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KEGG DRUG

Search results

No.

Drug (Description in trials)

DrugBank

KEGG DRUG

KEGG GENES

KEGG PATHWAY

Disease ID

Acetate

[1] Acetate

[52] 1, 2, 6, 10, 11, 13, 22, 35, 40, 46, 49, 51, 60, 63, 64, 65, 66, 67, 70, 71, 73, 75, 76, 77, 78, 79, 81, 83, 85, 86, 88, 89, 90, 96, 97, 113, 145, 156, 158, 162, 171, 206, 222, 223, 224, 225, 227, 235, 251, 265, 298, 299 💬

Disease ID	Name
1	Spinal and bulbar muscular atrophy
2	Amyotrophic lateral sclerosis
6	Parkinson disease
10	Charcot-Marie-Tooth disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
22	Moyamoya disease
35	Pemphigus
40	Takayasu arteritis
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
60	Aplastic anemia
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
70	Spinal stenosis
71	Idiopathic osteonecrosis of the femoral head
73	TSH-secreting pituitary adenoma
75	Cushing disease
76	Pituitary gonadotropin secretion hyperthyroidism
77	Growth hormone secreting pituitary adenoma
78	Hypopituitarism
79	Homozygous familial hypercholesterolemia
81	Congenital adrenal hyperplasia
83	Addison disease
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
88	Chronic thromboembolic pulmonary hypertension
89	Lymphangioleiomyomatosis
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
113	Muscular dystrophy
145	West syndrome
156	Rett syndrome
158	Tuberous sclerosis
162	Pemphigoid
171	Wilson disease
206	Fragile X syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
224	Purpura nephritis
225	Congenital nephrogenic diabetes insipidus
227	Osler disease
235	Hypoparathyroidism
251	Urea cycle disorder
265	Lipodystrophy
298	Hereditary pancreatitis
299	Cystic fibrosis

Acetazolamide

[1] Acetazolamide

[2] Acetazolamide ,
Acetazolamide sodium 💬

[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬

Name	Full Name
CA1	carbonic anhydrase 1 isoform a
CA12	carbonic anhydrase 12 isoform 1 precursor
CA13	carbonic anhydrase 13
CA14	carbonic anhydrase 14 precursor
CA2	carbonic anhydrase 2 isoform 1
CA3	carbonic anhydrase 3
CA4	carbonic anhydrase 4 preproprotein
CA5A	carbonic anhydrase 5A, mitochondrial isoform 1 precursor
CA5B	carbonic anhydrase 5B, mitochondrial precursor
CA6	carbonic anhydrase 6 isoform 1 precursor
CA7	carbonic anhydrase 7 isoform 1
CA8	carbonic anhydrase-related protein isoform a
CA9	carbonic anhydrase 9 precursor

[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬

[8] 13, 67, 90, 115, 155, 222, 225, 230 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
67	Polycystic kidney disease
90	Retinitis pigmentosa
115	Hereditary periodic paralysis
155	Acquired aphasia with convulsive disorder
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
230	Alveolar hypoventilation syndrome

Acetazolamide Sandoz 250

[1] Acetazolamide

[2] Acetazolamide ,
Acetazolamide sodium 💬

[13] CA1,
CA12,
CA13,
CA14,
CA2,
CA3,
CA4,
CA5A,
CA5B,
CA6,
CA7,
CA8,
CA9 💬

Name	Full Name
CA1	carbonic anhydrase 1 isoform a
CA12	carbonic anhydrase 12 isoform 1 precursor
CA13	carbonic anhydrase 13
CA14	carbonic anhydrase 14 precursor
CA2	carbonic anhydrase 2 isoform 1
CA3	carbonic anhydrase 3
CA4	carbonic anhydrase 4 preproprotein
CA5A	carbonic anhydrase 5A, mitochondrial isoform 1 precursor
CA5B	carbonic anhydrase 5B, mitochondrial precursor
CA6	carbonic anhydrase 6 isoform 1 precursor
CA7	carbonic anhydrase 7 isoform 1
CA8	carbonic anhydrase-related protein isoform a
CA9	carbonic anhydrase 9 precursor

[6] Bile secretion, Collecting duct acid secretion, Gastric acid secretion, Nitrogen metabolism, Pancreatic secretion, Proximal tubule bicarbonate reclamation 💬

