Target Gene/Pathway Pathway / Gene


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No. KEGG GENES KEGG PATHWAY KEGG DRUG DrugBank 指定難病告示番号
1 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
2 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
3 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
4 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
5 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
6 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
7 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
8 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
9 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
10 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
11 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
12 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
13 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
14 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
15 BTK 💬 7件: NF-kappa B signaling pathway, Osteoclast differentiation, Platelet activation, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Epstein-Barr virus infection, Primary immunodeficiency Fenebrutinib 💬 Fenebrutinib 1件: 13 💬