Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Inflammatory mediator regulation of TRP channels 💬
 1件: BDKRB2 💬 Deucrictibant 💬 Deucrictibant 1件: 65 💬
2 Inflammatory mediator regulation of TRP channels 💬
 1件: BDKRB2 💬 Icatibant acetate 💬 Icatibant 1件: 65 💬
3 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Cetirizine hydrochloride 💬 Cetirizine 6件: 13, 19, 28, 35, 300, 309 💬
4 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Cetirizine 💬 Cetirizine 6件: 13, 19, 28, 35, 300, 309 💬
5 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Chlorpheniramine maleate 💬 Chlorpheniramine 1件: 14 💬
6 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Chlorphenamine 💬 Chlorpheniramine 1件: 14 💬
7 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Clemastine fumarate 💬 Clemastine 2件: 13, 179 💬
8 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Clemastine 💬 Clemastine 2件: 13, 179 💬
9 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Desloratadine 💬 Desloratadine 1件: 13 💬
10 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Dexchlorpheniramine 💬 Dexchlorpheniramine 1件: 13 💬
11 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Diphenhydramine 💬 Diphenhydramine 11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
12 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Diphenhydramine hydrochloride 💬 Diphenhydramine 11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
13 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Diphenhydramine salicylate 💬 Diphenhydramine 11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
14 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Diphenhydramine citrate 💬 Diphenhydramine 11件: 11, 13, 19, 49, 51, 70, 86, 96, 222, 256, 300 💬
15 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Doxepin hydrochloride 💬 Doxepin 1件:  6  💬
16 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Doxepin 💬 Doxepin 1件:  6  💬
17 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Fexofenadine hydrochloride 💬 Fexofenadine 4件:  6 , 13, 19, 46 💬
18 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Fexofenadine 💬 Fexofenadine 4件:  6 , 13, 19, 46 💬
19 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Histamine phosphate 💬 Histamine 1件: 13 💬
20 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Histamine 💬 Histamine 1件: 13 💬
21 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Levocetirizine 💬 Levocetirizine 1件: 61 💬
22 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Levocetirizine dihydrochloride 💬 Levocetirizine 1件: 61 💬
23 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Loratadine 💬 Loratadine 5件: 13, 19, 46, 89, 98 💬
24 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Promethazine hydrochloride 💬 Promethazine 2件:  6 , 96 💬
25 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Promethazine 💬 Promethazine 2件:  6 , 96 💬
26 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Promethazine teoclate 💬 Promethazine 2件:  6 , 96 💬
27 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Rupatadine 💬 Rupatadine 1件: 46 💬
28 Inflammatory mediator regulation of TRP channels 💬
 1件: HRH1 💬 Rupatadine fumarate 💬 Rupatadine 1件: 46 💬
29 Inflammatory mediator regulation of TRP channels 💬
 4件: HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine hydrochloride 💬 Chlorpromazine 1件: 254 💬
30 Inflammatory mediator regulation of TRP channels 💬
 4件: HRH1, HTR2, HTR2, HTR2 💬 Olanzapine pamoate 💬 Olanzapine 2件:  2 ,  8  💬
31 Inflammatory mediator regulation of TRP channels 💬
 4件: HRH1, HTR2, HTR2, HTR2 💬 Chlorpromazine 💬 Chlorpromazine 1件: 254 💬
32 Inflammatory mediator regulation of TRP channels 💬
 4件: HRH1, HTR2, HTR2, HTR2 💬 Olanzapine 💬 Olanzapine 2件:  2 ,  8  💬
33 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Aripiprazole 💬 Aripiprazole 2件:  6 , 206 💬
34 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Cisapride 💬 Cisapride 1件: 13 💬
35 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Cisapride 💬 Cisapride 1件: 13 💬
36 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Nelotanserin 💬 Nelotanserin 1件:  6  💬
37 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Psilocybin 💬 Psilocybin 4件:  2 ,  6 , 13, 206 💬
38 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Quetiapine fumarate 💬 Quetiapine 1件:  6  💬
