Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Alzheimer disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
2 AMPK signaling pathway 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
3 Amyotrophic lateral sclerosis 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
4 Bile secretion 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
5 Calcium signaling pathway 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
6 Complement and coagulation cascades 💬
 2件: F10, F9 💬 Emicizumab 💬 Emicizumab 1件: 288 💬
7 Complement and coagulation cascades 💬
 1件: F7 💬 Eptacog alfa 💬 Coagulation factor VIIa Recombinant Human 1件: 288 💬
8 Complement and coagulation cascades 💬
 1件: F8 💬 Octocog alfa 💬 Antihemophilic factor, human recombinant 1件: 288 💬
9 Complement and coagulation cascades 💬
 1件: F8 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
10 Complement and coagulation cascades 💬
 1件: F8 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
11 Complement and coagulation cascades 💬
 1件: F8 💬 Efanesoctocog alfa 💬 Efanesoctocog alfa 1件: 288 💬
12 Complement and coagulation cascades 💬
 1件: F8 💬 Rurioctocog alfa pegol 💬 Rurioctocog alfa pegol 1件: 288 💬
13 Complement and coagulation cascades 💬
 1件: F8 💬 Susoctocog alfa 💬 Susoctocog alfa 1件: 288 💬
14 Complement and coagulation cascades 💬
 1件: PLG 💬 Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
15 Cytokine-cytokine receptor interaction 💬
 1件: IL11RA 💬 Oprelvekin 💬 Oprelvekin 3件: 96, 97, 288 💬
16 Hematopoietic cell lineage 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
17 Hematopoietic cell lineage 💬
 1件: IL11RA 💬 Oprelvekin 💬 Oprelvekin 3件: 96, 97, 288 💬
18 Hematopoietic cell lineage 💬
 1件: MS4A1 💬 Rituximab 💬 Rituximab 52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
19 Hormone signaling 💬
 1件: AVPR2 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
20 Hormone signaling 💬
 1件: AVPR2 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
21 Huntington disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
22 Influenza A 💬
 1件: PLG 💬 Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
23 JAK-STAT signaling pathway 💬
 1件: IL11RA 💬 Oprelvekin 💬 Oprelvekin 3件: 96, 97, 288 💬
24 Neuroactive ligand-receptor interaction 💬
 1件: AVPR2 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
25 Neuroactive ligand-receptor interaction 💬
 1件: AVPR2 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
26 Neuroactive ligand-receptor interaction 💬
 1件: NR3C1 💬 Prednisone 💬 Prednisone 54件:  2 , 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
27 Neuroactive ligand-receptor interaction 💬
 1件: PLG 💬 Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
28 Nicotinate and nicotinamide metabolism 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
29 Oxytocin signaling pathway 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
30 Pancreatic secretion 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
31 Parkinson disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
32 Pathways of neurodegeneration - multiple diseases 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
33 Phospholipase D signaling pathway 💬
 1件: AVPR2 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
34 Phospholipase D signaling pathway 💬
 1件: AVPR2 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
35 Prion disease 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
36 Proteasome 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
37 Salivary secretion 💬
 1件: CD38 💬 Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
38 Spinocerebellar ataxia 💬
 1件: PSMB5 💬 Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬
39 Staphylococcus aureus infection 💬
 1件: PLG 💬 Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
40 Terpenoid backbone biosynthesis 💬
 1件: HMGCR 💬 Simvastatin 💬 Simvastatin 21件:  6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
41 Vasopressin-regulated water reabsorption 💬
 1件: AVPR2 💬 Desmopressin 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬
42 Vasopressin-regulated water reabsorption 💬
 1件: AVPR2 💬 Desmopressin acetate 💬 Desmopressin 6件:  6 , 64, 72, 75, 225, 288 💬

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