Target Gene/Pathway Pathway / Gene
Search results
| No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related | KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 1 | Alanine, aspartate and glutamate metabolism 💬 5 genes, 3 drugs (DrugBank) and 18 diseases |
CPS1 1件: CPS1 💬Alanine, aspartate and glutamate metabolism
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Carglumic acid Carglumic acid 💬Alanine, aspartate and glutamate metabolism
| Carglumic acid | 245 3件: 245, 246, 251 💬
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| 2 | Aldosterone synthesis and secretion 💬 20 genes, 41 drugs (DrugBank) and 61 diseases |
PDE2A 1件: PDE2A 💬Aldosterone synthesis and secretion
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Bucladesine Bucladesine 💬Aldosterone synthesis and secretion
| Bucladesine | 246 1件: 246 💬2. Aldosterone synthesis and secretion
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| 3 | Apelin signaling pathway 💬 20 genes, 36 drugs (DrugBank) and 77 diseases |
PDE3B 1件: PDE3B 💬Apelin signaling pathway
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Bucladesine Bucladesine 💬Apelin signaling pathway
| Bucladesine | 246 1件: 246 💬3. Apelin signaling pathway
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| 4 | Arginine biosynthesis 💬 4 genes, 2 drugs (DrugBank) and 4 diseases |
CPS1 1件: CPS1 💬Arginine biosynthesis
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Carglumic acid Carglumic acid 💬Arginine biosynthesis
| Carglumic acid | 245 3件: 245, 246, 251 💬
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| 5 | Calcium signaling pathway 💬 86 genes, 214 drugs (DrugBank) and 143 diseases |
PDE1 3件: PDE1, PDE1, PDE1 💬
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Bucladesine Bucladesine 💬Calcium signaling pathway
| Bucladesine | 246 1件: 246 💬5. Calcium signaling pathway
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| 6 | cAMP signaling pathway 💬 66 genes, 189 drugs (DrugBank) and 130 diseases |
PDE10 7件: PDE10, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4 💬
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Bucladesine Bucladesine 💬cAMP signaling pathway
| Bucladesine | 246 1件: 246 💬6. cAMP signaling pathway
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| 7 | cGMP-PKG signaling pathway 💬 49 genes, 132 drugs (DrugBank) and 124 diseases |
PDE2A 3件: PDE2A, PDE3A, PDE3B 💬
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Bucladesine Bucladesine 💬cGMP-PKG signaling pathway
| Bucladesine | 246 1件: 246 💬7. cGMP-PKG signaling pathway
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| 8 | Cortisol synthesis and secretion 💬 15 genes, 36 drugs (DrugBank) and 63 diseases |
PDE8 2件: PDE8, PDE8 💬
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Bucladesine Bucladesine 💬Cortisol synthesis and secretion
| Bucladesine | 246 1件: 246 💬8. Cortisol synthesis and secretion
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| 9 | Cushing syndrome 💬 24 genes, 55 drugs (DrugBank) and 71 diseases |
PDE11 3件: PDE11, PDE8, PDE8 💬
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Bucladesine Bucladesine 💬Cushing syndrome
| Bucladesine | 246 1件: 246 💬9. Cushing syndrome
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| 10 | Cytokine-cytokine receptor interaction 💬 89 genes, 142 drugs (DrugBank) and 110 diseases |
GHR 1件: GHR 💬Cytokine-cytokine receptor interaction
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Somatropin Somatropin 💬Cytokine-cytokine receptor interaction
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬10. Cytokine-cytokine receptor interaction
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| 11 | Glucagon signaling pathway 💬 14 genes, 23 drugs (DrugBank) and 82 diseases |
PDE3B 1件: PDE3B 💬Glucagon signaling pathway
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Bucladesine Bucladesine 💬Glucagon signaling pathway
| Bucladesine | 246 1件: 246 💬11. Glucagon signaling pathway
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| 12 | Growth hormone synthesis, secretion and action 💬 23 genes, 49 drugs (DrugBank) and 100 diseases |
GHR 1件: GHR 💬Growth hormone synthesis, secretion and action
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Somatropin Somatropin 💬Growth hormone synthesis, secretion and action
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬12. Growth hormone synthesis, secretion and action
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| 13 | Hormone signaling 💬 66 genes, 211 drugs (DrugBank) and 153 diseases |
GHR 1件: GHR 💬Hormone signaling
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Somatropin Somatropin 💬Hormone signaling
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬13. Hormone signaling
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| 14 | Insulin signaling pathway 💬 12 genes, 28 drugs (DrugBank) and 71 diseases |
PDE3B 1件: PDE3B 💬Insulin signaling pathway
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Bucladesine Bucladesine 💬Insulin signaling pathway
| Bucladesine | 246 1件: 246 💬14. Insulin signaling pathway
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| 15 | JAK-STAT signaling pathway 💬 61 genes, 113 drugs (DrugBank) and 123 diseases |
GHR 1件: GHR 💬JAK-STAT signaling pathway
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Somatropin Somatropin 💬JAK-STAT signaling pathway
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬15. JAK-STAT signaling pathway
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| 16 | Morphine addiction 💬 41 genes, 69 drugs (DrugBank) and 76 diseases |
PDE1 16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬
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Bucladesine Bucladesine 💬Morphine addiction