[1] 225 💬

Adempas

[5] 51, 86, 88, 225, 299 💬

Amiloride

[1] Amiloride

[2] Amiloride hydrochloride ,
Amiloride 💬

[3] SCNN1A,
SCNN1B,
SCNN1G 💬

[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬

[5] 13, 67, 222, 225, 299 💬

Anhydrous Amiloride Hydrochloride

[1] Amiloride

[2] Amiloride hydrochloride ,
Amiloride 💬

[3] SCNN1A,
SCNN1B,
SCNN1G 💬

[2] Aldosterone-regulated sodium reabsorption, Taste transduction 💬

[1] 225 💬

Arginine

[1] Arginine

[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬

[16] 2, 21, 46, 57, 58, 67, 72, 96, 97, 98, 113, 210, 223, 225, 251, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
72	Pituitary ADH secretion disorder
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
113	Muscular dystrophy
210	Single Ventricle
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus
251	Urea cycle disorder
299	Cystic fibrosis

Atorvastatin

[1] Atorvastatin

[2] Atorvastatin calcium ,
Atorvastatin 💬

[1] HMGCR 💬

[3] AMPK signaling pathway, Bile secretion, Terpenoid backbone biosynthesis 💬

[21] 13, 22, 46, 49, 51, 58, 63, 67, 79, 84, 88, 93, 96, 97, 160, 222, 225, 265, 271, 297, 299 💬

Disease ID	Name
13	Multiple sclerosis/Neuromyelitis optica
22	Moyamoya disease
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
58	Hypertrophic cardiomyopathy
63	Idiopathic thrombocytopenic purpura
67	Polycystic kidney disease
79	Homozygous familial hypercholesterolemia
84	Sarcoidosis
88	Chronic thromboembolic pulmonary hypertension
93	Primary biliary cholangitis
96	Crohn disease
97	Ulcerative colitis
160	Congenital ichthyosis
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
265	Lipodystrophy
271	Ankylosing spondylitis
297	Alagille syndrome
299	Cystic fibrosis

Behavioral: Water reduction at home

[1] Water

[1] Water 💬

[2] 72, 225 💬

Calcitonin

[1] 225 💬

CALCITONIN (SALMON)

[1] 225 💬

Chlorothiazide

[1] Chlorothiazide

[2] Chlorothiazide ,
Chlorothiazide sodium 💬

[1] SLC12A3 💬

[1] Parathyroid hormone synthesis, secretion and action 💬

[1] 225 💬

Confortid

[1] 225 💬

Desmopressin

[1] Desmopressin

[2] Desmopressin ,
Desmopressin acetate 💬

[2] AVPR2,
F8 💬

[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬

[8] 6, 22, 64, 72, 75, 223, 225, 288 💬

Disease ID	Name
6	Parkinson disease
22	Moyamoya disease
64	Thrombotic thrombocytopenic purpura
72	Pituitary ADH secretion disorder
75	Cushing disease
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus
288	Autoimmune acquired coagulation factor deficiency

DESMOPRESSIN ACETATE TRIHYDRATE

[2] Acetate,
Desmopressin

[2] Desmopressin ,
Desmopressin acetate 💬

[2] AVPR2,
F8 💬

[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬

[1] 225 💬

Desmopressine nasal spray 10 mg/ml, flacon 60 doses

[1] Desmopressin

[2] Desmopressin ,
Desmopressin acetate 💬

[2] AVPR2,
F8 💬

[5] Complement and coagulation cascades, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬

[1] 225 💬

Diagnostic Test: Deamino Arginine Vasopressin (dDAVP)

[2] Arginine,
Vasopressin

[4] Vasopressin ,
Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬

[3] AVPR1A,
AVPR1B,
AVPR2 💬

[6] Calcium signaling pathway, Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption 💬

[1] 225 💬

Esidrix

[1] 225 💬

Fluconazole

[1] Fluconazole

[1] Fluconazole 💬

[3] 67, 96, 225 💬

Hydrochloorthiazide

[1] 225 💬

HYDROCHLOROTHIAZIDE

[1] Hydrochlorothiazide

[1] Hydrochlorothiazide 💬

[1] SLC12A3 💬

[1] Parathyroid hormone synthesis, secretion and action 💬

[5] 13, 67, 222, 225, 235 💬

Hydrochlorothiazide/amiloride

[2] Amiloride,
Hydrochlorothiazide

[3] Hydrochlorothiazide ,
Amiloride hydrochloride ,
Amiloride 💬

[4] SCNN1A,
SCNN1B,
SCNN1G,
SLC12A3 💬

Name	Full Name
SCNN1A	epithelial sodium channel subunit alpha isoform 1
SCNN1B	epithelial sodium channel subunit beta isoform 1
SCNN1G	epithelial sodium channel subunit gamma
SLC12A3	solute carrier family 12 member 3 isoform 3

[3] Aldosterone-regulated sodium reabsorption, Parathyroid hormone synthesis, secretion and action, Taste transduction 💬

[1] 225 💬

INDOMETACIN

[1] 225 💬

Indomethacin

[1] Indomethacin

[2] Indomethacin ,
Indomethacin sodium 💬

[2] PTGS1,
PTGS2 💬

[23] Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis - DNA adducts, Efferocytosis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway 💬

