaine1件: Betaine--4件: 117, 201, 234, 337 💬
4 Chenodiol 💬1件: Chenodeoxycholic acid2件: Chenodeoxycholic acid; Chenodiol1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 96, 234, 263 💬
5 Cholic acid 💬1件: Cholic Acid1件: Cholic acid1件: NR1H4 💬 1件: Bile secretion 💬4件: 20, 234, 265, 310 💬
6 Clofarabine 💬1件: Clofarabine1件: Clofarabine3件: POLA1,
POLA2,
RRM1 💬 		5件: DNA replication, Drug metabolism - other enzymes, Glutathione metabolism, Purine metabolism, Pyrimidine metabolism 💬5件: 19, 20, 60, 96, 234 💬
7 Cyclosporine 💬1件: Cyclosporine6件: Ciclosporin; Ciclosporina; Ciclosporine; Cyclosporin; Cyclosporin A; Cyclosporine5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬37件: 11, 26, 28, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 269, 274, 283, 284, 285, 302, 326 💬
8 Esomeprazole 💬1件: Esomeprazole3件: Esomeprazole; Esomeprazole magnesium; Omeprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
9 Esomeprazole magnesium 💬1件: Esomeprazole3件: Esomeprazole; Esomeprazole magnesium; Omeprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
10 Esomeprazole magnesium dihydrate 💬1件: Esomeprazole3件: Esomeprazole; Esomeprazole magnesium; Omeprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
11 Esomeprazole sodium 💬1件: Esomeprazole3件: Esomeprazole; Esomeprazole magnesium; Omeprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
12 Esomeprazole strontium 💬1件: Esomeprazole3件: Esomeprazole; Esomeprazole magnesium; Omeprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬10件: 6, 13, 46, 86, 98, 107, 113, 234, 298, 299 💬
13 Hydroxychloroquine 💬1件: Hydroxychloroquine2件: Hydroxychloroquine; Hydroxychloroquine sulfate--26件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
14 Hydroxychloroquine sulfate 💬1件: Hydroxychloroquine2件: Hydroxychloroquine; Hydroxychloroquine sulfate--26件: 6, 13, 34, 41, 43, 44, 45, 46, 48, 49, 53, 56, 63, 66, 84, 96, 97, 107, 218, 222, 224, 234, 254, 271, 298, 299 💬
15 Lumasiran 💬1件: Lumasiran1件: Lumasiran1件: HAO 💬 2件: Glyoxylate and dicarboxylate metabolism, Peroxisome 💬1件: 234 💬
16 Lumasiran sodium 💬1件: Lumasiran1件: Lumasiran1件: HAO 💬 2件: Glyoxylate and dicarboxylate metabolism, Peroxisome 💬1件: 234 💬
17 Melphalan 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
18 Melphalan hydrochloride 💬1件: Melphalan2件: Melphalan; Melphalan hydrochloride--19件: 11, 13, 14, 19, 20, 28, 34, 46, 60, 62, 65, 96, 107, 164, 222, 234, 284, 285, 299 💬
19 Mycophenolate mofetil 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
20 Mycophenolate mofetil hydrochloride 💬1件: Mycophenolate mofetil1件: Mycophenolate mofetil2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬32件: 2, 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 46, 49, 51, 53, 60, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
21 Mycophenolate sodium 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
22 Mycophenolic acid 💬1件: Mycophenolic acid5件: Acido micofenolico; Micofenolico acido; Mycophenolate; Mycophenolate sodium; Mycophenolic acid2件: IMPDH,
IMPDH 💬 		2件: Drug metabolism - other enzymes, Purine metabolism 💬12件: 11, 43, 49, 51, 53, 60, 66, 84, 96, 162, 222, 228 💬
23 Nedosiran sodium 💬1件: Nedosiran1件: Nedosiran1件: LDH 💬 7件: Central carbon metabolism in cancer, Cysteine and methionine metabolism, Glucagon signaling pathway, Glycolysis / Gluconeogenesis, HIF-1 signaling pathway, Propanoate metabolism, Pyruvate metabolism 💬1件: 234 💬
24 Pyridoxine 💬1件: Pyridoxine1件: Pyridoxine--1件: 320 💬
25 Pyridoxine hydrochloride 💬1件: Pyridoxine1件: Pyridoxine--1件: 320 💬
26 Stiripentol 💬1件: Stiripentol1件: Stiripentol--2件: 140, 234 💬
27 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
28 Tacrolimus 💬1件: Tacrolimus1件: Tacrolimus5件: PPP3C,
PPP3C,
PPP3C,
PPP3R,
PPP3R 💬 		33件: Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Axon guidance, B cell receptor signaling pathway, C-type lectin receptor signaling pathway, Calcium signaling pathway, Cellular senescence, Dopaminergic synapse, Glucagon signaling pathway, Glutamatergic synapse, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human immunodeficiency virus 1 infection, Kaposi sarcoma-associated herpesvirus infection, Lipid and atherosclerosis, Long-term potentiation, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Oocyte meiosis, Osteoclast differentiation, Oxytocin signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, T cell receptor signaling pathway, Th1 and Th2 cell differentiation, Th17 cell differentiation, Tuberculosis, VEGF signaling pathway, Wnt signaling pathway, cGMP-PKG signaling pathway 💬31件: 2, 6, 11, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286 💬
29 Ursodiol 💬1件: Ursodeoxycholic acid3件: Udca; Ursodeoxycholic acid; Ursodiol1件: NR1H4 💬 1件: Bile secretion 💬13件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 296, 299 💬