| Bucladesine | 246 1件: 246 💬16. Morphine addiction
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| 17 | Neuroactive ligand-receptor interaction 💬 158 genes, 364 drugs (DrugBank) and 173 diseases |
GHR 1件: GHR 💬Neuroactive ligand-receptor interaction
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Somatropin Somatropin 💬Neuroactive ligand-receptor interaction
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬17. Neuroactive ligand-receptor interaction
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| 18 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 15 diseases |
CPS1 1件: CPS1 💬Nitrogen metabolism
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Carglumic acid Carglumic acid 💬Nitrogen metabolism
| Carglumic acid | 245 3件: 245, 246, 251 💬
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| 19 | Olfactory transduction 💬 4 genes, 5 drugs (DrugBank) and 13 diseases |
PDE1 4件: PDE1, PDE1, PDE1, PDE2A 💬
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Bucladesine Bucladesine 💬Olfactory transduction
| Bucladesine | 246 1件: 246 💬19. Olfactory transduction
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| 20 | Parathyroid hormone synthesis, secretion and action 💬 22 genes, 58 drugs (DrugBank) and 72 diseases |
PDE4 4件: PDE4, PDE4, PDE4, PDE4 💬
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Bucladesine Bucladesine 💬Parathyroid hormone synthesis, secretion and action
| Bucladesine | 246 1件: 246 💬20. Parathyroid hormone synthesis, secretion and action
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| 21 | PI3K-Akt signaling pathway 💬 85 genes, 142 drugs (DrugBank) and 131 diseases |
GHR 1件: GHR 💬PI3K-Akt signaling pathway
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Somatropin Somatropin 💬PI3K-Akt signaling pathway
| Somatotropin | 002 28件: 2 , 3 , 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬21. PI3K-Akt signaling pathway
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| 22 | Progesterone-mediated oocyte maturation 💬 14 genes, 38 drugs (DrugBank) and 46 diseases |
PDE3B 1件: PDE3B 💬Progesterone-mediated oocyte maturation
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Bucladesine Bucladesine 💬Progesterone-mediated oocyte maturation
| Bucladesine | 246 1件: 246 💬22. Progesterone-mediated oocyte maturation
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| 23 | Purine metabolism 💬 30 genes, 40 drugs (DrugBank) and 73 diseases |
PDE1 16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬
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Bucladesine Bucladesine 💬Purine metabolism
| Bucladesine | 246 1件: 246 💬23. Purine metabolism
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| 24 | Regulation of lipolysis in adipocytes 💬 13 genes, 71 drugs (DrugBank) and 79 diseases |
PDE3B 1件: PDE3B 💬Regulation of lipolysis in adipocytes
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Bucladesine Bucladesine 💬Regulation of lipolysis in adipocytes
| Bucladesine | 246 1件: 246 💬24. Regulation of lipolysis in adipocytes
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| 25 | Renin secretion 💬 28 genes, 87 drugs (DrugBank) and 113 diseases |
PDE1 5件: PDE1, PDE1, PDE1, PDE3A, PDE3B 💬
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Bucladesine Bucladesine 💬Renin secretion
| Bucladesine | 246 1件: 246 💬25. Renin secretion
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| 26 | Taste transduction 💬 28 genes, 91 drugs (DrugBank) and 68 diseases |
PDE1 3件: PDE1, PDE1, PDE1 💬
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Bucladesine Bucladesine 💬Taste transduction
| Bucladesine | 246 1件: 246 💬26. Taste transduction
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Alanine, aspartate and glutamate metabolism
5 genes, 3 drugs (DrugBank) and 18 diseases
Aldosterone synthesis and secretion
20 genes, 41 drugs (DrugBank) and 61 diseases
Apelin signaling pathway
20 genes, 36 drugs (DrugBank) and 77 diseases
Arginine biosynthesis
4 genes, 2 drugs (DrugBank) and 4 diseases
Calcium signaling pathway
86 genes, 214 drugs (DrugBank) and 143 diseases
cAMP signaling pathway
66 genes, 189 drugs (DrugBank) and 130 diseases
cGMP-PKG signaling pathway
49 genes, 132 drugs (DrugBank) and 124 diseases
Cortisol synthesis and secretion
15 genes, 36 drugs (DrugBank) and 63 diseases
Cushing syndrome
24 genes, 55 drugs (DrugBank) and 71 diseases
Cytokine-cytokine receptor interaction
89 genes, 142 drugs (DrugBank) and 110 diseases
Glucagon signaling pathway
14 genes, 23 drugs (DrugBank) and 82 diseases
Growth hormone synthesis, secretion and action
23 genes, 49 drugs (DrugBank) and 100 diseases
Hormone signaling
66 genes, 211 drugs (DrugBank) and 153 diseases
Insulin signaling pathway
12 genes, 28 drugs (DrugBank) and 71 diseases
JAK-STAT signaling pathway
61 genes, 113 drugs (DrugBank) and 123 diseases
Morphine addiction
41 genes, 69 drugs (DrugBank) and 76 diseases
Neuroactive ligand-receptor interaction
158 genes, 364 drugs (DrugBank) and 173 diseases
Nitrogen metabolism
14 genes, 5 drugs (DrugBank) and 15 diseases
Olfactory transduction
4 genes, 5 drugs (DrugBank) and 13 diseases
Parathyroid hormone synthesis, secretion and action
22 genes, 58 drugs (DrugBank) and 72 diseases
PI3K-Akt signaling pathway
85 genes, 142 drugs (DrugBank) and 131 diseases
Progesterone-mediated oocyte maturation
14 genes, 38 drugs (DrugBank) and 46 diseases
Purine metabolism
30 genes, 40 drugs (DrugBank) and 73 diseases
Regulation of lipolysis in adipocytes
13 genes, 71 drugs (DrugBank) and 79 diseases
Renin secretion
28 genes, 87 drugs (DrugBank) and 113 diseases
Taste transduction
28 genes, 91 drugs (DrugBank) and 68 diseases