Target Gene/Pathway Pathway / Gene


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No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 Epstein-Barr virus infection 💬
1件: BCL2 💬 Obatoclax mesylate 💬 Obatoclax 1件: 60 💬
2 Epstein-Barr virus infection 💬
1件: BCL2 💬 Venetoclax 💬 Venetoclax 2件: 28, 85 💬
3 Epstein-Barr virus infection 💬
1件: BTK 💬 Acalabrutinib 💬 Acalabrutinib 2件: 46, 61 💬
4 Epstein-Barr virus infection 💬
1件: BTK 💬 Acalabrutinib maleate hydrate 💬 Acalabrutinib 2件: 46, 61 💬
5 Epstein-Barr virus infection 💬
1件: BTK 💬 Branebrutinib 💬 Branebrutinib 3件: 46, 49, 53 💬
6 Epstein-Barr virus infection 💬
1件: BTK 💬 Elsubrutinib 💬 Elsubrutinib 1件: 49 💬
7 Epstein-Barr virus infection 💬
1件: BTK 💬 Evobrutinib 💬 Evobrutinib 3件: 13, 46, 49 💬
8 Epstein-Barr virus infection 💬
1件: BTK 💬 Fenebrutinib 💬 Fenebrutinib 1件: 13 💬
9 Epstein-Barr virus infection 💬
1件: BTK 💬 Ibrutinib 💬 Ibrutinib 3件: 28, 60, 61 💬
10 Epstein-Barr virus infection 💬
1件: BTK 💬 Orelabrutinib 💬 Orelabrutinib 4件: 13, 49, 61, 63 💬
11 Epstein-Barr virus infection 💬
1件: BTK 💬 Pirtobrutinib 💬 Pirtobrutinib 1件: 13 💬
12 Epstein-Barr virus infection 💬
1件: BTK 💬 Remibrutinib 💬 Remibrutinib 3件: 11, 13, 53 💬
13 Epstein-Barr virus infection 💬
1件: BTK 💬 Rilzabrutinib 💬 Rilzabrutinib 5件: 35, 61, 63, 222, 300 💬
14 Epstein-Barr virus infection 💬
1件: BTK 💬 Tirabrutinib hydrochloride 💬 Tirabrutinib 2件: 46, 53 💬
15 Epstein-Barr virus infection 💬
1件: BTK 💬 Tirabrutinib 💬 Tirabrutinib 2件: 46, 53 💬
16 Epstein-Barr virus infection 💬
1件: BTK 💬 Tolebrutinib 💬 Tolebrutinib 2件: 11, 13 💬
17 Epstein-Barr virus infection 💬
1件: BTK 💬 Zanubrutinib 💬 Zanubrutinib 6件: 13, 61, 63, 222, 300, 331 💬
18 Epstein-Barr virus infection 💬
1件: CASP9 💬 Rimiducid 💬 Rimiducid 7件: 19, 49, 60, 65, 284, 285, 326 💬
19 Epstein-Barr virus infection 💬
1件: CD19 💬 Inebilizumab 💬 Inebilizumab 6件: 11, 13, 46, 49, 51, 300 💬
20 Epstein-Barr virus infection 💬
1件: CD19 💬 Obecabtagene autoleucel 💬 Obecabtagene autoleucel 1件: 49 💬
21 Epstein-Barr virus infection 💬
1件: CD19 💬 Obexelimab 💬 Obexelimab 4件: 13, 49, 61, 300 💬
22 Epstein-Barr virus infection 💬
1件: CD19 💬 Tafasitamab 💬 Tafasitamab 1件: 51 💬
23 Epstein-Barr virus infection 💬
4件: CD19, CD3D, CD3E, CD3G 💬 Blinatumomab 💬 Blinatumomab 3件: 11, 46, 49 💬
24 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 Muromonab-CD3 💬 Muromonab 3件: 60, 96, 97 💬
25 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 Otelixizumab 💬 Otelixizumab 1件: 46 💬
26 Epstein-Barr virus infection 💬
3件: CD3D, CD3E, CD3G 💬 Visilizumab 💬 Visilizumab 2件: 96, 97 💬
27 Epstein-Barr virus infection 💬
