Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Primary immunodeficiency 💬
 1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
2 Primary immunodeficiency 💬
 1件: BTK 💬 Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
3 Primary immunodeficiency 💬
 1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
4 Primary immunodeficiency 💬
 1件: BTK 💬 Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
5 Primary immunodeficiency 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
6 Primary immunodeficiency 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
7 Primary immunodeficiency 💬
 1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
8 Primary immunodeficiency 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
9 Primary immunodeficiency 💬
 1件: BTK 💬 Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
10 Primary immunodeficiency 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
11 Primary immunodeficiency 💬
 1件: BTK 💬 Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
12 Primary immunodeficiency 💬
 1件: BTK 💬 Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
13 Primary immunodeficiency 💬
 1件: BTK 💬 Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
14 Primary immunodeficiency 💬
 1件: BTK 💬 Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
15 Primary immunodeficiency 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
16 Primary immunodeficiency 💬
 1件: CD19 💬 Inebilizumab 💬 Inebilizumab 6件: 11, 13, 46, 49, 51, 300 💬
17 Primary immunodeficiency 💬
 1件: CD19 💬 Obecabtagene autoleucel 💬 Obecabtagene autoleucel 1件: 49 💬
18 Primary immunodeficiency 💬
 1件: CD19 💬 Obexelimab 💬 Obexelimab 4件: 13, 49, 61, 300 💬
19 Primary immunodeficiency 💬
 1件: CD19 💬 Tafasitamab 💬 Tafasitamab 1件: 51 💬
20 Primary immunodeficiency 💬
 3件: CD19, CD3D, CD3E 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
21 Primary immunodeficiency 💬
 2件: CD3D, CD3E 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
22 Primary immunodeficiency 💬
 2件: CD3D, CD3E 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
23 Primary immunodeficiency 💬
 2件: CD3D, CD3E 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
24 Primary immunodeficiency 💬
 5件: CD3D, CD3E, CD4, CD8A, CD8B 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
25 Primary immunodeficiency 💬
 1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
26 Primary immunodeficiency 💬
 1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
27 Primary immunodeficiency 💬
 1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
28 Primary immunodeficiency 💬
 1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
29 Primary immunodeficiency 💬
 1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
30 Primary immunodeficiency 💬
 1件: CD4 💬 Zanolimumab 💬 Zanolimumab 1件: 46 💬
31 Primary immunodeficiency 💬
 1件: ICOS 💬 Acazicolcept 💬 Acazicolcept 1件: 49 💬
32 Primary immunodeficiency 💬
 1件: IL2RG 💬 Aldesleukin 💬 Aldesleukin 6件:  2 , 35, 49, 65, 96, 97 💬
33 Primary immunodeficiency 💬
 1件: IL7R 💬 Lusvertikimab 💬 Lusvertikimab 1件: 97 💬
34 Primary immunodeficiency 💬
 1件: JAK3 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
35 Primary immunodeficiency 💬
 1件: JAK3 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
36 Primary immunodeficiency 💬
 1件: JAK3 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
37 Primary immunodeficiency 💬
 1件: JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
38 Primary immunodeficiency 💬
 1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
39 Primary immunodeficiency 💬
 1件: JAK3 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
40 Primary immunodeficiency 💬
 1件: JAK3 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
41 Primary immunodeficiency 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
42 Primary immunodeficiency 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
43 Primary immunodeficiency 💬
 1件: TNFRSF13B 💬 Povetacicept 💬 Povetacicept 3件: 61, 63, 222 💬
44 Primary immunodeficiency 💬
 1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
45 Primary immunodeficiency 💬
 1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
46 Primary immunodeficiency 💬
 1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
47 Primary immunodeficiency 💬
 1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
48 Primary immunodeficiency 💬
 1件: TNFSF5 💬 Frexalimab 💬 Frexalimab 2件: 13, 222 💬
49 Primary immunodeficiency 💬
 1件: TNFSF5 💬 Toralizumab 💬 Toralizumab 1件: 63 💬
50 Primary immunodeficiency 💬
 1件: add 💬 Elapegademase 💬 Elapegademase 1件: 65 💬
51 Primary immunodeficiency 💬
 1件: add 💬 Pentostatin 💬 Pentostatin 1件: 60 💬