[3] 225, 271, 298 💬

IRM

[2] 72, 225 💬

Losec

[3] 46, 225, 294 💬

Magnesium

[1] Magnesium

[23] 3, 6, 11, 13, 15, 46, 64, 70, 71, 93, 97, 113, 166, 225, 234, 235, 256, 284, 291, 296, 297, 298, 340 💬

Disease ID	Name
3	Spinal muscular atrophy
6	Parkinson disease
11	Myasthenia gravis
13	Multiple sclerosis/Neuromyelitis optica
15	Inclusion body myositis
46	Malignant rheumatoid arthritis
64	Thrombotic thrombocytopenic purpura
70	Spinal stenosis
71	Idiopathic osteonecrosis of the femoral head
93	Primary biliary cholangitis
97	Ulcerative colitis
113	Muscular dystrophy
166	Pseudoxanthoma elasticum
225	Congenital nephrogenic diabetes insipidus
234	Peroxisomal disease (except Adrenoleukodystrophy)
235	Hypoparathyroidism
256	Muscle glycogenosis
284	Diamond-Blackfan anemia
291	Hirschsprung disease, entire colon type
296	Biliary atresia
297	Alagille syndrome
298	Hereditary pancreatitis
340	Primary ciliary dyskinesia

Measure of arginine-stimulated copeptin

[1] Arginine

[3] Arginine hydrochloride ,
Arginine ,
Arginine hydrochloride 💬

[2] 72, 225 💬

Measure of Basal Copeptin level

[2] 72, 225 💬

Metformin

[1] Metformin

[2] Metformin hydrochloride ,
Metformin 💬

Name	Other Names
Metformin hydrochloride	Glucophage GLUMETZA RIOMET METFORMIN METFORMIN ER 500 MG METFORMIN HCL METFORMIN HYDROCHLORIDE EXTENDED RELEASE METFORMIN HYDROCHLORIDE EXTENDED-RELEASE 500MG METFORMIN HYDROCHLORIDE ORAL SOLUTION
Metformin	Metformin

[2] PRKAA1,
PRKAA2 💬

[20] AMPK signaling pathway, Adipocytokine signaling pathway, Alcoholic liver disease, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway 💬

[31] 2, 6, 8, 13, 46, 49, 60, 65, 66, 67, 74, 75, 77, 81, 84, 85, 86, 97, 113, 127, 158, 206, 218, 222, 225, 233, 265, 285, 298, 299, 301 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
60	Aplastic anemia
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
74	Prolactin secreting pituitary adenoma
75	Cushing disease
77	Growth hormone secreting pituitary adenoma
81	Congenital adrenal hyperplasia
84	Sarcoidosis
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
97	Ulcerative colitis
113	Muscular dystrophy
127	Frontotemporal lobar degeneration
158	Tuberous sclerosis
206	Fragile X syndrome
218	Alport syndrome
222	Primary nephrotic syndrome
225	Congenital nephrogenic diabetes insipidus
233	Wolfram syndrome
265	Lipodystrophy
285	Fanconi anemia
298	Hereditary pancreatitis
299	Cystic fibrosis
301	Macular dystrophy

[1] 225 💬

[1] 225 💬

[1] 225 💬

[1] NDI-5001

[1] 225 💬

Omeprazole

[1] Omeprazole

[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬

[2] ATP4A,
ATP4B 💬

[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬

[18] 6, 8, 13, 21, 46, 51, 67, 85, 90, 96, 97, 98, 225, 271, 282, 294, 298, 299 💬

Disease ID	Name
6	Parkinson disease
8	Huntington disease
13	Multiple sclerosis/Neuromyelitis optica
21	Mitochondrial disease
46	Malignant rheumatoid arthritis
51	Scleroderma
67	Polycystic kidney disease
85	Idiopathic interstitial pneumonia
90	Retinitis pigmentosa
96	Crohn disease
97	Ulcerative colitis
98	Eosinophilic gastro-intestinal disorder
225	Congenital nephrogenic diabetes insipidus
271	Ankylosing spondylitis
282	Congenital dyserythropoietic anemia
294	Congenital diaphragmatic hernia
298	Hereditary pancreatitis
299	Cystic fibrosis

OMEPRAZOLE MAGNESIUM

[2] Magnesium,
Omeprazole

[3] Omeprazole ,
Omeprazole sodium ,
Omeprazole magnesium 💬

[2] ATP4A,
ATP4B 💬

[3] Collecting duct acid secretion, Gastric acid secretion, Oxidative phosphorylation 💬

