Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 B cell receptor signaling pathway 💬
 1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
2 B cell receptor signaling pathway 💬
 1件: BTK 💬 Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
3 B cell receptor signaling pathway 💬
 1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
4 B cell receptor signaling pathway 💬
 1件: BTK 💬 Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
5 B cell receptor signaling pathway 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
6 B cell receptor signaling pathway 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
7 B cell receptor signaling pathway 💬
 1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
8 B cell receptor signaling pathway 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
9 B cell receptor signaling pathway 💬
 1件: BTK 💬 Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
10 B cell receptor signaling pathway 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
11 B cell receptor signaling pathway 💬
 1件: BTK 💬 Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
12 B cell receptor signaling pathway 💬
 1件: BTK 💬 Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
13 B cell receptor signaling pathway 💬
 1件: BTK 💬 Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
14 B cell receptor signaling pathway 💬
 1件: BTK 💬 Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
15 B cell receptor signaling pathway 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
16 B cell receptor signaling pathway 💬
 1件: CD19 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
17 B cell receptor signaling pathway 💬
 1件: CD19 💬 Inebilizumab 💬 Inebilizumab 6件: 11, 13, 46, 49, 51, 300 💬
18 B cell receptor signaling pathway 💬
 1件: CD19 💬 Obecabtagene autoleucel 💬 Obecabtagene autoleucel 1件: 49 💬
19 B cell receptor signaling pathway 💬
 1件: CD19 💬 Obexelimab 💬 Obexelimab 4件: 13, 49, 61, 300 💬
20 B cell receptor signaling pathway 💬
 1件: CD19 💬 Tafasitamab 💬 Tafasitamab 1件: 51 💬
21 B cell receptor signaling pathway 💬
 1件: CD22 💬 Epratuzumab 💬 Epratuzumab 1件: 49 💬
22 B cell receptor signaling pathway 💬
 1件: LILR 💬 Daxdilimab 💬 Daxdilimab 2件: 49, 50 💬
23 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
24 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
25 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
26 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
27 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
28 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
29 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
30 B cell receptor signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
31 B cell receptor signaling pathway 💬
 1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
32 B cell receptor signaling pathway 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
33 B cell receptor signaling pathway 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
34 B cell receptor signaling pathway 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
35 B cell receptor signaling pathway 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
36 B cell receptor signaling pathway 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
37 B cell receptor signaling pathway 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Pimecrolimus 💬 Pimecrolimus 1件: 160 💬
38 B cell receptor signaling pathway 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Voclosporin 💬 Voclosporin 2件: 49, 222 💬
39 B cell receptor signaling pathway 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
40 B cell receptor signaling pathway 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Tacrolimus 💬 Tacrolimus 33件:  2 ,  6 , 11, 36, 46, 49, 50, 51, 53, 56, 60, 61, 62, 65, 66, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 227, 228, 234, 283, 284, 285, 286, 299 💬
41 B cell receptor signaling pathway 💬
 5件: PPP3C, PPP3C, PPP3C, PPP3R, PPP3R 💬 Cyclosporine 💬 Cyclosporine 42件: 11, 19, 20, 26, 28, 36, 40, 41, 42, 45, 46, 49, 50, 53, 54, 55, 56, 58, 60, 61, 62, 63, 64, 65, 93, 95, 97, 107, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬
42 B cell receptor signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin hydrochloride 💬 Enzastaurin 1件: 168 💬
43 B cell receptor signaling pathway 💬
 1件: PRKCB 💬 Enzastaurin 💬 Enzastaurin 1件: 168 💬
44 B cell receptor signaling pathway 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
45 B cell receptor signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
46 B cell receptor signaling pathway 💬
 1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
47 B cell receptor signaling pathway 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
48 B cell receptor signaling pathway 💬
 1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
49 B cell receptor signaling pathway 💬
 1件: SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