Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 AVPR2 💬 4件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Vasopressin-regulated water reabsorption Desmopressin 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
2 AVPR2 💬 4件: Phospholipase D signaling pathway, Neuroactive ligand-receptor interaction, Hormone signaling, Vasopressin-regulated water reabsorption Desmopressin acetate 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
3 CD38 💬 6件: Nicotinate and nicotinamide metabolism, Calcium signaling pathway, Hematopoietic cell lineage, Oxytocin signaling pathway, Salivary secretion, Pancreatic secretion Daratumumab 💬 Daratumumab 10件: 13, 16, 28, 46, 48, 49, 60, 63, 288, 331 💬
4 F10 💬 1件: Complement and coagulation cascades Emicizumab 💬 Emicizumab 1件: 288 💬
5 F7 💬 1件: Complement and coagulation cascades Eptacog alfa 💬 Coagulation factor VIIa Recombinant Human 1件: 288 💬
6 F8 💬 1件: Complement and coagulation cascades Octocog alfa 💬 Antihemophilic factor, human recombinant 1件: 288 💬
7 F8 💬 1件: Complement and coagulation cascades Rurioctocog alfa pegol 💬 Rurioctocog alfa pegol 1件: 288 💬
8 F8 💬 1件: Complement and coagulation cascades Desmopressin 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
9 F8 💬 1件: Complement and coagulation cascades Susoctocog alfa 💬 Susoctocog alfa 1件: 288 💬
10 F8 💬 1件: Complement and coagulation cascades Desmopressin acetate 💬 Desmopressin 6件: 6, 64, 72, 75, 225, 288 💬
11 F8 💬 1件: Complement and coagulation cascades Efanesoctocog alfa 💬 Efanesoctocog alfa 1件: 288 💬
12 F9 💬 1件: Complement and coagulation cascades Emicizumab 💬 Emicizumab 1件: 288 💬
13 HMGCR 💬 3件: Terpenoid backbone biosynthesis, AMPK signaling pathway, Bile secretion Simvastatin 💬 Simvastatin 21件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬
14 IL11RA 💬 3件: Cytokine-cytokine receptor interaction, JAK-STAT signaling pathway, Hematopoietic cell lineage Oprelvekin 💬 Oprelvekin 3件: 96, 97, 288 💬
15 MS4A1 💬 1件: Hematopoietic cell lineage Rituximab 💬 Rituximab 52件: 11, 13, 14, 19, 26, 34, 35, 36, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 62, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 172, 220, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬
16 NR3C1 💬 1件: Neuroactive ligand-receptor interaction Prednisone 💬 Prednisone 54件: 2, 11, 13, 14, 18, 19, 26, 28, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 60, 61, 63, 64, 65, 66, 79, 81, 84, 85, 86, 90, 93, 95, 96, 97, 113, 145, 162, 164, 205, 222, 224, 228, 251, 269, 283, 285, 288, 299, 300, 303, 307, 331 💬
17 PLG 💬 4件: Neuroactive ligand-receptor interaction, Complement and coagulation cascades, Staphylococcus aureus infection, Influenza A Tranexamic acid 💬 Tranexamic acid 8件: 46, 65, 70, 215, 227, 274, 288, 299 💬
18 PSMB5 💬 8件: Proteasome, Alzheimer disease, Parkinson disease, Amyotrophic lateral sclerosis, Huntington disease, Spinocerebellar ataxia, Prion disease, Pathways of neurodegeneration - multiple diseases Bortezomib 💬 Bortezomib 18件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 64, 66, 172, 222, 228, 256, 283, 288, 331 💬