Target Gene/Pathway Pathway / Gene

  

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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related 		KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Fc epsilon RI signaling pathway 💬
 1件: ALOX5 💬 Oxatomide 💬 Oxatomide 1件: 113 💬
2 Fc epsilon RI signaling pathway 💬
 1件: ALOX5 💬 Zileuton 💬 Zileuton 3件: 85, 160, 164 💬
3 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
4 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
5 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
6 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
7 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
8 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
9 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
10 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
11 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
12 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
13 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
14 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
15 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
16 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
17 Fc epsilon RI signaling pathway 💬
 1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
18 Fc epsilon RI signaling pathway 💬
 1件: CSF2 💬 Otilimab 💬 Otilimab 1件: 46 💬
19 Fc epsilon RI signaling pathway 💬
 1件: FCER1A 💬 Omalizumab 💬 Omalizumab 7件: 46, 53, 65, 98, 162, 226, 299 💬
20 Fc epsilon RI signaling pathway 💬
 1件: FYN 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
21 Fc epsilon RI signaling pathway 💬
 1件: FYN 💬 Dasatinib 💬 Dasatinib 2件: 51, 85 💬
22 Fc epsilon RI signaling pathway 💬
 1件: IL13 💬 Anrukinzumab 💬 Anrukinzumab 1件: 97 💬
23 Fc epsilon RI signaling pathway 💬
 1件: IL13 💬 Cendakimab 💬 Cendakimab 1件: 98 💬
24 Fc epsilon RI signaling pathway 💬
 1件: IL13 💬 Lebrikizumab 💬 Lebrikizumab 1件: 85 💬
25 Fc epsilon RI signaling pathway 💬
 1件: IL13 💬 Tralokinumab 💬 Tralokinumab 2件: 85, 97 💬
26 Fc epsilon RI signaling pathway 💬
 1件: IL5 💬 Depemokimab 💬 Depemokimab 2件: 44, 45 💬
27 Fc epsilon RI signaling pathway 💬
 1件: IL5 💬 Mepolizumab 💬 Mepolizumab 4件: 44, 45, 98, 162 💬
28 Fc epsilon RI signaling pathway 💬
 1件: IL5 💬 Reslizumab 💬 Reslizumab 2件: 44, 98 💬
29 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Binimetinib 💬 Binimetinib 1件: 34 💬
30 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib 💬 Cobimetinib 1件: 280 💬
31 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Cobimetinib fumarate 💬 Cobimetinib 1件: 280 💬
32 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Mirdametinib 💬 Mirdametinib 4件: 34, 278, 279, 280 💬
33 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib 💬 Selumetinib 1件: 34 💬
34 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Selumetinib sulfate 💬 Selumetinib 1件: 34 💬
35 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
36 Fc epsilon RI signaling pathway 💬
 2件: MAP2K1, MAP2K2 💬 Trametinib dimethyl sulfoxide 💬 Trametinib 6件:  2 , 34, 58, 195, 279, 280 💬
37 Fc epsilon RI signaling pathway 💬
 4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
38 Fc epsilon RI signaling pathway 💬
 4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
39 Fc epsilon RI signaling pathway 💬
 1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
40 Fc epsilon RI signaling pathway 💬
 1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
41 Fc epsilon RI signaling pathway 💬
 1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
42 Fc epsilon RI signaling pathway 💬
 2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
43 Fc epsilon RI signaling pathway 💬
 3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
44 Fc epsilon RI signaling pathway 💬
 1件: RAF1 💬 Sorafenib tosylate 💬 Sorafenib 2件: 34, 86 💬
45 Fc epsilon RI signaling pathway 💬
 1件: RAF1 💬 Sorafenib 💬 Sorafenib 2件: 34, 86 💬
46 Fc epsilon RI signaling pathway 💬
 1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
47 Fc epsilon RI signaling pathway 💬
 1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
48 Fc epsilon RI signaling pathway 💬
 1件: SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
49 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
50 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
51 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
52 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
53 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
54 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
55 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
56 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
57 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
58 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
59 Fc epsilon RI signaling pathway 💬
 1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