4件: CD3D, CD3E, CD3G, ITGAL 💬 Anti-human thymocyte immunoglobulin, rabbit 💬 Antithymocyte immunoglobulin (rabbit) 13件: 13, 36, 49, 51, 60, 62, 65, 96, 283, 284, 285, 286, 326 💬
28 Epstein-Barr virus infection 💬
1件: CD3E 💬 Elranatamab 💬 Elranatamab 1件: 28 💬
29 Epstein-Barr virus infection 💬
1件: CD3E 💬 Imvotamab 💬 Imvotamab 2件: 46, 49 💬
30 Epstein-Barr virus infection 💬
1件: CD3E 💬 Mosunetuzumab 💬 Mosunetuzumab 1件: 49 💬
31 Epstein-Barr virus infection 💬
1件: CD3E 💬 Talquetamab 💬 Talquetamab 1件: 28 💬
32 Epstein-Barr virus infection 💬
1件: CD3E 💬 Teclistamab 💬 Teclistamab 1件: 28 💬
33 Epstein-Barr virus infection 💬
1件: CD58 💬 Alefacept 💬 Alefacept 6件: 37, 60, 65, 164, 284, 285 💬
34 Epstein-Barr virus infection 💬
2件: CDK4, CDK6 💬 Abemaciclib 💬 Abemaciclib 1件: 34 💬
35 Epstein-Barr virus infection 💬
2件: HDAC1_2, HDAC1_2 💬 Fimepinostat 💬 Fimepinostat 1件: 75 💬
36 Epstein-Barr virus infection 💬
2件: HDAC1_2, HDAC1_2 💬 Givinostat 💬 Givinostat 2件: 107, 113 💬
37 Epstein-Barr virus infection 💬
2件: HDAC1_2, HDAC1_2 💬 Vorinostat 💬 Vorinostat 2件: 75, 96 💬
38 Epstein-Barr virus infection 💬
1件: ICAM1 💬 Alicaforsen sodium 💬 Alicaforsen 2件: 96, 97 💬
39 Epstein-Barr virus infection 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Sifalimumab 💬 Sifalimumab 1件: 49 💬
40 Epstein-Barr virus infection 💬
13件: IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA, IFNA 💬 Rontalizumab 💬 Rontalizumab 1件: 49 💬
41 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Anifrolumab 💬 Anifrolumab 5件: 46, 49, 50, 51, 53 💬
42 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta 💬 Human interferon beta 5件: 13, 20, 50, 96, 97 💬
43 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa 💬 Interferon alfa 2件: 25, 56 💬
44 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2a 💬 Interferon alfa-2a 1件: 56 💬
45 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon alfa-2b 💬 Interferon alfa-2b 1件: 25 💬
46 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1a 💬 Interferon beta-1a 3件: 13, 96, 97 💬
47 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Interferon beta-1b 💬 Interferon beta-1b 1件: 13 💬
48 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon alfa-2a 💬 Peginterferon alfa-2a 1件: 222 💬
49 Epstein-Barr virus infection 💬
2件: IFNAR1, IFNAR2 💬 Peginterferon beta-1a 💬 Peginterferon beta-1a 1件: 13 💬
50 Epstein-Barr virus infection 💬
1件: IFNB 💬 Dazukibart 💬 Dazukibart 1件: 50 💬
51 Epstein-Barr virus infection 💬
1件: IL6 💬 Olokizumab 💬 Olokizumab 2件: 46, 96 💬
52 Epstein-Barr virus infection 💬
1件: IL6 💬 Siltuximab 💬 Siltuximab 2件: 28, 331 💬
53 Epstein-Barr virus infection 💬
1件: IL6 💬 Sirukumab 💬 Sirukumab 2件: 41, 46 💬
54 Epstein-Barr virus infection 💬