[1] 225 💬

[2] 67, 225 💬

RIOCIGUAT

[1] Riociguat

[1] Riociguat 💬

[3] GUCY1A1,
GUCY1A2,
GUCY1B1 💬

[10] Circadian entrainment, Gap junction, Long-term depression, Oxytocin signaling pathway, Platelet activation, Purine metabolism, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cGMP-PKG signaling pathway 💬

[6] 51, 84, 86, 88, 225, 299 💬

Sevoflurane

[1] Sevoflurane

[1] Sevoflurane 💬

[8] 6, 21, 22, 34, 70, 98, 225, 296 💬

Disease ID	Name
6	Parkinson disease
21	Mitochondrial disease
22	Moyamoya disease
34	Neurofibromatosis
70	Spinal stenosis
98	Eosinophilic gastro-intestinal disorder
225	Congenital nephrogenic diabetes insipidus
296	Biliary atresia

Sildenafil

[1] Sildenafil

[2] Sildenafil citrate ,
Sildenafil 💬

[1] PDE5A 💬

[2] Purine metabolism, cGMP-PKG signaling pathway 💬

[17] 6, 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬

Disease ID	Name
6	Parkinson disease
46	Malignant rheumatoid arthritis
50	Dermatomyositis
51	Scleroderma
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
90	Retinitis pigmentosa
113	Muscular dystrophy
210	Single Ventricle
211	Hypoplastic left heart syndrome
212	Tricuspid atresia
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
278	Huge lymphatic malformation with cervicofacial lesion
294	Congenital diaphragmatic hernia
299	Cystic fibrosis
301	Macular dystrophy

Sildenafil citrate

[1] Sildenafil

[2] Sildenafil citrate ,
Sildenafil 💬

[1] PDE5A 💬

[2] Purine metabolism, cGMP-PKG signaling pathway 💬

[4] 51, 85, 86, 225 💬

Spirix

[1] 225 💬

Spironolactone

[1] Spironolactone

[1] Spironolactone 💬

[1] NR3C2 💬

[1] Aldosterone-regulated sodium reabsorption 💬

[12] 46, 57, 58, 67, 86, 113, 210, 214, 218, 222, 223, 225 💬

Disease ID	Name
46	Malignant rheumatoid arthritis
57	Idiopathic dilated cardiomyopathy
58	Hypertrophic cardiomyopathy
67	Polycystic kidney disease
86	Pulmonary arterial hypertension
113	Muscular dystrophy
210	Single Ventricle
214	Pulmonary atresia with ventricular septum defect
218	Alport syndrome
222	Primary nephrotic syndrome
223	Primary membranoproliferative glomerulonephritis
225	Congenital nephrogenic diabetes insipidus

SUB21605

[1] 225 💬

TOLVAPTAN

[1] Tolvaptan

[1] Tolvaptan 💬

[1] AVPR2 💬

[4] Hormone signaling, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vasopressin-regulated water reabsorption 💬

[5] 67, 72, 86, 222, 225 💬

Vasopressin

[1] Vasopressin

[1] Vasopressin 💬

[3] AVPR1A,
AVPR1B,
AVPR2 💬

[2] 210, 225 💬

VIAGRA

[3] 86, 96, 225 💬

Water

[1] Water

[1] Water 💬

[36] 2, 3, 5, 6, 13, 17, 19, 22, 35, 46, 49, 51, 53, 56, 57, 62, 63, 64, 65, 66, 67, 70, 72, 85, 86, 96, 97, 206, 215, 225, 226, 230, 240, 274, 278, 299 💬

Disease ID	Name
2	Amyotrophic lateral sclerosis
3	Spinal muscular atrophy
5	Progressive supranuclear palsy
6	Parkinson disease
13	Multiple sclerosis/Neuromyelitis optica
17	Multiple system atrophy
19	Lysosomal storage disease
22	Moyamoya disease
35	Pemphigus
46	Malignant rheumatoid arthritis
49	Systemic lupus erythematosus
51	Scleroderma
53	Sjogren syndrome
56	Behcet disease
57	Idiopathic dilated cardiomyopathy
62	Paroxysmal nocturnal hemoglobinuria
63	Idiopathic thrombocytopenic purpura
64	Thrombotic thrombocytopenic purpura
65	Primary immunodeficiency
66	IgA nephropathy
67	Polycystic kidney disease
70	Spinal stenosis
72	Pituitary ADH secretion disorder
85	Idiopathic interstitial pneumonia
86	Pulmonary arterial hypertension
96	Crohn disease
97	Ulcerative colitis
206	Fragile X syndrome
215	Tetralogy of Fallot
225	Congenital nephrogenic diabetes insipidus
226	Interstitial cystitis with Hunners ulcer
230	Alveolar hypoventilation syndrome
240	Phenylketonuria
274	Osteogenesis Imperfecta
278	Huge lymphatic malformation with cervicofacial lesion
299	Cystic fibrosis