39 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Quetiapine 💬 Quetiapine 1件:  6  💬
40 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Risperidone 💬 Risperidone 3件:  8 , 156, 187 💬
41 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Agomelatine 💬 Agomelatine 1件:  6  💬
42 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Lorcaserin hydrochloride 💬 Lorcaserin 1件: 140 💬
43 Inflammatory mediator regulation of TRP channels 💬
 1件: HTR2 💬 Lorcaserin hydrochloride hemihydrate 💬 Lorcaserin 1件: 140 💬
44 Inflammatory mediator regulation of TRP channels 💬
 2件: HTR2, HTR2 💬 Clozapine 💬 Clozapine 1件:  6  💬
45 Inflammatory mediator regulation of TRP channels 💬
 2件: HTR2, HTR2 💬 Fenfluramine 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
46 Inflammatory mediator regulation of TRP channels 💬
 2件: HTR2, HTR2 💬 Pimavanserin tartrate 💬 Pimavanserin 1件:  6  💬
47 Inflammatory mediator regulation of TRP channels 💬
 2件: HTR2, HTR2 💬 Fenfluramine hydrochloride 💬 Fenfluramine 4件: 140, 144, 145, 149 💬
48 Inflammatory mediator regulation of TRP channels 💬
 3件: HTR2, HTR2, HTR2 💬 Trazodone 💬 Trazodone 1件:  2  💬
49 Inflammatory mediator regulation of TRP channels 💬
 3件: HTR2, HTR2, HTR2 💬 Iloperidone 💬 Iloperidone 1件:  6  💬
50 Inflammatory mediator regulation of TRP channels 💬
 3件: HTR2, HTR2, HTR2 💬 Mirtazapine 💬 Mirtazapine 3件:  6 , 85, 97 💬
51 Inflammatory mediator regulation of TRP channels 💬
 3件: HTR2, HTR2, HTR2 💬 Trazodone hydrochloride 💬 Trazodone 1件:  2  💬
52 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
53 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
54 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
55 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1B 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
56 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
57 Inflammatory mediator regulation of TRP channels 💬
 1件: IL1R1 💬 Anakinra 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
58 Inflammatory mediator regulation of TRP channels 💬
 1件: NGFB 💬 Tanezumab 💬 Tanezumab 2件: 226, 298 💬
59 Inflammatory mediator regulation of TRP channels 💬
 1件: P2RY2 💬 Denufosol tetrasodium 💬 Denufosol 1件: 299 💬
60 Inflammatory mediator regulation of TRP channels 💬
 1件: P2RY2 💬 Diquafosol tetrasodium 💬 Diquafosol 1件: 53 💬
61 Inflammatory mediator regulation of TRP channels 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
62 Inflammatory mediator regulation of TRP channels 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
63 Inflammatory mediator regulation of TRP channels 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
64 Inflammatory mediator regulation of TRP channels 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
65 Inflammatory mediator regulation of TRP channels 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
66 Inflammatory mediator regulation of TRP channels 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
67 Inflammatory mediator regulation of TRP channels 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
68 Inflammatory mediator regulation of TRP channels 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
69 Inflammatory mediator regulation of TRP channels 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
70 Inflammatory mediator regulation of TRP channels 💬
 4件: PRKCD, PRKCE, PRKCH, PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
71 Inflammatory mediator regulation of TRP channels 💬
 4件: PRKCD, PRKCE, PRKCH, PRKCQ 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
72 Inflammatory mediator regulation of TRP channels 💬
 2件: PTGER2, PTGER4 💬 Misoprostol 💬 Misoprostol 3件: 46, 70, 271 💬
73 Inflammatory mediator regulation of TRP channels 💬
 1件: SRC 💬 Bosutinib 💬 Bosutinib 2件:  2 , 67 💬
74 Inflammatory mediator regulation of TRP channels 💬
 1件: SRC 💬 Bosutinib hydrate 💬 Bosutinib 2件:  2 , 67 💬
75 Inflammatory mediator regulation of TRP channels 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
76 Inflammatory mediator regulation of TRP channels 💬
 1件: SRC 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
77 Inflammatory mediator regulation of TRP channels 💬
 1件: SRC 💬 Saracatinib 💬 Saracatinib 3件:  6 , 89, 272 💬
78 Inflammatory mediator regulation of TRP channels 💬
 1件: TRPV1 💬 Capsaicin 💬 Capsaicin 4件:  2 ,  6 , 86, 226 💬