Target Gene/Pathway Pathway / Gene


Search results


No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Purine metabolism 💬
3件: GUCY1A, GUCY1A, GUCY1B 💬 Riociguat 💬 Riociguat 6件: 51, 84, 86, 88, 225, 299 💬
2 Purine metabolism 💬
3件: GUCY1A, GUCY1A, GUCY1B 💬 Vericiguat 💬 Vericiguat 1件: 86 💬
3 Purine metabolism 💬
3件: GUCY1A, GUCY1A, GUCY1B 💬 Zagociguat 💬 Zagociguat 1件: 21 💬
4 Purine metabolism 💬
3件: GUCY1A, GUCY1A, GUCY1B 💬 Amyl nitrite 💬 Amyl Nitrite 1件: 58 💬
5 Purine metabolism 💬
3件: GUCY1A, GUCY1A, GUCY1B 💬 Avenciguat 💬 Avenciguat 1件: 51 💬
6 Purine metabolism 💬
1件: GUCY2C 💬 Linaclotide acetate 💬 Linaclotide 2件:  6 , 97 💬
7 Purine metabolism 💬
1件: GUCY2C 💬 Linaclotide 💬 Linaclotide 2件:  6 , 97 💬
8 Purine metabolism 💬
2件: IMPDH, IMPDH 💬 Mycophenolate mofetil 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
9 Purine metabolism 💬
2件: IMPDH, IMPDH 💬 Mycophenolate mofetil hydrochloride 💬 Mycophenolate mofetil 34件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 93, 95, 96, 164, 222, 224, 226, 234, 283, 284, 285, 300 💬
10 Purine metabolism 💬
2件: IMPDH, IMPDH 💬 Mizoribine 💬 Mizoribine 8件: 46, 49, 51, 53, 66, 94, 222, 224 💬
11 Purine metabolism 💬
2件: IMPDH, IMPDH 💬 Mycophenolate sodium 💬 Mycophenolic acid 37件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
12 Purine metabolism 💬
2件: IMPDH, IMPDH 💬 Mycophenolic acid 💬 Mycophenolic acid 37件:  2 , 11, 13, 19, 20, 28, 35, 36, 42, 43, 44, 45, 46, 49, 51, 53, 60, 61, 62, 63, 65, 66, 84, 93, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 💬
13 Purine metabolism 💬
1件: NPR1 💬 Nesiritide 💬 Nesiritide 1件: 58 💬
14 Purine metabolism 💬
2件: NPR1, NPR2 💬 Erythrityl tetranitrate 💬 Erythrityl tetranitrate 1件: 46 💬
15 Purine metabolism 💬
1件: NPR2 💬 Vosoritide 💬 Vosoritide 3件: 19, 195, 276 💬
16 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Flavoxate hydrochloride 💬 Flavoxate 1件: 226 💬
17 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Flavoxate 💬 Flavoxate 1件: 226 💬
18 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Aminophylline dihydrate 💬 Aminophylline 1件: 63 💬
19 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Theophylline sodium glycinate 💬 Theophylline 2件: 236, 299 💬
20 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
21 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Bucladesine 💬 Bucladesine 1件: 246 💬
22 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Theophylline 💬 Theophylline 2件: 236, 299 💬
23 Purine metabolism 💬
16件: PDE1, PDE1, PDE1, PDE10, PDE11, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE7, PDE7, PDE8, PDE8 💬 Aminophylline 💬 Aminophylline 1件: 63 💬
24 Purine metabolism 💬
9件: PDE1, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE5 💬 Caffeine hydrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
25 Purine metabolism 💬
9件: PDE1, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE5 💬 Caffeine citrate 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
26 Purine metabolism 💬