2件: IL6, TNF 💬 Pirfenidone 💬 Pirfenidone 11件: 13, 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 💬
55 Epstein-Barr virus infection 💬
2件: IL6, TNF 💬 Pomalidomide 💬 Pomalidomide 6件: 28, 34, 51, 85, 227, 331 💬
56 Epstein-Barr virus infection 💬
1件: ITGAL 💬 Efalizumab 💬 Efalizumab 9件: 11, 13, 37, 46, 53, 61, 95, 96, 221 💬
57 Epstein-Barr virus infection 💬
1件: JAK1 💬 Abrocitinib 💬 Abrocitinib 2件: 39, 84 💬
58 Epstein-Barr virus infection 💬
1件: JAK1 💬 Baricitinib 💬 Baricitinib 21件:  2 , 13, 40, 41, 46, 49, 50, 51, 53, 54, 84, 93, 107, 135, 162, 265, 268, 269, 300, 325, 345 💬
59 Epstein-Barr virus infection 💬
1件: JAK1 💬 Filgotinib 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
60 Epstein-Barr virus infection 💬
1件: JAK1 💬 Itacitinib 💬 Itacitinib 4件: 46, 51, 97, 228 💬
61 Epstein-Barr virus infection 💬
1件: JAK1 💬 Itacitinib adipate 💬 Itacitinib 4件: 46, 51, 97, 228 💬
62 Epstein-Barr virus infection 💬
1件: JAK1 💬 Ruxolitinib 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
63 Epstein-Barr virus infection 💬
1件: JAK1 💬 Ruxolitinib phosphate 💬 Ruxolitinib 6件: 13, 15, 50, 60, 65, 228 💬
64 Epstein-Barr virus infection 💬
1件: JAK1 💬 Upadacitinib 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
65 Epstein-Barr virus infection 💬
1件: JAK1 💬 Upadacitinib tartrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
66 Epstein-Barr virus infection 💬
1件: JAK1 💬 Upadacitinib hydrate 💬 Upadacitinib 10件: 40, 41, 46, 49, 53, 55, 96, 97, 107, 271 💬
67 Epstein-Barr virus infection 💬
2件: JAK1, JAK3 💬 Peficitinib 💬 Peficitinib 1件: 46 💬
68 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, SYK 💬 Gusacitinib 💬 Gusacitinib 1件: 49 💬
69 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, TYK2 💬 Delgocitinib 💬 Delgocitinib 1件: 50 💬
70 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, TYK2 💬 Filgotinib maleate 💬 Filgotinib 10件: 46, 53, 56, 96, 97, 107, 222, 271, 300, 331 💬
71 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, TYK2 💬 Tofacitinib citrate 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
72 Epstein-Barr virus infection 💬
3件: JAK1, JAK3, TYK2 💬 Tofacitinib 💬 Tofacitinib 22件:  2 , 11, 35, 38, 39, 40, 44, 46, 49, 50, 51, 53, 65, 66, 84, 96, 97, 107, 110, 162, 271, 300 💬
73 Epstein-Barr virus infection 💬
1件: JAK3 💬 Ritlecitinib tosylate 💬 Ritlecitinib 3件: 46, 96, 97 💬
74 Epstein-Barr virus infection 💬
20件: MHC1, MHC1, MHC1, MHC1, MHC1, MHC1, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2, MHC2 💬 Glatiramer acetate 💬 Glatiramer 3件: 13, 96, 156 💬
75 Epstein-Barr virus infection 💬
1件: NFKB1 💬 Iguratimod 💬 Iguratimod 6件: 46, 49, 51, 53, 271, 300 💬
76 Epstein-Barr virus infection 💬
