Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 C1S 💬 5件: Complement and coagulation cascades, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Riliprubart 💬 Riliprubart 1件: 14 💬
2 C2 💬 6件: Complement and coagulation cascades, Alcoholic liver disease, Pertussis, Staphylococcus aureus infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Empasiprubart 💬 Empasiprubart 2件: 14, 50 💬
3 C5 💬 11件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Neutrophil extracellular trap formation, Regulation of actin cytoskeleton, Alcoholic liver disease, Prion disease, Pertussis, Staphylococcus aureus infection, Herpes simplex virus 1 infection, Coronavirus disease - COVID-19, Systemic lupus erythematosus Eculizumab 💬 Eculizumab 8件: 11, 13, 14, 61, 62, 109, 221, 222 💬
4 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
5 HRH1 💬 4件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Neuroactive ligand signaling, Inflammatory mediator regulation of TRP channels Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
6 KCNA4 💬 2件: Cortisol synthesis and secretion, Cushing syndrome Dalfampridine 💬 Dalfampridine 4件: 3, 4, 13, 14 💬
7 KCNC3 💬 1件: Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine 4件: 3, 4, 13, 14 💬
8 KCND2 💬 1件: Serotonergic synapse Dalfampridine 💬 Dalfampridine 4件: 3, 4, 13, 14 💬
9 KCND3 💬 1件: Spinocerebellar ataxia Dalfampridine 💬 Dalfampridine 4件: 3, 4, 13, 14 💬
10 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
11 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisolone 💬 Prednisolone 41件: 3, 11, 13, 14, 18, 25, 26, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 54, 56, 60, 61, 63, 64, 66, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 251, 269, 271, 296, 299, 300 💬
12 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone sodium phosphate 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
13 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone phosphate 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
14 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Dexamethasone 💬 Dexamethasone 25件: 13, 14, 16, 19, 28, 35, 53, 63, 64, 65, 70, 74, 75, 81, 84, 90, 96, 97, 162, 222, 235, 257, 296, 299, 331 💬
15 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
16 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone 💬 Methylprednisolone 48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
17 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Methylprednisolone acetate 💬 Methylprednisolone 48件: 2, 6, 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 95, 96, 97, 127, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296, 300 💬
18 S1PR1 💬 4件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Fingolimod hydrochloride 💬 Fingolimod 3件: 13, 14, 156 💬
19 S1PR1 💬 4件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Fingolimod lauryl sulfate 💬 Fingolimod 3件: 13, 14, 156 💬
20 S1PR1 💬 4件: FoxO signaling pathway, Sphingolipid signaling pathway, Neuroactive ligand-receptor interaction, Efferocytosis Fingolimod 💬 Fingolimod 3件: 13, 14, 156 💬