9件: PDE1, PDE2A, PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4, PDE5 💬 Caffeine 💬 Caffeine 8件:  2 ,  6 , 13, 21, 46, 96, 97, 265 💬
27 Purine metabolism 💬
2件: PDE3A, PDE3B 💬 Cilostazol 💬 Cilostazol 5件:  6 , 46, 51, 70, 124 💬
28 Purine metabolism 💬
2件: PDE3A, PDE3B 💬 Levosimendan 💬 Levosimendan 1件:  2  💬
29 Purine metabolism 💬
2件: PDE3A, PDE3B 💬 Milrinone 💬 Milrinone 1件: 294 💬
30 Purine metabolism 💬
2件: PDE3A, PDE3B 💬 Milrinone lactate 💬 Milrinone 1件: 294 💬
31 Purine metabolism 💬
6件: PDE3A, PDE3B, PDE4, PDE4, PDE4, PDE4 💬 Ibudilast 💬 Ibudilast 2件:  2 , 13 💬
32 Purine metabolism 💬
1件: PDE4 💬 Zatolmilast 💬 Zatolmilast 1件: 206 💬
33 Purine metabolism 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Rolipram 💬 Rolipram 2件:  8 , 13 💬
34 Purine metabolism 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Apremilast 💬 Apremilast 8件: 36, 46, 50, 56, 97, 107, 162, 271 💬
35 Purine metabolism 💬
4件: PDE4, PDE4, PDE4, PDE4 💬 Roflumilast 💬 Roflumilast 4件: 84, 97, 206, 299 💬
36 Purine metabolism 💬
2件: PDE4, PDE5 💬 Dipyridamole 💬 Dipyridamole 5件: 46, 51, 66, 96, 224 💬
37 Purine metabolism 💬
1件: PDE5 💬 Sildenafil citrate 💬 Sildenafil 14件:  6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
38 Purine metabolism 💬
1件: PDE5 💬 Sildenafil 💬 Sildenafil 14件:  6 , 46, 51, 85, 86, 113, 210, 211, 212, 225, 226, 278, 294, 299 💬
39 Purine metabolism 💬
1件: PDE5 💬 Tadalafil 💬 Tadalafil 8件:  6 , 51, 75, 77, 84, 86, 113, 210 💬
40 Purine metabolism 💬
1件: PDE5 💬 Udenafil 💬 Udenafil 2件: 86, 210 💬
41 Purine metabolism 💬
1件: PDE5 💬 Vardenafil 💬 Vardenafil 3件: 13, 86, 299 💬
42 Purine metabolism 💬
1件: PDE5 💬 Vardenafil hydrochloride 💬 Vardenafil 3件: 13, 86, 299 💬
43 Purine metabolism 💬
1件: RRM1 💬 Cladribine 💬 Cladribine 3件: 11, 13, 94 💬
44 Purine metabolism 💬
1件: RRM1 💬 Clofarabine 💬 Clofarabine 5件: 19, 20, 60, 96, 234 💬
45 Purine metabolism 💬
1件: RRM1 💬 Fludarabine phosphate 💬 Fludarabine 25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
46 Purine metabolism 💬
1件: RRM1 💬 Fludarabine 💬 Fludarabine 25件: 11, 13, 19, 28, 34, 35, 36, 44, 46, 49, 51, 60, 61, 62, 65, 85, 96, 107, 164, 222, 283, 284, 285, 286, 326 💬
47 Purine metabolism 💬
1件: RRM2 💬 Hydroxyurea 💬 Hydroxyurea 10件:  3 , 13, 19, 20, 46, 65, 85, 86, 107, 284 💬
48 Purine metabolism 💬
1件: XDH 💬 Allopurinol 💬 Allopurinol 7件:  6 , 46, 57, 60, 66, 96, 97 💬
49 Purine metabolism 💬
1件: XDH 💬 Allopurinol sodium 💬 Allopurinol 7件:  6 , 46, 57, 60, 66, 96, 97 💬
50 Purine metabolism 💬
1件: XDH 💬 Febuxostat 💬 Febuxostat 4件:  2 ,  6 , 13, 97 💬
51 Purine metabolism 💬
1件: XDH 💬 Febuxostat hydrate 💬 Febuxostat 4件:  2 ,  6 , 13, 97 💬
52 Purine metabolism 💬
1件: add 💬 Elapegademase 💬 Elapegademase 1件: 65 💬
53 Purine metabolism 💬
1件: add 💬 Pentostatin 💬 Pentostatin 1件: 60 💬
54 Purine metabolism 💬
1件: hprT 💬 Mercaptopurine 💬 Mercaptopurine 2件: 96, 97 💬
55 Purine metabolism 💬
1件: hprT 💬 Mercaptopurine 💬 Mercaptopurine 2件: 96, 97 💬
56 Purine metabolism 💬
1件: hprT 💬 Thioguanine 💬 Tioguanine 1件: 13 💬
57 Purine metabolism 💬
1件: hprT 💬 Tioguanine 💬 Tioguanine 1件: 13 💬