Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Acute myeloid leukemia 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
2 Autoimmune thyroid disease 💬
1件: CTLA4 💬 Ipilimumab 💬 Ipilimumab 1件: 159 💬
3 Cell adhesion molecules 💬
1件: CTLA4 💬 Ipilimumab 💬 Ipilimumab 1件: 159 💬
4 Cell adhesion molecules 💬
1件: PDCD1 💬 Nivolumab 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
5 Estrogen signaling pathway 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
6 Gastric cancer 💬
1件: RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
7 Hormone signaling 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
8 Hormone signaling 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
9 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
10 Melanogenesis 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
11 Neuroactive ligand-receptor interaction 💬
1件: MC1R 💬 Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
12 Neuroactive ligand-receptor interaction 💬
1件: MC1R 💬 Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
13 Non-small cell lung cancer 💬
1件: RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
14 Pathways in cancer 💬
2件: RARA, RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
15 PD-L1 expression and PD-1 checkpoint pathway in cancer 💬
1件: PDCD1 💬 Nivolumab 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
16 Rheumatoid arthritis 💬
1件: CTLA4 💬 Ipilimumab 💬 Ipilimumab 1件: 159 💬
17 Small cell lung cancer 💬
1件: RARB 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
18 T cell receptor signaling pathway 💬
1件: CTLA4 💬 Ipilimumab 💬 Ipilimumab 1件: 159 💬
19 T cell receptor signaling pathway 💬
1件: PDCD1 💬 Nivolumab 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
20 Th17 cell differentiation 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
21 Transcriptional misregulation in cancer 💬
1件: RARA 💬 Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