Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 NF-kappa B signaling pathway 💬
 1件: BCL2 💬 Venetoclax 💬 Venetoclax 1件: 28 💬
2 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
3 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
4 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
5 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
6 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
7 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
8 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 2件: 13, 53 💬
9 NF-kappa B signaling pathway 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 5件: 13, 63, 222, 300, 331 💬
10 NF-kappa B signaling pathway 💬
 1件: CD40 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
11 NF-kappa B signaling pathway 💬
 1件: CD40 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
12 NF-kappa B signaling pathway 💬
 1件: CD40 💬 Ravagalimab 💬 Ravagalimab 2件: 53, 97 💬
13 NF-kappa B signaling pathway 💬
 1件: CD40LG 💬 Toralizumab 💬 Toralizumab 1件: 63 💬
14 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Canakinumab 💬 Canakinumab 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬
15 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Gevokizumab 💬 Gevokizumab 4件: 41, 50, 56, 269 💬
16 NF-kappa B signaling pathway 💬
 1件: IL1B 💬 Rilonacept 💬 Rilonacept 4件: 51, 106, 107, 266 💬
17 NF-kappa B signaling pathway 💬
 2件: IL1B, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
18 NF-kappa B signaling pathway 💬
 1件: IL1R1 💬 Anakinra 💬 Anakinra 18件:  2 , 13, 15, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬
19 NF-kappa B signaling pathway 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
20 NF-kappa B signaling pathway 💬
 1件: LCK 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
21 NF-kappa B signaling pathway 💬
 1件: LTA 💬 Pateclizumab 💬 Pateclizumab 1件: 46 💬
22 NF-kappa B signaling pathway 💬
 2件: LTA, TNF 💬 Etanercept 💬 Etanercept 16件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285 💬
23 NF-kappa B signaling pathway 💬
 1件: LTB 💬 Baminercept 💬 Baminercept 4件: 13, 46, 53, 97 💬
24 NF-kappa B signaling pathway 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 5件: 46, 51, 53, 271, 300 💬
25 NF-kappa B signaling pathway 💬
 1件: PARP1 💬 Olaparib 💬 Olaparib 2件: 86, 285 💬
26 NF-kappa B signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
27 NF-kappa B signaling pathway 💬
 1件: PRKCQ 💬 Sotrastaurin 💬 Sotrastaurin 1件: 97 💬
28 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Aceclofenac 💬 Aceclofenac 1件: 46 💬
29 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Acetaminophen 💬 Acetaminophen 15件:  3 ,  6 , 11, 13, 34, 35, 46, 49, 51, 70, 86, 222, 256, 271, 337 💬
30 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Aspirin 💬 Acetylsalicylic acid 14件: 13, 22, 46, 49, 51, 58, 64, 86, 97, 113, 158, 210, 231, 251 💬
31 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Celecoxib 💬 Celecoxib 10件:  2 ,  3 , 34, 46, 70, 89, 107, 161, 171, 271 💬
32 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diclofenac 💬 Diclofenac 5件: 13, 34, 46, 78, 271 💬
33 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Diflunisal 💬 Diflunisal 1件: 28 💬
34 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Etodolac 💬 Etodolac 1件: 46 💬
35 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Etoricoxib 💬 Etoricoxib 2件: 46, 271 💬
36 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Flurbiprofen 💬 Flurbiprofen 3件: 13, 21, 46 💬
37 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ibuprofen 💬 Ibuprofen 7件: 13, 46, 65, 107, 113, 271, 299 💬
38 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Indomethacin 💬 Indomethacin 3件: 225, 271, 298 💬
39 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketoprofen 💬 Ketoprofen 1件: 46 💬
40 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Ketorolac 💬 Ketorolac 2件: 70, 226 💬
41 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Loxoprofen 💬 Loxoprofen 2件: 46, 271 💬
42 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Lumiracoxib 💬 Lumiracoxib 1件: 46 💬
43 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Meloxicam 💬 Meloxicam 4件: 46, 49, 271, 296 💬
44 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Naproxen 💬 Naproxen 4件: 13, 46, 107, 271 💬
45 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Nimesulide 💬 Nimesulide 1件: 46 💬
46 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Parecoxib 💬 Parecoxib 2件: 46, 271 💬
47 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Rofecoxib 💬 Rofecoxib 1件: 46 💬
48 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Salsalate 💬 Salsalate 1件:  5  💬
49 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Sulindac 💬 Sulindac 1件: 206 💬
50 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Tolfenamic acid 💬 Tolfenamic acid 1件:  5  💬
51 NF-kappa B signaling pathway 💬
 1件: PTGS2 💬 Valdecoxib 💬 Valdecoxib 1件: 46 💬
52 NF-kappa B signaling pathway 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
53 NF-kappa B signaling pathway 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 4件: 46, 49, 61, 66 💬
54 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 17件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 107, 160, 164, 222, 226, 269, 270, 271 💬
55 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 8件: 37, 46, 49, 96, 97, 107, 226, 271 💬
56 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
57 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 27件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 107, 162, 164, 269, 270, 271 💬
58 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
59 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
60 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
61 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 5件: 28, 51, 85, 227, 331 💬
62 NF-kappa B signaling pathway 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 20件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 300, 331 💬
63 NF-kappa B signaling pathway 💬
 1件: TNFRSF13C 💬 Ianalumab 💬 Ianalumab 7件: 35, 46, 49, 53, 61, 63, 95 💬
64 NF-kappa B signaling pathway 💬
 1件: TNFSF11 💬 Denosumab 💬 Denosumab 8件: 46, 50, 70, 93, 95, 96, 274, 299 💬
65 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Atacicept 💬 Atacicept 4件: 13, 46, 49, 66 💬
66 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Belimumab 💬 Belimumab 13件: 11, 13, 43, 44, 46, 49, 51, 53, 63, 66, 222, 296, 300 💬
67 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Tabalumab 💬 Tabalumab 2件: 46, 49 💬
68 NF-kappa B signaling pathway 💬
 1件: TNFSF13B 💬 Tibulizumab 💬 Tibulizumab 1件: 53 💬