Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 NF-kappa B signaling pathway 💬
 1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 NF-kappa B signaling pathway 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
4 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
5 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
6 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
7 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
8 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
9 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
10 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
11 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
12 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
13 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
14 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
15 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
16 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
17 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
18 NF-kappa B signaling pathway 💬
 1件: ICAM1 💬 Alicaforsen sodium 💬 Alicaforsen 2件: 96, 97 💬
19 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 11件: 46, 54, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
20 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
21 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Lutikizumab 💬 Lutikizumab 3件: 46, 96, 97 💬
22 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Rilonacept 💬 Rilonacept 5件: 51, 84, 106, 107, 266 💬
23 NF-kappa B signaling pathway 💬
 2件: IL1B, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
24 NF-kappa B signaling pathway 💬
 1件: IL1R1 💬 Anakinra 💬 Anakinra 19件:  2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 54, 56, 84, 86, 97, 106, 107, 266, 299 💬
25 NF-kappa B signaling pathway 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
26 NF-kappa B signaling pathway 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
27 NF-kappa B signaling pathway 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬
28 NF-kappa B signaling pathway 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
29 NF-kappa B signaling pathway 💬
 1件: LTB 💬 Baminercept 💬 Baminercept 4件: 13, 46, 53, 97 💬
30 NF-kappa B signaling pathway 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
31 NF-kappa B signaling pathway 💬
 1件: PARP1 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬
32 NF-kappa B signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
33 NF-kappa B signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
34 NF-kappa B signaling pathway 💬
 1件: PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
35 NF-kappa B signaling pathway 💬
 1件: PRKCQ 💬 Sotrastaurin acetate 💬 Sotrastaurin 1件: 97 💬
36 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
37 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 18件:  3 ,  6 , 11, 13, 19, 34, 35, 46, 49, 51, 70, 77, 86, 96, 222, 256, 300, 337 💬
38 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 15件: 13, 22, 34, 46, 49, 51, 64, 86, 96, 97, 113, 158, 210, 231, 271 💬
39 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 14件:  2 ,  3 ,  6 , 13, 34, 46, 70, 89, 96, 97, 107, 161, 171, 271 💬
40 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac potassium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
41 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac sodium 💬 Diclofenac 4件: 13, 34, 46, 271 💬
42 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 4件: 13, 34, 46, 271 💬
43 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac diethylamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
44 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac epolamine 💬 Diclofenac 4件: 13, 34, 46, 271 💬
45 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
46 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 3件: 46, 70, 271 💬
47 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
48 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Flurbiprofen sodium 💬 Flurbiprofen 3件: 13, 21, 46 💬
49 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
50 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen aluminum 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
51 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen lysine 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
52 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
53 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen sodium 💬 Ibuprofen 6件: 13, 46, 65, 113, 271, 299 💬
54 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
55 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Indomethacin sodium 💬 Indomethacin 3件: 225, 271, 298 💬
56 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 2件: 13, 46 💬
57 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketoprofen lysine 💬 Ketoprofen 2件: 13, 46 💬
58 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketoprofen sodium 💬 Ketoprofen 2件: 13, 46 💬
59 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketorolac tromethamine 💬 Ketorolac 2件: 70, 226 💬
60 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
61 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
62 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
63 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 3件: 46, 271, 296 💬
64 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
65 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Naproxen sodium 💬 Naproxen 4件: 13, 46, 107, 271 💬
66 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
67 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Valdecoxib 💬 Parecoxib 2件: 46, 271 💬
68 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
69 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Parecoxib sodium 💬 Parecoxib 2件: 46, 271 💬
70 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
71 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
72 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
73 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
74 NF-kappa B signaling pathway 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
75 NF-kappa B signaling pathway 💬
 1件: RIPK1 💬 Eclitasertib 💬 SAR443122 1件: 97 💬
76 NF-kappa B signaling pathway 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
77 NF-kappa B signaling pathway 💬
 1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
78 NF-kappa B signaling pathway 💬
 1件: SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
79 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
80 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
81 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
82 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
83 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
84 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
85 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
86 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
87 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
88 NF-kappa B signaling pathway 💬
 1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 8件: 35, 46, 49, 51, 53, 61, 63, 95 💬
89 NF-kappa B signaling pathway 💬
 1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
90 NF-kappa B signaling pathway 💬
 1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
91 NF-kappa B signaling pathway 💬
 1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
92 NF-kappa B signaling pathway 💬
 1件: TNFSF11 💬 Denosumab 💬 Denosumab 10件: 46, 50, 70, 75, 77, 93, 95, 96, 274, 299 💬
93 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Atacicept 💬 Atacicept 5件: 13, 46, 49, 66, 222 💬
94 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Belimumab 💬 Belimumab 14件: 11, 13, 43, 44, 46, 48, 49, 51, 53, 63, 66, 95, 222, 296 💬
95 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Rozibafusp alfa 💬 Rozibafusp Alfa 2件: 46, 49 💬
96 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Tabalumab 💬 Tabalumab 2件: 46, 49 💬
97 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Tibulizumab 💬 Tibulizumab 2件: 51, 53 💬
98 NF-kappa B signaling pathway 💬
 1件: TNFSF5 💬 Frexalimab 💬 Frexalimab 2件: 13, 222 💬
99 NF-kappa B signaling pathway 💬
 1件: TNFSF5 💬 Toralizumab 💬 Toralizumab 1件: 63 💬