Target Gene/Pathway Pathway / Gene

  

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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CTLA4 💬 4件: Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, Autoimmune thyroid disease, Rheumatoid arthritis Ipilimumab 💬 Ipilimumab 9件: 13, 46, 49, 50, 51, 53, 96, 97, 159 💬
2 MC1R 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Melanogenesis Afamelanotide acetate 💬 Afamelanotide 2件: 159, 254 💬
3 MC1R 💬 3件: Neuroactive ligand-receptor interaction, Hormone signaling, Melanogenesis Afamelanotide 💬 Afamelanotide 2件: 159, 254 💬
4 MTNR1A 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
5 MTNR1B 💬 2件: Neuroactive ligand-receptor interaction, Circadian entrainment Melatonin 💬 Melatonin 18件: 2, 6, 8, 13, 37, 46, 49, 72, 78, 86, 90, 96, 97, 145, 149, 159, 202, 265 💬
6 PDCD1 💬 3件: Cell adhesion molecule (CAM) interaction, T cell receptor signaling pathway, PD-L1 expression and PD-1 checkpoint pathway in cancer Nivolumab 💬 Nivolumab 12件: 13, 26, 41, 46, 49, 50, 51, 53, 85, 96, 97, 159 💬
7 RARA 💬 5件: Th17 cell differentiation, Estrogen signaling pathway, Pathways in cancer, Transcriptional misregulation in cancer, Acute myeloid leukemia Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬
8 RARB 💬 4件: Pathways in cancer, Small cell lung cancer, Non-small cell lung cancer, Gastric cancer Isotretinoin 💬 Isotretinoin 4件: 36, 39, 159, 160 💬