Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alcoholic liver disease 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
2 Alcoholic liver disease 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
3 Calcium signaling pathway 💬
1件: HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
4 Calcium signaling pathway 💬
1件: HRH1 💬 Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
5 Complement and coagulation cascades 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
6 Complement and coagulation cascades 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
7 Complement and coagulation cascades 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
8 Coronavirus disease - COVID-19 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
9 Coronavirus disease - COVID-19 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
10 Coronavirus disease - COVID-19 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
11 Cortisol synthesis and secretion 💬
1件: KCNA4 💬 Dalfampridine 💬 Dalfampridine 4件:  3 ,  4 , 13, 14 💬
12 Cushing syndrome 💬
1件: KCNA4 💬 Dalfampridine 💬 Dalfampridine 4件:  3 ,  4 , 13, 14 💬
13 Efferocytosis 💬
1件: S1PR1 💬 Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
14 Efferocytosis 💬
1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
15 Efferocytosis 💬
1件: S1PR1 💬 Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
16 FoxO signaling pathway 💬
1件: S1PR1 💬 Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
17 FoxO signaling pathway 💬
1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
18 FoxO signaling pathway 💬
1件: S1PR1 💬 Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
19 Hematopoietic cell lineage 💬
1件: MS4A1 💬 Rituximab 💬 Rituximab 52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
20 Herpes simplex virus 1 infection 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
21 Inflammatory mediator regulation of TRP channels 💬
1件: HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
22 Inflammatory mediator regulation of TRP channels 💬
1件: HRH1 💬 Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
23 Neuroactive ligand signaling 💬
1件: HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
24 Neuroactive ligand signaling 💬
1件: HRH1 💬 Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
25 Neuroactive ligand-receptor interaction 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
26 Neuroactive ligand-receptor interaction 💬
1件: HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
27 Neuroactive ligand-receptor interaction 💬
1件: HRH1 💬 Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
28 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Dexamethasone 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
29 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Dexamethasone sodium phosphate 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
30 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Dexamethasone phosphate 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
31 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Methylprednisolone 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
32 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Methylprednisolone acetate 💬 Methylprednisolone 48件:  2 ,  6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
33 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Prednisolone 💬 Prednisolone 41件:  3 , 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
34 Neuroactive ligand-receptor interaction 💬
1件: NR3C1 💬 Prednisone 💬 Prednisone 54件:  2 , 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
35 Neuroactive ligand-receptor interaction 💬
1件: S1PR1 💬 Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
36 Neuroactive ligand-receptor interaction 💬
1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
37 Neuroactive ligand-receptor interaction 💬
1件: S1PR1 💬 Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
38 Neutrophil extracellular trap formation 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
39 Pertussis 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
40 Pertussis 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
41 Pertussis 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
42 Prion disease 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
43 Regulation of actin cytoskeleton 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
44 Serotonergic synapse 💬
1件: KCND2 💬 Dalfampridine 💬 Dalfampridine 4件:  3 ,  4 , 13, 14 💬
45 Sphingolipid signaling pathway 💬
1件: S1PR1 💬 Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
46 Sphingolipid signaling pathway 💬
1件: S1PR1 💬 Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬
47 Sphingolipid signaling pathway 💬
1件: S1PR1 💬 Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
48 Spinocerebellar ataxia 💬
2件: KCNC3, KCND3 💬 Dalfampridine 💬 Dalfampridine 4件:  3 ,  4 , 13, 14 💬
49 Staphylococcus aureus infection 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
50 Staphylococcus aureus infection 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
51 Staphylococcus aureus infection 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
52 Systemic lupus erythematosus 💬
1件: C1S 💬 Riliprubart 💬 Riliprubart 1件: 14 💬
53 Systemic lupus erythematosus 💬
1件: C2 💬 Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
54 Systemic lupus erythematosus 💬
1件: C5 💬 Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