Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 CPS1 💬 3件: Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism Carglumic acid 💬 Carglumic acid 3件: 245, 246, 251 💬
2 GHR 💬 6件: Cytokine-cytokine receptor interaction, Neuroactive ligand-receptor interaction, Hormone signaling, PI3K-Akt signaling pathway, JAK-STAT signaling pathway, Growth hormone synthesis, secretion and action Somatropin 💬 Somatotropin 28件: 2, 3, 13, 19, 36, 46, 65, 74, 75, 76, 77, 78, 96, 97, 107, 113, 156, 187, 191, 193, 195, 238, 246, 265, 274, 276, 299, 337 💬
3 PDE1 💬 6件: Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
4 PDE1 💬 6件: Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
5 PDE1 💬 6件: Purine metabolism, Calcium signaling pathway, Olfactory transduction, Taste transduction, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
6 PDE10 💬 3件: Purine metabolism, cAMP signaling pathway, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
7 PDE11 💬 3件: Purine metabolism, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
8 PDE2A 💬 5件: Purine metabolism, cGMP-PKG signaling pathway, Olfactory transduction, Aldosterone synthesis and secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
9 PDE3A 💬 5件: Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
10 PDE3B 💬 10件: Purine metabolism, cGMP-PKG signaling pathway, cAMP signaling pathway, Apelin signaling pathway, Insulin signaling pathway, Progesterone-mediated oocyte maturation, Glucagon signaling pathway, Regulation of lipolysis in adipocytes, Renin secretion, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
11 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
12 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
13 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
14 PDE4 💬 4件: Purine metabolism, cAMP signaling pathway, Parathyroid hormone synthesis, secretion and action, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
15 PDE7 💬 2件: Purine metabolism, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
16 PDE7 💬 2件: Purine metabolism, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
17 PDE8 💬 4件: Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬
18 PDE8 💬 4件: Purine metabolism, Cortisol synthesis and secretion, Cushing syndrome, Morphine addiction Bucladesine 💬 Bucladesine 1件: 246 💬