Drug Description in Trials / DrugBank / KEGG DRUG

  

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No. KEGG DRUG DrugBank 薬物名（臨床試験情報から抽出） KEGG GENES KEGG PATHWAY 指定難病告示番号
1 Diclofenac sodium 💬
(DICLOFENAC SODIUM DELAYED RELEASE)		1件: Diclofenac2件: Diclofenac; Diclofenac sodium2件: PTGS1,
PTGS2 💬 		23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬3件: 34, 46, 271 💬
2 Diltiazem hydrochloride 💬
(DILTIAZEM HYDROCHLORIDE EXTENDED RELEASE, DILTIAZEM HYDROCHLORIDE EXTENDED-RELEASE)		1件: Diltiazem2件: Diltiazem; Diltiazem hydrochloride4件: CACNA1C,
CACNA1D,
CACNA1F,
CACNA1S 💬 		37件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Alzheimer disease, Amphetamine addiction, Arrhythmogenic right ventricular cardiomyopathy, Calcium signaling pathway, Carbohydrate digestion and absorption, Cardiac muscle contraction, Cellular senescence, Chemical carcinogenesis - receptor activation, Cholinergic synapse, Circadian entrainment, Cortisol synthesis and secretion, Cushing syndrome, Dilated cardiomyopathy, Dopaminergic synapse, GABAergic synapse, Glutamatergic synapse, GnRH secretion, GnRH signaling pathway, Growth hormone synthesis, secretion and action, Hypertrophic cardiomyopathy, Insulin secretion, Long-term potentiation, MAPK signaling pathway, Oxytocin signaling pathway, Pathways of neurodegeneration - multiple diseases, Prion disease, Renin secretion, Retrograde endocannabinoid signaling, Serotonergic synapse, Taste transduction, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway 💬4件: 51, 58, 86, 88 💬
3 Guanfacine hydrochloride 💬
(GUANFACINE EXTENDED-RELEASE)		1件: Guanfacine0件: 1件: ADRA2A 💬 4件: Hormone signaling, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, cGMP-PKG signaling pathway 💬-
4 Lamotrigine 💬
(LAMOTRIGINE EXTENDED RELEASE)		1件: Lamotrigine1件: Lamotrigine5件: SCN1A,
SCN2A,
SCN3A,
SCN5A,
SCN9A 💬 		3件: Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction 💬5件: 13, 34, 113, 114, 144 💬
5 Metformin hydrochloride 💬
(METFORMIN HYDROCHLORIDE EXTENDED RELEASE, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE, METFORMIN HYDROCHLORIDE EXTENDED-RELEASE 500MG)		1件: Metformin3件: Metformin; Metformin hydrochloride; Metformina2件: PRKAA,
PRKAA 💬 		20件: AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬27件: 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 75, 77, 81, 84, 86, 97, 113, 127, 158, 206, 218, 225, 265, 285, 298, 299, 301 💬
6 Methylphenidate hydrochloride 💬
(METHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASE)		1件: Methylphenidate2件: Methylphenidate; Methylphenidate hydrochloride2件: SLC6A2,
SLC6A3 💬 		8件: Alcoholism, Amphetamine addiction, Cocaine addiction, Dopaminergic synapse, Neuroactive ligand signaling, Parkinson disease, Pathways of neurodegeneration - multiple diseases, Synaptic vesicle cycle 💬5件: 6, 13, 34, 84, 113 💬
7 Pantoprazole sodium 💬
(PANTOPRAZOLE SODIUM DELAYED-RELEASE)		1件: Pantoprazole1件: Pantoprazole2件: ATP4A,
ATP4B 💬 		3件: Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬2件: 13, 65 💬
8 Potassium chloride 💬
(POTASSIUM CHLORIDE EXTENDED RELEASE, POTASSIUM CHLORIDE EXTENDED-RELEASE)		1件: Potassium chloride1件: Potassium chloride--1件: 97 💬
9 Pregabalin 💬
(PREGABALIN EXTENDED RELEASE)		1件: Pregabalin1件: Pregabalin4件: CACNA2D1,
CACNA2D2,
CACNA2D3,
CACNA2D4 💬 		7件: Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway 💬5件: 13, 36, 46, 70, 298 💬
10 Somatostatin 💬1件: Somatostatin (Synthetic growth hormone release-inhibiting hormone)1件: Somatostatin5件: SSTR1,
SSTR2,
SSTR3,
SSTR4,
SSTR5 💬 		5件: Gastric acid secretion, Growth hormone synthesis, secretion and action, Hormone signaling, Neuroactive ligand-receptor interaction, cAMP signaling pathway 💬1件: 77 💬
11 Tolterodine tartrate 💬
(TOLTERODINE TARTRATE EXTENDED RELEASE)		1件: Tolterodine1件: Tolterodine1件: CHRM3 💬 12件: Alzheimer disease, Calcium signaling pathway, Cholinergic synapse, Gastric acid secretion, Insulin secretion, Neuroactive ligand signaling, Neuroactive ligand-receptor interaction, Pancreatic secretion, Pathways of neurodegeneration - multiple diseases, Regulation of actin cytoskeleton, Salivary secretion, Taste transduction 💬1件: 17 💬
12 Venlafaxine hydrochloride 💬
(VENLAFAXINE HYDROCHLORIDE, EXTENDED RELEASE)		1件: Venlafaxine2件: Venlafaxine; Venlafaxine hydrochloride2件: SLC6A2,
SLC6A4 💬 		3件: Neuroactive ligand signaling, Serotonergic synapse, Synaptic vesicle cycle 💬4件: 6, 13, 46, 97 💬