4件: P38, P38, P38, P38 💬 Losmapimod 💬 Losmapimod 2件: 113, 222 💬
77 Epstein-Barr virus infection 💬
4件: P38, P38, P38, P38 💬 Neflamapimod 💬 Neflamapimod 1件:  8  💬
78 Epstein-Barr virus infection 💬
1件: PIK3CA_B_D 💬 Alpelisib 💬 Alpelisib 4件: 138, 278, 279, 280 💬
79 Epstein-Barr virus infection 💬
1件: PIK3CA_B_D 💬 Leniolisib phosphate 💬 Leniolisib 2件: 53, 65 💬
80 Epstein-Barr virus infection 💬
1件: PIK3CA_B_D 💬 Parsaclisib 💬 Parsaclisib 3件: 35, 53, 61 💬
81 Epstein-Barr virus infection 💬
2件: PIK3CA_B_D, PIK3CA_B_D 💬 Copanlisib 💬 Copanlisib 1件: 121 💬
82 Epstein-Barr virus infection 💬
3件: PIK3CA_B_D, PIK3CA_B_D, PIK3CA_B_D 💬 Leniolisib 💬 Leniolisib 2件: 53, 65 💬
83 Epstein-Barr virus infection 💬
1件: RELA 💬 Edasalonexent 💬 Edasalonexent 1件: 113 💬
84 Epstein-Barr virus infection 💬
1件: RIPK1 💬 Eclitasertib 💬 SAR443122 1件: 97 💬
85 Epstein-Barr virus infection 💬
1件: SYK 💬 Fostamatinib 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
86 Epstein-Barr virus infection 💬
1件: SYK 💬 Fostamatinib disodium 💬 Fostamatinib 5件: 46, 49, 61, 63, 66 💬
87 Epstein-Barr virus infection 💬
1件: TNF 💬 Adalimumab 💬 Adalimumab 21件: 19, 37, 38, 40, 41, 46, 55, 56, 84, 96, 97, 107, 151, 160, 162, 164, 222, 226, 269, 270, 271 💬
88 Epstein-Barr virus infection 💬
1件: TNF 💬 Certolizumab pegol 💬 Certolizumab pegol 7件: 37, 46, 49, 96, 107, 226, 271 💬
89 Epstein-Barr virus infection 💬
1件: TNF 💬 Etanercept 💬 Etanercept 16件: 15, 35, 38, 39, 46, 50, 53, 56, 60, 85, 107, 228, 270, 271, 285, 298 💬
90 Epstein-Barr virus infection 💬
1件: TNF 💬 Golimumab 💬 Golimumab 8件: 46, 56, 84, 96, 97, 107, 270, 271 💬
91 Epstein-Barr virus infection 💬
1件: TNF 💬 Infliximab 💬 Infliximab 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 95, 96, 97, 98, 107, 164, 269, 270, 271 💬
92 Epstein-Barr virus infection 💬
1件: TNF 💬 Lenalidomide 💬 Lenalidomide 8件: 16, 26, 28, 34, 49, 284, 300, 331 💬
93 Epstein-Barr virus infection 💬
1件: TNF 💬 Ozoralizumab 💬 Ozoralizumab 1件: 46 💬
94 Epstein-Barr virus infection 💬
1件: TNF 💬 Pegsunercept 💬 Pegsunercept 1件: 46 💬
95 Epstein-Barr virus infection 💬
1件: TNF 💬 Thalidomide 💬 Thalidomide 21件:  2 , 16, 20, 28, 49, 51, 53, 56, 65, 84, 85, 94, 96, 97, 117, 227, 271, 280, 298, 300, 331 💬
96 Epstein-Barr virus infection 💬
1件: TNFRSF5 💬 Bleselumab 💬 Bleselumab 1件: 222 💬
97 Epstein-Barr virus infection 💬
1件: TNFRSF5 💬 Iscalimab 💬 Iscalimab 2件: 49, 53 💬
98 Epstein-Barr virus infection 💬
1件: TNFRSF5 💬 Ravagalimab 💬 Ravagalimab 3件: 46, 53, 97 💬
99 Epstein-Barr virus infection 💬
1件: TYK2 💬 Deucravacitinib 💬 Deucravacitinib 9件: 36, 37, 49, 53, 84, 96, 97, 160, 269 💬
100 Epstein-Barr virus infection 💬
1件: TYK2 💬 Zasocitinib 💬 Zasocitinib 2件: 96, 97 💬